Effect of multidrug resistance gene-1 (ABCB1) polymorphisms on the single-dose pharmacokinetics of cloxacillin in healthy adult Chinese men

Paton, 1986, Comparative bioavailability and half-lives of cloxacillin and flucloxacillin, Int J Clin Pharmacol Res, 6, 347 Murai, 1983, Comparative pharmacokinetics of metabolism and urinary excretion of isoxazolylpenicillins in man, Chem Pharm Bull (Tokyo), 31, 3292, 10.1248/cpb.31.3292 Bins, 1988, Saturation of the tubular excretion of beta-lactam antibiotics, Br J Clin Pharmacol, 25, 41, 10.1111/j.1365-2125.1988.tb03280.x Sutherland, 1970, Flucloxacillin, a new isox-azolyl penicillin, compared with oxacillin, cloxacillin, and dicloxacillin, Br Med J, 4, 455, 10.1136/bmj.4.5733.455 Susanto, 2002, Can the enhanced renal clearance of antibiotics in cystic fibrosis patients be explained by P-glycoprotein transport?, Pharm Res, 19, 457, 10.1023/A:1015191511817 Wu, 2005, Predicting drug disposition via application of BCS: Transport/absorption/elimination interplay and development of a biopharmaceutics drug disposition classification system, Pharm Res, 22, 11, 10.1007/s11095-004-9004-4 Marzolini, 2004, Polymorphisms in human MDR1 (P-glycoprotein): Recent advances and clinical relevance, Clin Pharmacol Ther, 75, 13, 10.1016/j.clpt.2003.09.012 Ieiri, 2004, The MDR1 (ABCB1) gene polymorphism and its clinical implications, Clin Pharmacokinet, 43, 553, 10.2165/00003088-200443090-00001 Kim, 2001, Identification of functionally variant MDR1 alleles among European Americans and African Americans, Clin Pharmacol Ther, 70, 189, 10.1067/mcp.2001.117412 Tang, 2002, Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations, Pharmacogenetics, 2, 437, 10.1097/00008571-200208000-00004 Sai, 2003, Haplotype analysis of ABCB1/ MDR1 blocks in a Japanese population reveals genotype-dependent renal clearance of irinotecan, Pharma-cogenetics, 13, 741, 10.1097/00008571-200312000-00005 Salama, 2006, MDR1 haplotypes significantly minimize intracellular uptake and transcellular P-gp substrate transport in recombinant LLC-PK1 cells, J Pharm Sci, 95, 2293, 10.1002/jps.20717 Teare, 1982, High-pressure liquid chromatographic assay of cloxacil-lin in serum and urine, J Pharm Sci, 71, 938, 10.1002/jps.2600710826 Gibaldi, 1982 Ameyaw, 2001, MDR1 pharmacogenetics: Frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity, Pharmacogenetics, 11, 217, 10.1097/00008571-200104000-00005 De Muth, 1999 Park, 2007, Genetic polymorphisms in the ABCB1 gene and the effects of fen-tanyl in Koreans, Clin Pharmacol Ther, 81, 539, 10.1038/sj.clpt.6100046 Sekine, 1997, Expression cloning and characterization of a novel multispecific organic anion transporter, J Biol Chem, 272, 18526, 10.1074/jbc.272.30.18526 Terada, 1997, Recognition of beta-lactam antibiotics by rat peptide transporters PEPT1 and PEPT2, in LLC-PK1 cells, Am J Physiol, 273, F706 Luckner, 2005, Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: Analysis of affinity constants and comparison with PEPT1, Eur J Pharm Biopharm, 59, 17, 10.1016/j.ejpb.2004.07.008 Beringer, 2008, Lack of effect of P-glycoprotein inhibition on renal clearance of dicloxacillin in patients with cystic fibrosis, Pharmacotherapy, 28, 883, 10.1592/phco.28.7.883 Putnam, 2005, Effect of the MDR1 C3435T variant and P-glycoprotein induction on dicloxacillin pharma-cokinetics, J Clin Pharmacol, 45, 411, 10.1177/0091270004273492 Shen, 1999, Single-nucleotide polymorphisms can cause different structural folds of mRNA, Proc Natl Acad Sci U S A, 96, 7871, 10.1073/pnas.96.14.7871 Bosch, 2006, Pharmacoge-netic screening of CYP3A and ABCB1 in relation to population pharmacokinetics of docetaxel, Clin Cancer Res, 12, 5786, 10.1158/1078-0432.CCR-05-2649