Effect of lentivirus-induced shRNA silencing CXCR4 gene on proliferation and apoptosis in human esophageal carcinoma cell line Eca109

Sasaki K, Natsugoe S, Ishigami S, et al. Expression of CXCL12 and its receptor CXCR4 correlates with lymph node metastasis in submucosal esophageal cancer. J Surg Oncol 2008; 97: 433–438.

Aiuti A, Tavian M, Cipponi A, et al. Expression of CXCR4, the receptor for stromal cell-derived factor-1 on fetal and adult human lympho-hematopoietic progenitors. Eur J Immunol 1999; 29: 1823–1831.

Jinquan T, Quan S, Jacobi HH, et al. CXC chemokine receptor 4 expression and stromal cell-derived factor-1 alpha-induced chemotaxis in CD4+T lymphocytes are regulated by interleukin-4 and interleukin-10. Immunology 2000; 99: 402–410.

Nanki T, Hayashida K, El-Gabalawy HS, et al. Stromal cell-derived factor-1-CXC chemokine receptor 4 interactions play a central role in CD4+T cell accumulation in rheumatoid arthritis synovium. J Immunol 2000; 165: 6590–6598.

Sasaki K, Natsugoe S, Ishigami S, et al. Expression of CXCL12 and its receptor CXCR4 in esophageal squamous cell carcinoma. Oncol Rep 2009; 21: 65–71.

Koishi K, Yoshikawa R, Tsujimura T, et al. Persistent CXCR4 expression after preoperative chemoradiotherapy predicts early recurrence and poor prognosis in esophageal cancer. World J Gastroenterol 2006; 12: 7585–7590.

Juarez J, Bradstock KF, Gottlieb DJ, et al. Effects of inhibitors of the chemokine receptor CXCR4 on acute lymphoblastic leukemia cells in vitro. Leukemia 2003; 17: 1294–1300.

Sehgal A, Keener C, Boynton A L, et al. CXCR4, a chemokine receptor, is overexpressed in and required for proliferation of glioblastoma tumor cells. J Surg Oncol 1998; 69: 99–104.

Wang DF, Lou N, Zeng CG, et al. Expression of CXCL12/CXCR4 and its correlation to prognosis in esophageal squamous cell carcinoma. Aizheng 2009; 28: 187–192 (Chinese).

Xia JR, Liu NF, Zhu NX. Specific siRNA targeting the receptor for advanced glycation end products inhibits experimental hepatic fibrosis in rats. Int J Mol Sci 2008; 9: 638–661.

Lee WC, Berry R, Hohenstein P, et al. siRNA as a tool for investigating organogenesis: The pitfalls and the promises. Organogenesis 2008; 4: 176–181.

Brummelkamp TR, Bernards R, Agami R. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2002; 2: 243–247.

Li M, Rossi JJ. Lentiviral vector delivery of siRNA and shRNA encoding genes into cultured and primary hematopoietic cells. Methods Mol Biol 2005; 309: 261–272.

Fish RJ, Kruithof EK. Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors. BMC Mol Biol 2004; 5: 9.

Nishitsuji H, Ikeda T, Miyoshi H, et al. Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells. Microbes Infect 2004; 6: 76–85.

Scherr M, Battmer K, Dallmann I, et al. Inhibition of GM-CSF receptor function by stable RNA interference in a NOD/SCID mouse hematopoietic stem cell transplantation model. Oligonucleotides 2003; 13: 353–363.

Scherr M, Battmer K, Ganser A, et al. Modulation of gene expression by lentiviral-mediated delivery of small interfering RNA. Cell Cycle 2003; 2: 251–257.

Orimo A, Gupta PB, Sgroi DC, et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005; 121: 335–348.

Kaifi JT, Yekebas EF, Schurr P, et al. Tumor-cell homing to lymph nodes and bone marrow and CXCR4 expression in esophageal cancer. J Natl Cancer Inst 2005; 97: 1840–1847.

Samara GJ, Lawrence DM, Chiarelli CJ, et al. CXCR4-mediated adhesion and MMP-9 secretion in head and neck squamous cell carcinoma. Cancer Lett 2004; 214: 231–241.

Lapteva N, Yang AG, Sanders DE, et al. CXCR4 knockdown by small interfering RNA abrogates breast tumor growth in vivo. Cancer Gene Ther 2005; 12: 84–89.

Porcile C, Bajetto A, Barbieri F, et al. Stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12) stimulates ovarian cancer cell growth through the EGF receptor transactivation. Exp Cell Res 2005; 308: 241–253.

Salmaggi A, Gelati M, Pollo B, et al. CXCL12 in malignant glial tumors: a possible role in angiogenesis and cross-talk between endothelial and tumoral cells. J Neurooncol 2004; 67: 305–317.

Wei L, Kong PY, Chen XH, et al. Effect of anti-CXCR4 monoclonal antibody on adhesion and proliferation of human acute myelocytic leukemia cell line HL-60. Aizheng 2004; 23: 1273–1277 (Chinese).

Lataillade JJ, Clay D, Dupuy C, et al. Chemokine SDF-1 enhances circulating CD34+ cell proliferation in synergy with cytokine possible role in progenitor survival. Blood 2000; 95: 756–768.

Bonni A, Brunet A, West AE, et al. Cell survival promoted by the ras-MAPK signaling pathway by transcription-dependent and independent mechanisms. Science 1999; 286: 1309–1310.