Effect of methionine and vitamin C supplementation on pulmonary glutathione-s-transferase and glutathione levels in ageing rats

Springer Science and Business Media LLC - Tập 8 - Trang 33-35 - 1993
Harbans Lal1, Kiran Chugh1, Varinder Saini2, Jasbinder Kaur1, A. S. Saini1
1Department of Biochemistry and Chest, Medical College, Rohtak
2Department of Tuberculosis, Medical College, Rohtak

Tóm tắt

Glutathione-5-transferase (GST) and glutathione (GSH) levels were estimated in the lungs of 3 and 30 months old rats. GST activity was found to be significantly reduced in the old rats (30 months age) compared to the young rats (3 months age). In old rats, with methionine supplementation GST activity was increased whereas with vitamin C supplementation GSH levels were increased. The data show that the supplementation of methionine as well as of vitamin C have beneficial effect on the scavenging system and protect lungs against the free radical damage during ageing.

Tài liệu tham khảo

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