Effect of acetylsalicylate on surgical bleeding, postoperative mortality and allograft survival in rats undergoing heart transplantation
Tóm tắt
18 rats were treated with L-ASA before heart transplantation and daily thereafter until death or rejection. 22 animals acted as controls. A significantly higher post-operative mortality rate, without any significant modification of the transplant survival time, was found in L-ASA-treated group.
Tài liệu tham khảo
K.A. Porter, R.Y. Calne and C.F. Zukoski, Lab. Invest.13, 810 (1964).
A. MacDonald, G.J. Busch, J.L. Alexander, E.A. Pheteplace, J. Menzoian and J.E. Murray, Transplantation9, 1 (1970).
K. Messmer, C. Hammer, W. Land, L. Fiedler, W. Klovekorn, K. Holper, G. Lob, D. Merzel and W. Brendel, Transpl. Proc.3, 542 (1971).
G. Claes, Scand. J. Urol. Nephrol., suppl.10, 1 (1972).
L.M. Aledort, R. Taub, L. Burrows, E. Leiter, S. Glabman, M. Haimov, G. Nirmul and S. Berger, in: Platelets and Thrombosis, p. 263. Ed. S. Sherry and A. Scriabine. Urban & Schwarzenberg, München 1974.
I.H. Shehadeh, R.D. Guttmann, R.R. Lindquist and F. Rodriguez-Erdmann, Transplantation10, 75 (1970).
K.A. Porter, J.B. Dossetor, T.L. Marchioro, W.S. Peart, J.M. Rendall, T.E. Starzl and P.I. Terasaki, Lab. Invest.16, 153 (1967).
P. Kincaid-Smith, Lancet2, 920 (1969).
T.H. Matew, P. Kincaid-Smith, D.H. Clyne, B.M. Saker, R.S. Naura and P.J. Morris, Lancet1, 1307 (1974).
I. Reyers, M.B. Donati and G. de Gaetano, Experientia34, 644 (1978).
D.W. Van Bekkum, G.A. Heystek and R.L. Marquet, Transplantation8, 678 (1969).
S. Villa and G. de Gaetano, Prostaglandins14, 1117 (1977).