Effect of olive, almond and walnut oil on cardiovascular risk factors in type 2 diabetic patients
Tóm tắt
Several studies have demonstrated the benefits of vegetable oil on cardiovascular risk factors in diabetes. The goal of the present study was to compare the effects of olive, almond and walnut oil on serum glucose, lipids and blood pressure in type 2 diabetic patients. In this cross over clinical study 24 hypercholesterolemic type 2 diabetic patients were recruited. Subjects consecutively assigned to consume 40 cc olive, almond and walnut oil daily over a 4-week period with a two-week washout period, accompanied by the Step I diet. Anthropometric measurements, HbA1c, lipid profile and serum glucose and blood pressure were measured initially and at the end of the study. Serum levels of total cholesterol (TC) and LDL-cholesterol at baseline and at the end of trial differed significantly after olive oil (P = 0.007, P = 0.02) and triglyceride (TG) after almond oil (P = 0.02). When the differences of these laboratory levels between olive, almond and walnut were tested, no significant differences were found. Our findings showed olive oil could reduce significantly serum levels of TC and LDL. Almond consumption could decrease TG significantly. Our research could not show significant reduction in blood pressure.
Tài liệu tham khảo
Alerts TC. Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III). JAMA: J Am Med Assoc. 2001;285:2486–97.
Jiang R, Manson JAE, Stampfer MJ, Liu S, Willett WC, Hu FB. Nut and peanut butter consumption and risk of type 2 diabetes in women. JAMA. 2002;288:2554–60.
Storlien LH, Baur LA, Kriketos AD, Pan DA, Cooney GJ, Jenkins AB, et al. Dietary fats and insulin action. Diabetologia. 1996;39:621–31.
Storlien LH, Tapsell LC, Calvert GD. Role of dietary factors: macronutrients. Nutr Rev. 2000;58:S7–9.
Meyer KA, Kushi LH, Jacobs Jr DR, Folsom AR. Dietary fat and incidence of type 2 diabetes in older Iowa women. Diabetes Care. 2001;24:1528–35.
Salmeron J, Hu FB, Manson JE, Stampfer MJ, Colditz GA, Rimm EB, et al. Dietary fat intake and risk of type 2 diabetes in women. Am J Clin Nutr. 2001;73:1019–26.
Spiller GA, Miller A, Olivera K, Reynolds J, Miller B, Morse SJ, et al. Effects of plant-based diets high in raw or roasted almonds, or roasted almond butter on serum lipoproteins in humans. J Am Coll Nutr. 2003;22:195–200.
Fulgoni III VL, Abbey M, Davis P, Hyson D, Jenkins D, Lovejoy J, et al. Almonds significantly lower elevated blood cholesterol and LDL-cholesterol but not HDL-cholesterol or triglycerides in human subjects: results of a meta-analysis. Proceedings of The Fourth International Congress on Vegetarian Nutrition. 2002;8–14.
Jenkins DJA, Kendall CWC, Marchie A, Parker TL, Connelly PW, Qian W, et al. Dose response of almonds on coronary heart disease risk factors: blood lipids, oxidized low-density lipoproteins, lipoprotein (a), homocysteine, and pulmonary nitric oxide a randomized, controlled, crossover trial. Circulation. 2002;106:1327–32.
Kritchevsky D, Tepper SA, Czarnecki SK, Klurfeld DM. Atherogenicity of animal and vegetable protein. Influence of the lysine to arginine ratio. Atherosclerosis. 1982;41:429–31.
Stupans I, Kirlich A, Tuck KL, Hayball PJ. Comparison of radical scavenging effect, inhibition of microsomal oxygen free radical generation, and serum lipoprotein oxidation of several natural antioxidants. J Agric Food Chem. 2002;50:2464–9.
Visioli F, Bellomo G, Galli C. Free radical-scavenging properties of olive oil polyphenols. Biochem Biophys Res Commun. 1998;247:60–4.
Larsen LF, Jespersen J, Marckmann P. Are olive oil diets antithrombotic? Diets enriched with olive, rapeseed, or sunflower oil affect postprandial factor VII differently. Am J Clin Nutr. 1999;70:976–82.
Kontogianni MD, Panagiotakos DB, Chrysohoou C, Pitsavos C, Zampelas A, Stefanadis C. The impact of olive oil consumption pattern on the risk of acute coronary syndromes: the CARDIO2000 case–control study. Clin Cardiol. 2007;30:125–9.
Garg A. Treatment of diabetic dyslipidemia. Am J Cardiol. 1998;81:47B–51B.
