Effect of mutations in Candida antarctica B lipase

Anderson, E.M., Larsson, K.M., Kirk, O., 1998. One biocatalyst—many applications: the use of Candida antarctica B-lipase in organic synthesis, Biocatal. Biotransform. 15, in press. Balcão, 1996, Bioreactors with immobilized lipases: state of the art, Enzyme Microb. Technol., 18, 392, 10.1016/0141-0229(95)00125-5 Björkling, 1992, Lipase catalyzed synthesis of peroxycarbonylic acids and lipase mediated oxidations, Tetrahedron, 48, 4857, 10.1016/S0040-4020(01)81232-1 Bosley, 1997, Immobilization of lipases on porous polypropylene: reduction in esterification efficiency at low loading, J. Am. Oil Chem. Soc., 74, 107, 10.1007/s11746-997-0153-6 Christensen, 1988, High level expression of recombinant genes in Aspergillus oryzae, Biotech., 6, 1419, 10.1038/nbt1288-1419 Hoegh, 1995, Two lipases from Candida antarctica: cloning and expression in Aspergillus oryzae, Can. J. Bot., 73, S869, 10.1139/b95-333 Kirk, 1992, Fatty acid specificity in lipase—catalyzed synthesis of glucoside esters, Biocatalysis, 6, 127, 10.3109/10242429209014888 Parker, 1955, Peroxides. II. preparation, characterization and polarographic behavior of long-chain aliphatic peracids, J. Am. Chem. Soc., 77, 4037, 10.1021/ja01620a023 Patkar, 1993, Purification of two lipases from Candida antarctica and their inhibition by various inhibitors, Ind. J. Chem., 32B, 76 Patkar, 1997, Effect of mutations in non-consensus sequence Thr–X–Ser–X–Gly of Candida antarctica lipase B on lipase specificity, specific activity and thermostability, J. Mol. Catal. B: Enzym., 3, 51, 10.1016/S1381-1177(96)00036-7 Theil, 1995, Lipase-supported synthesis of biologically active compounds, Chem. Rev., 95, 2203, 10.1021/cr00038a017 Uppenberg, 1994, The sequence, crystal structure determination and refinement of two crystal forms of lipase B from Candida antarctica, Structure, 2, 293, 10.1016/S0969-2126(00)00031-9 Uppenberg, 1995, Crystallographic and molecular-modeling studies of lipase B from Candida antarctica reveal a stereospecific pocket for secondary alcohols, Biochemistry, 34, 16838, 10.1021/bi00051a035 de Zoete, 1993, Selective oxidation of penicillin G with hydrogen peroxide and with enzymatically generated peroxyoctanoic acid, Recl. Trav. Chim. Pays-Bas, 112, 462, 10.1002/recl.19931120706