Effect of Hydration on Silk Film Material Properties

Macromolecular Bioscience - Tập 10 Số 4 - Trang 393-403 - 2010
Brian D. Lawrence1,2, Scott E. Wharram3, Jonathan A. Kluge2, Gary G. Leisk4, Fiorenzo G. Omenetto2,5, Mark I. Rosenblatt6, David L. Kaplan2
1Department of Biomedical Engineering, Cornell University, 101 Weill Hall, Ithaca, NY 14853, USA
2Department of Biomedical Engineering, Tufts University, Science and Technology Center, 4 Colby St., Medford, MA 02155, USA
3Department of Plastics Engineering, University of Massachusetts at Lowell, 1 University Avenue, Lowell, MA 01854, USA
4Department of Mechanical Engineering, Tufts University, 204 Anderson Hall, 200 College Avenue, Medford, MA 02155, USA
5Department of Ophthalmology, Weill Medical College of Cornell University, 1300 York Avenue, New York City, NY 10065, USA
6Margaret M. Dyson Vision Research Institute, Weill Cornell Medical College, New York, NY 10021, USA

Tóm tắt

AbstractEffects of hydration on silk fibroin film properties were investigated for water‐annealed and MeOH‐treated samples. Hydration increased thickness by 60% for MeOH‐immersed films, while water‐annealed samples remained constant. MeOH‐immersed films showed an 80% mass loss due to water, while water‐annealed lost only 40%. O2 permeability was higher in MeOH‐immersed films with Dk values of 10−10 (mL O2 · cm) · (cm−1 · s−1 · mmHg−1), while those of water‐annealed films reached only one fifth of this value. All films showed a decrease in Young's modulus and increased plastic deformation by two orders of magnitude when submerged in saline solution. FT‐IR showed that β‐sheet content in water‐annealed films increased with increasing water vapor pressure, while MeOH‐immersed films showed no change.magnified image

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Macromolecular Bioscience

Tập 10 Số 4

393-403

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