Economic impact of rapid diagnostic methods in Clinical Microbiology: Price of the test or overall clinical impact

Rafael Cantón1, Elia Gómez G. de la Pedrosa1
1Servicio de Microbiología, Hospital Universitario Ramón y Cajal e Instituto de Investigación Sanitaria (IRYCIS), Red Española de Investigación en Patología Infecciosa (REIPI), Madrid, Spain

Tài liệu tham khảo

Patel, 2016, New developments in clinical bacteriology laboratories, Mayo Clin Proc, 91, 1448, 10.1016/j.mayocp.2016.06.020 Fournier, 2013, Modern clinical microbiology: new challenges and solutions, Nat Rev Microbiol, 11, 574, 10.1038/nrmicro3068 Drancourt, 2016, The point-of-care laboratory in Clinical Microbiology, Clin Microbiol Rev, 29, 429, 10.1128/CMR.00090-15 Estem, 2016, HIV Self-Testing: a review of current implementation and fidelity, Curr HIV/AIDS Rep, 13, 107, 10.1007/s11904-016-0307-y 2016 Buchan, 2014, Emerging technologies for the clinical microbiology laboratory, Clin Microbiol Rev, 27, 783, 10.1128/CMR.00003-14 Morel, 2016 Tenover, 2010, Potential impact of rapid diagnostic tests on improving antimicrobial use, Ann N Y Acad Sci, 1213, 70, 10.1111/j.1749-6632.2010.05827.x Dixon, 2015, A systematic review of matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry compared to routine microbiological methods for the time taken to identify microbial organisms from positive blood cultures, Eur J Clin Microbiol Infect Dis, 34, 863, 10.1007/s10096-015-2322-0 Zhang, 2015, Multiplex polymerase chain reaction tests for detection of pathogens associated with gastroenteritis, Clin Lab Med, 35, 461, 10.1016/j.cll.2015.02.006 Buehler, 2016, Effectiveness of practices to increase timeliness of providing targeted therapy for inpatients with bloodstream infections: a laboratory medicine best practices systematic review and meta-analysis, Clin Microbiol Rev, 29, 59, 10.1128/CMR.00053-14 Diekema, 2013, Rapid detection of antibiotic-resistant organism carriage for infection prevention, Clin Infect Dis, 56, 1614, 10.1093/cid/cit038 Caliendo, 2013, Better tests, better care: improved diagnostics for infectious diseases, Clin Infect Dis, 57, S139, 10.1093/cid/cit578 Seng, 2009, Ongoing revolution in bacteriology: routine identification of bacteria by matrix-assisted laser desorption ionization time-of-flight mass spectrometry, Clin Infect Dis, 49, 543, 10.1086/600885 Gómez, 2016, Estudios de coste efectividad con MALDI TOF e impacto clínico, Enferm Infecc Microbiol Clin, 34, 47, 10.1016/S0213-005X(16)30191-4 Desmet, 2016, Broad-range PCR coupled with electrospray ionization time of flight mass spectrometry for detection of bacteremia and fungemia in patients with neutropenic fever, J Clin Microbiol, 54, 2513, 10.1128/JCM.01066-16 Stevenson, 2016, Sepsis: The LightCycler SeptiFast Test MGRADE® SepsiTest™ and IRIDICA BAC BSI assay for rapidly identifying bloodstream bacteria and fungi: a systematic review and economic evaluation, Health Technol Assess, 20, 1 Bouricha, 2014, Point-of-care syndrome-based, rapid diagnosis of infections on commercial ships, J Travel Med, 21, 12, 10.1111/jtm.12090 Clerc, 2010, Routine use of point-of-care tests: usefulness and application in clinical microbiology, Clin Microbiol Infect, 16, 1054, 10.1111/j.1469-0691.2010.03281.x Moore, 2013, Point-of-care tests for infection control: should rapid testing be in the laboratory or at the front line?, J Hosp Infect, 85, 1, 10.1016/j.jhin.2013.06.005 Brenwald, 2010, Feasibility study of a real-time PCR test for methicillin-resistant Staphylococcus aureus in a point of care setting, J Hosp Infect, 74, 245, 10.1016/j.jhin.2009.09.007 Goldenberg, 2014, Point-of-care testing for Clostridium difficile infection: a real-world feasibility study of a rapid molecular test in two hospital settings, Infect Dis Ther, 3, 295, 10.1007/s40121-014-0038-6 2011 Cohen-Bacrie, 2011, Revolutionizing clinical microbiology laboratory organization in hospitals with in situ point-of-care, PLoS ONE, 6, 22403, 10.1371/journal.pone.0022403 Real Decreto Legislativo 1/2015, de 24 de julio, por el que se aprueba el texto refundido de la Ley de garantías y uso racional de los medicamentos y productos sanitarios. BOE núm. 177, 25 de julio de 2015; p. 62935–3030. Prieto, 2004, Análisis de coste-efectividad en la evaluación económica de intervenciones sanitarias, Med Clin (Barc), 122, 423, 10.1016/S0025-7753(04)74260-8 Zimlichman, 2013, Health care-associated infections: a meta-analysis of costs and financial impact on the US health care system, JAMA Intern Med, 173, 2039, 10.1001/jamainternmed.2013.9763 Tansarli, 2013, Impact of antimicrobial multidrug resistance on inpatient care cost: an evaluation of the evidence, Expert Rev Anti Infect Ther, 11, 321, 10.1586/eri.13.4 Gandra, 2014, Economic burden of antibiotic resistance: how much do we really know?, Clin Microbiol Infect, 20, 973, 10.1111/1469-0691.12798 Perez, 2013, Integrating rapid pathogen identification and antimicrobial stewardship significantly decreases hospital costs, Arch Pathol Lab Med, 137, 1247, 10.5858/arpa.2012-0651-OA Perez, 2014, Integrating rapid diagnostics and antimicrobial stewardship improves outcomes in patients with antibiotic-resistant Gram-negative bacteremia, J Infect, 69, 216, 10.1016/j.jinf.2014.05.005 Patel, 2016, Cost analysis of implementing matrix-assisted laser desorption ionization-time of flight mass spectrometry plus real-time antimicrobial stewardship intervention for bloodstream infections, J Clin Microbiol, 55, 60, 10.1128/JCM.01452-16 Bauer, 2014, Review of rapid diagnostic tests used by antimicrobial stewardship programs, Clin Infect Dis, 59, S134, 10.1093/cid/ciu547 McElvania TeKippe, 2016, The added cost of rapid diagnostic testing and active antimicrobial stewardship: is it worth it?, J Clin Microbiol, 55, 20, 10.1128/JCM.02061-16 Gómez, 2014, Estudio de coste-efectividad de la espectrometría de masas (MALDI TOF) para la identificación de Candida spp. al nivel de especie y la adecuación del tratamiento en pacientes cone candidemia, Gest Eval Cost Sanit, 15, 457 National Institute for Health and Care Excellence. Available from: http://www.nice.org.uk [accessed 12.9.17]. Real Decreto-ley 9/2011, de 19 de agosto, de medidas para la mejora de la calidad y cohesión del sistema nacional de salud, de contribución a la consolidación fiscal, y de elevación del importe máximo de los avales del Estado para 2011. BOE n.° 200, 20 de agosto de 2011; Sec. I: p. 93143–68. Cabiedes Miragaya, 2012 Reglamento (UE) 2017/746 del Parlamento Europeo y del Consejo de 5 de abril de 2017 sobre los productos sanitarios para diagnóstico in vitro y por el que se derogan la Directiva 98/79/CE y la Decisión 2010/227/UE de la Comisión.