Echistatin inhibits pp72syk and pp125FAK phosphorylation in fibrinogen-adherent platelets

Biochimie - Tập 79 - Trang 769-773 - 1997
N. Staiano1, R. Della Morte1, C. Di Domenico1, S. Tafuri1, C. Squillacioti1, M.A. Belisario1, P. Di Natale1
1Dipartimento di Biochimica e Biotechnologie Mediche, Università di Napoli Federico II, Via S Pansini, 5, 80131 Naples, Italy

Tài liệu tham khảo

Gould, 1990, Disintegrins: a family of integrin inhibitory proteins from viper venoms, 195, 168 Dennis, 1990, Platelet glycoprotein llb-Illa protein antagonists from snake venoms: evidence for a family of platelet-aggregation inhibitors, 87, 2471 Scarborough, 1993, Characterization of the integrin specificities of disintegrins isolated from American pit viper venoms, J Biol Chem, 268, 1058, 10.1016/S0021-9258(18)54041-2 Soszka, 1991, Inhibition of murine melanoma cell-matrix adhesion and experimental metastasis by albolabrin, an RGD-containing peptide isolated from venom of Trimeresurus albolabris, Exp Cell Res, 196, 6, 10.1016/0014-4827(91)90449-5 Staiano, 1995, Echistatin inhibits the adhesion of murine melanoma cells to extracellular matrix components, Biochem Mol Biol Int, 35, 11 Calvete, 1994, Characterization of the cross-linking site of disintegrins albolabrin, bitistatin, echistatin, and cristostatin on isolated human platelet integrin GP IIb/IIIa, Biochem Biophys Res Commun, 202, 135, 10.1006/bbrc.1994.1903 Pfaff, 1996, Comparison of disintegrins with limited variation in the RGD loop in their binding to purified integrins αllbβ3, αyβ3 and α5β1 and in cell adhesion inhibition, Cell Adh Commun, 2, 491, 10.3109/15419069409014213 Clark, 1995, Integrins and signal transduction pathways: the road taken, Science, 268, 233, 10.1126/science.7716514 Clark, 1994, Structurally distinct disintegrins contortrostatin and multisquamatin differentially regulate platelet tyrosine phosphorylation, J Biol Chem, 269, 21940, 10.1016/S0021-9258(17)31737-4 Gan, 1988, Echistatin, a potent platelet aggregation inhibitor from the viper Echis carinatus, J Biol Chem, 263, 19827, 10.1016/S0021-9258(19)77710-2 Marcinkiewicz, 1996, Immunological characterization of eristostatin and echistatin binding sites on αllbβ3 and αvβ3 integrins, Biochem J, 317, 817, 10.1042/bj3170817 Staiano, 1997, Echistatin induces decrease of pp125FAK phosphorylation, disassembly of actin cytoskeleton and focal adhesions, and detachment of fibronectin-adherent melanoma cells, Eur J Cell Biol, 73, 298 Lu, 1994, Preferential antagonism of the interaction of the integrin αllbβ3 with immobilized glycoprotein ligands by snake-venom RGD (Arg-Gly-Asp) proteins, Biochem J, 304, 929, 10.1042/bj3040929 Bennett, 1979, Exposure of platelet fibrinogen receptors by ADP and epinephrine, J Clin Invest, 64, 1393, 10.1172/JCI109597 Timmons, 1989, Isolation of human platelets by albumin gradient and gel filtration, Methods Enzymol, 169, 11, 10.1016/0076-6879(89)69046-5 Sixma, 1977, The hemostatic plug, Semin Haematol, 14, 265 Fitzgerald, 1986, Platelet activation in unstable coronary disease, N Engl J Med, 315, 983, 10.1056/NEJM198610163151602 Calvete, 1994, Clues for understanding the structure and function of a prototypic human integrin: the platelet glycoprotein IIb/IIIa complex, Thromb Haemost, 72, 1, 10.1055/s-0038-1648803 Shattil, 1987, Induction of the fibrinogen receptor on human platelets by intracellular mediators, J Biol Chem, 262, 992, 10.1016/S0021-9258(19)75739-1 Sims, 1991, Effect of platelet activation on the conformation of the plasma glycorprotein IIb-IIIa, J Biol Chem, 266, 7345, 10.1016/S0021-9258(20)89452-6 Golden, 1990, Role of platelet membrane glycoprotein IIb-IIIa in agonist induced tyrosine phosphorylation of platelet proteins, J Cell Biol, 111, 3117, 10.1083/jcb.111.6.3117 Belisario, 1996, Inhibition of human platelet adhesion to immobilized extracellular matrix components by disintegrins, Fund Clin Pharm, 10, 164 Clark, 1994, Regulation of the protein tyrosine kinase pp72syk by platelet agonists and the integrin αllbβ3, J Biol Chem, 269, 28859, 10.1016/S0021-9258(19)61986-1 Taniguchi, 1993, Protein tyrosine kinase p72syk is activated by thrombin and is negatively regulated through Ca2+ mobilization in platelets, J Biol Chem, 268, 2277, 10.1016/S0021-9258(18)53767-4 Shattil, 1994, Tyrosine phosphorylation of pp125FAK in platelets requires coordinated signaling through integrin and agonist receptors, J Biol Chem, 269, 14738, 10.1016/S0021-9258(17)36687-5 Chung, 1997, Thrombospondin acts via integrin-associated protein to activate the platelet integrin αllbβ3, J Biol Chem, 272, 14740, 10.1074/jbc.272.23.14740 Coller, 1992, Antiplatelet agents in the prevention and therapy of thrombosis, Annu Rev Med, 43, 171, 10.1146/annurev.me.43.020192.001131 Coller, 1995, New antiplatelet agents: platelet GP IIb-IIIa antagonists, Thromb Haemost, 74, 302, 10.1055/s-0038-1642694 Cook, 1989, Inhibition of platelet hemostatic plug formation by trigramin, a novel RGD-peptide, Am J Physiol, 256, H1038 Holahan, 1991, Prevention of reocclusion following tissue-type plasminogen activator-induced thrombolysis by the RGD-containing peptide echistatin in a canine model of coronary thrombosis, Pharmacology, 42, 340, 10.1159/000138817 Shebusky, 1990, Acceleration of recombinant tissue-type plasminogen by the combination of heparin and the Arg-Gly-Asp-containing peptide bitistatin in a canine model of coronary thrembosis, Circulation, 82, 169, 10.1161/01.CIR.82.1.169 Yasuda, 1991, Kistrin, a polypeptide platelet GPIIb/IIIa receptor antagonist, enhances and sustains coronary arterial thrombolysis with tissue-type plasminogen activator in a canine preparation, Circulation, 83, 1038, 10.1161/01.CIR.83.3.1038