Vessby B, Uusitupa M, Hermansen K, Riccardi G, Rivellese AA, Tapsell LC, et al. Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: the KANWU study. Diabetologia. 2001;44:312–9.
Basevi V, Di Mario S, Morciano C, Nonino F, Magrini N. American diabetes association. Standards of medical care in diabetes. Diabetes Care. 2011;34 suppl 1:S11–61.
Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18:499–502.
Kendall CWC, Jenkins DJA, Marchie A, Parker T, Connelly PW, Spiller GA. Dose response of almonds on coronary heart disease risk factors: blood lipids, oxidized low-density lipoproteins, lipoprotein(a), homocysteine, and pulmonary nitric oxide: a randomized, controlled, crossover trial. Circulation. 2002;106:1327–32.
Hyson DA, Schneeman BO, Davis PA. Almonds and almond oil have similar effects on plasma lipids and LDL oxidation in healthy men and women. J Nutr. 2002;132:703–7.
Abbey M, Noakes M, Belling GB, Nestel PJ. Partial replacement of saturated fatty acids with almonds or walnuts lowers total plasma cholesterol and low-density-lipoprotein cholesterol. Am J Clin Nutr. 1994;59:995–9.
Spiller GA, Jenkins DAJ, Bosello O, Gates JE, Cragen LN, Bruce B. Nuts and plasma lipids: an almond-based diet lowers LDL-C while preserving HDL-C. J Am Coll Nutr. 1998;17:285–90.
Lovejoy JC, Most MM, Lefevre M, Greenway FL, Rood JC. Effect of diets enriched in almonds on insulin action and serum lipids in adults with normal glucose tolerance or type 2 diabetes. Am J Clin Nutr. 2002;76:1000.
Jenkins DJA, Kendall CWC, Josse AR, Salvatore S, Brighenti F, Augustin LSA, et al. Almonds decrease postprandial glycemia, insulinemia, and oxidative damage in healthy individuals. J Nutr. 2006;136:2987.
Wien MA, Sabaté JM, Iklé DN, Cole SE, Kandeel FR. Almonds vs complex carbohydrates in a weight reduction program. Int J Obes. 2003;27:1365–72.
Bonanome A, Pagnan A, Biffanti S, Opportuno A, Sorgato F, Dorella M, et al. Effect of dietary monounsaturated and polyunsaturated fatty acids on the susceptibility of plasma low density lipoproteins to oxidative modification. Arterioscler Thromb Vasc Biol. 1992;12:529–33.
Mata P, varez-Sala LA, Rubio MJ, Nuno J, De Oya M. Effects of long-term monounsaturated-vs polyunsaturated-enriched diets on lipoproteins in healthy men and women. Am J Clin Nutr. 1992;55:846–50.
Garg A. High-monounsaturated-fat diets for patients with diabetes mellitus: a meta-analysis. Am J Clin Nutr. 1998;67:577S–82.
Tierney AC, Roche HM. The potential role of olive oil-derived MUFA in insulin sensitivity. Mol Nutr Food Res. 2007;51:1235–48.
Psaltopoulou T, Naska A, Orfanos P, Trichopoulos D, Mountokalakis T, Trichopoulou A. Olive oil, the Mediterranean diet, and arterial blood pressure: the Greek European prospective investigation into cancer and nutrition (EPIC) study. Am J Clin Nutr. 2004;80:1012.
Ferrara LA, Raimondi AS, d’Episcopo L, Guida L, lo Russo A, Marotta T. Olive oil and reduced need for antihypertensive medications. Arch Intern Med. 2000;160:837–42.
Sabate J, Fraser GE, Burke K, Knutsen SF, Bennett H, Lindsted KD. Effects of walnuts on serum lipid levels and blood pressure in normal men. N Engl J Med. 1993;328:603.
Tapsell LC, Gillen LJ, Patch CS, Batterham M, Owen A, Bare M, et al. Including walnuts in a low-fat/modified-fat diet improves HDL cholesterol-to-total cholesterol ratios in patients with type 2 diabetes. Diabetes Care. 2004;27:2777.
Oster P, Arab L, Schellenberg B, Heuck CC, Mordasini R, Schlierf G. Blood pressure and adipose tissue linoleic acid. Res Exp Med. 1979;175:287–91.
Salonen JT, Salonen R, Ihanainen M, Parviainen M, Seppanen R, Kantola M, et al. Blood pressure, dietary fats, and antioxidants. Am J Clin Nutr. 1988;48:1226–32.
Sacks FM. Dietary fats and blood pressure: a critical review of the evidence. Nutr Rev. 1989;47:291–300.