Effect of Hydrocortisone on 21-Day Mortality or Respiratory Support Among Critically Ill Patients With COVID-19

JAMA - Journal of the American Medical Association - Tập 324 Số 13 - Trang 1298 - 2020
Pierre‐François Dequin1,2,3, Nicholas Heming4,5, Ferhat Meziani6,7, Gaëtan Plantefève8, Guillaume Voiriot9,10, Julio Badié11, Bruno François12,13,14, Cécile Aubron15,16, Jean-Damien Ricard17, Stéphan Ehrmann1,2,3, Youenn Jouan1,2,3, Antoine Guillon1,2,3, M Leclerc18, Carine Coffre18, Hélène Bourgoin19, Céline Lengellé20, Caroline Caille-Fénérol12,13, Elsa Tavernier1, Sarah Zohar21, Bruno Giraudeau1,22, Djillali Annane4,5, Amélie Le Gouge1
1INSERM CIC1415, CHU de Tours, Tours, France
2INSERM U1100, Centre d'Etude des Pathologies Respiratoires, Université de Tours, Tours, France
3Médecine Intensive-Réanimation, CHU de Tours, Tours, France
4INSERM U1173, Université de Versailles SQY-Université Paris Saclay, Garches, France
5Médecine Intensive Réanimation, Hôpital Raymond Poincaré (GHU APHP Université Paris Saclay), Garches, France, and RHU RECORDS and FHU SEPSIS
6INSERM UMR 1260, Université de Strasbourg, Strasbourg, France
7Médecine Intensive Réanimation, Nouvel Hôpital Civil, Hôpitaux universitaires de Strasbourg, Strasbourg, France
8Réanimation Polyvalente, CH Victor Dupouy, Argenteuil, France
9Médecine Intensive Réanimation, Hôpital Tenon (Assistance Publique–Hôpitaux de Paris), Paris, France
10Sorbonne Université, Paris, France
11Réanimation Polyvalente, Hôpital Nord Franche-Comté, Trevenans, France
12CHU Limoges (Centre Hospitalier Universitaire Dupuytren - 2 avenue Martin Luther King 87042 LIMOGES - France)
13CIC1435 - Centre d'Investigation Clinique de Limoges (Centre Hospitalier Universitaire Dupuytren, 2 avenue Martin Luther King, 87042 Limoges Cedex - France)
14INSERM CIC 1435, CHU de Limoges, Limoges, France
15Médecine Intensive Réanimation, CHRU de Brest, Brest, France
16Université de Bretagne Occidentale, Brest, France
17Université de Paris, IAME U1137, Médecine Intensive Réanimation, DMU ESPRIT, Hôpital Louis Mourier, Assistance Publique–Hôpitaux de Paris, Colombe, France
18Délégation à la Recherche Clinique et à l’Innovation, CHU de Tours, Tours, France
19Pharmacie à Usage Interne, CHU de Tours, Tours, France
20Centre régional de pharmacovigilance et d'information sur le médicament, service de pharmacosurveillance, CHU de Tours, Tours, France
21Inserm, Centre de Recherche des Cordeliers, Sorbonne Université, Université de Paris, Paris, France
22Université de Tours, Université de Nantes, INSERM SPHERE U1246, Tours, France

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Tài liệu tham khảo

Wu, 2020, Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72?314 cases from the Chinese Center for Disease Control and Prevention., JAMA, 323, 1239, 10.1001/jama.2020.2648

Grasselli, 2020, Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region, Italy., JAMA, 323, 1574, 10.1001/jama.2020.5394

Beigel, 2020, Remdesivir for the treatment of Covid-19—preliminary report., N Engl J Med, 10.1056/NEJMoa2007764

Huang, 2020, Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China., Lancet, 395, 497, 10.1016/S0140-6736(20)30183-5

Moore, 2020, Cytokine release syndrome in severe COVID-19., Science, 368, 473, 10.1126/science.abb8925

