Effect of an Intensive Glucose Management Protocol on the Mortality of Critically Ill Adult Patients

Wahab, 2002, Is blood glucose an independent predictor of mortality in acute myocardial infarction in the thrombolytic era?, J Am Coll Cardiol, 40, 1748, 10.1016/S0735-1097(02)02483-X

Capes, 2000, Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview, Lancet, 355, 773, 10.1016/S0140-6736(99)08415-9

Malmberg, 1999, Circulation, 99, 2626, 10.1161/01.CIR.99.20.2626

Foo, 2003, A single serum glucose measurement predicts adverse outcomes across the whole range of acute coronary syndromes, Heart, 89, 512, 10.1136/heart.89.5.512

Malmberg, 1997, Prospective randomised study of intensive insulin treatment on long term survival after acute myocardial infarction in patients with diabetes mellitus, BMJ, 314, 1512, 10.1136/bmj.314.7093.1512

Sala, 2002, Short-term mortality of myocardial infarction patients with diabetes or hyperglycaemia during admission, J Epidemiol Community Health, 56, 707, 10.1136/jech.56.9.707

Williams, 2002, Effects of admission hyperglycemia on mortality and costs in acute ischemic stroke, Neurology, 59, 67, 10.1212/WNL.59.1.67

Capes, 2001, Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients: a systematic overview, Stroke, 32, 2426, 10.1161/hs1001.096194

Kagansky, 2001, The role of hyperglycemia in acute stroke, Arch Neurol, 58, 1209, 10.1001/archneur.58.8.1209

Parsons, 2002, Acute hyperglycemia adversely affects stroke outcome: a magnetic resonance imaging and spectroscopy study, Ann Neurol, 52, 20, 10.1002/ana.10241

Bruno, 2002, Admission glucose level and clinical outcomes in the NINDS rt-PA Stroke Trial, Neurology, 59, 669, 10.1212/WNL.59.5.669

Estrada, 2003, Outcomes and perioperative hyperglycemia in patients with or without diabetes mellitus undergoing coronary artery bypass grafting, Ann Thorac Surg, 75, 1392, 10.1016/S0003-4975(02)04997-4

Guvener, 2002, Perioperative hyperglycemia is a strong correlate of postoperative infection in type II diabetic patients after coronary artery bypass grafting, Endocr J, 49, 531, 10.1507/endocrj.49.531

Latham, 2001, The association of diabetes and glucose control with surgical-site infections among cardiothoracic surgery patients, Infect Control Hosp Epidemiol, 22, 607, 10.1086/501830

Golden, 1999, Perioperative glycemic control and the risk of infectious complications in a cohort of adults with diabetes, Diabetes Care, 22, 1408, 10.2337/diacare.22.9.1408

Yendamuri, 2003, Admission hyperglycemia as a prognostic indicator in trauma, J Trauma, 55, 33, 10.1097/01.TA.0000074434.39928.72

Krinsley, 2003, Association between hyperglycemia and increased hospital mortality in a heterogeneous population of critically ill patients, Mayo Clin Proc, 78, 1471, 10.4065/78.12.1471

Van den Berghe, 2001, Intensive insulin therapy in critically ill patients, N Engl J Med, 345, 1359, 10.1056/NEJMoa011300

Furnary, 2003, Continuous insulin infusion reduces mortality in patients with diabetes undergoing coronary artery bypass grafting, J Thorac Cardiovasc Surg, 125, 1007, 10.1067/mtc.2003.181

Knaus, 1985, APACHE II: a severity of disease classification system, Crit Care Med, 13, 818, 10.1097/00003246-198510000-00009

Knaus, 1991, The APACHE III prognostic system: risk prediction of hospital mortality for critically ill hospitalized adults, Chest, 100, 1619, 10.1378/chest.100.6.1619

Bone, 1992, Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis, Chest, 101, 1644, 10.1378/chest.101.6.1644

Bernard, 2001, Efficacy and safety of recombinant human activated protein C for severe sepsis, N Engl J Med, 344, 699, 10.1056/NEJM200103083441001

Acute Respiratory Distress Syndrome Network, 2000, Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome, N Engl J Med, 342, 1301, 10.1056/NEJM200005043421801

Coursin, 2003, How sweet is euglycemia in critically ill patients? [editorial], Mayo Clin Proc, 78, 1460, 10.4065/78.12.1460

Das, 2001, Is insulin an antiinflammatory molecule?, Nutrition, 17, 409, 10.1016/S0899-9007(01)00518-4

Das, 2002, Is insulin an endogenous cardioprotector?, Crit Care, 6, 389, 10.1186/cc1535

Hansen, 2003, Intensive insulin therapy exerts antiinflammatory effects in critically ill patients and counteracts the adverse effect of low mannose-binding lectin levels, J Clin Endocrinol Metab, 88, 1082, 10.1210/jc.2002-021478

Van den Berghe, 2003, Outcome benefit of intensive insulin therapy in the critically ill: insulin dose versus glycemic control, Crit Care Med, 31, 359, 10.1097/01.CCM.0000045568.12881.10

Finney, 2003, Glucose control and mortality in critically ill patients, JAMA, 290, 2041, 10.1001/jama.290.15.2041

Annane, 2003, Hormone replacement therapy for the critically ill [editorial], Crit Care Med, 31, 634, 10.1097/01.CCM.0000045569.14948.F2

Van den Berghe, 2004, Optimal control of glycemia among critically ill patients [letter], JAMA, 291, 1198, 10.1001/jama.291.10.1198-b

Finney, 2004, Optimal control of glycemia among critically ill patients [reply], JAMA, 291, 1199, 10.1001/jama.291.10.1199-a