Sinha, 2020, Is a “cytokine storm” relevant to COVID-19?, JAMA Intern Med, 10.1001/jamainternmed.2020.3313

Guillon, 2020, Pulmonary immune responses against SARS-CoV-2 infection: harmful or not?, Intensive Care Med, 10.1007/s00134-020-06170-8

Jouan, 2020, Functional alteration of innate T cells in critically ill patients with COVID-19., J Exp Med, 10.1084/jem.20200872

Sanders, 2020, Pharmacologic treatments for coronavirus disease (COVID-19): a review., JAMA, 323, 1824

Arabi, 2020, Critical care management of adults with community-acquired severe respiratory viral infection., Intensive Care Med, 46, 315, 10.1007/s00134-020-05943-5

Russell, 2020, Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury., Lancet, 395, 473, 10.1016/S0140-6736(20)30317-2

Moreno, 2018, Corticosteroid treatment in critically ill patients with severe influenza pneumonia: a propensity score matching study., Intensive Care Med, 44, 1470, 10.1007/s00134-018-5332-4

Wu, 2020, Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China., JAMA Intern Med, 180, 1, 10.1001/jamainternmed.2020.0994

RECOVERY Collaborative Group, 2020, Dexamethasone in hospitalized patients with COVID-19: preliminary report., N Engl J Med

Lan, 1983, Discrete sequential boundaries for clinical trials., Biometrika, 70, 659, 10.2307/2336502

Fine, 1997, A prediction rule to identify low-risk patients with community-acquired pneumonia., N Engl J Med, 336, 243, 10.1056/NEJM199701233360402

Vincent, 1996, The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure., Intensive Care Med, 22, 707, 10.1007/BF01709751

Papazian, 2019, Formal guidelines: management of acute respiratory distress syndrome., Ann Intensive Care, 9, 69, 10.1186/s13613-019-0540-9

Torres, 2015, Effect of corticosteroids on treatment failure among hospitalized patients with severe community-acquired pneumonia and high inflammatory response: a randomized clinical trial., JAMA, 313, 677, 10.1001/jama.2015.88

Fine, 1999, A proportional hazards model for the sub-distribution of a competing risk., JASA, 94, 496, 10.1080/01621459.1999.10474144

Sterne, 2020, Corticosteroid therapy for critically ill patients with COVID-19: a structured summary of a study protocol for a prospective meta-analysis of randomized trials., Trials, 21, 734, 10.1186/s13063-020-04641-3

Le Gall, 1993, A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study., JAMA, 270, 2957, 10.1001/jama.1993.03510240069035

Blum, 2015, Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial., Lancet, 385, 1511, 10.1016/S0140-6736(14)62447-8

Siemieniuk, 2015, Corticosteroid therapy for patients hospitalized with community-acquired pneumonia: a systematic review and meta-analysis., Ann Intern Med, 163, 519, 10.7326/M15-0715

Stockman, 2006, SARS: systematic review of treatment effects., PLoS Med, 3, 10.1371/journal.pmed.0030343

Arabi, 2018, Corticosteroid therapy for critically ill patients with Middle East Respiratory Syndrome., Am J Respir Crit Care Med, 197, 757, 10.1164/rccm.201706-1172OC

Lee, 2004, Effects of early corticosteroid treatment on plasma SARS-associated coronavirus RNA concentrations in adult patients., J Clin Virol, 31, 304, 10.1016/j.jcv.2004.07.006

Yang, 2020, The effect of corticosteroid treatment on patients with coronavirus infection: a systematic review and meta-analysis., J Infect, 81, e13, 10.1016/j.jinf.2020.03.062

Dequin, 2020, Embedding a COVID-19 group sequential clinical trial within an ongoing trial: lessons from an unusual experience., Stat Biopharmaceut Res, 10.1080/19466315.2020.1800509

COVID-19 dashboard. Johns Hopkins Center for Systems Science and Engineering. Accessed August 17, 2020. https://coronavirus.jhu.edu/map.html

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JAMA - Journal of the American Medical Association

Tập 324 Số 13

1298

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