Ebselen: prospective therapy for cerebral ischaemia

Expert Opinion on Investigational Drugs - Tập 9 Số 3 - Trang 607-619 - 2000
Michael J. Parnham1, Helmut Sies2
1PLIVA d.d., Research & Development, Prilaz baruna Filipovica 25, HR-10 000, Zagreb, Croatia. [email protected]
2Institut für Physiologische Chemie I, Heinrich-Heine-Universität, Postfach 101007, D-40001, Düsseldorf, Germany. [email protected]

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Tài liệu tham khảo

10.1016/0024-3205(94)00392-0

10.1016/0140-6736(92)90347-6

10.1097/00003246-199903000-00045

TRAYSTMAN RJ, 1991, J. AppL Physiol., 71, 1185, 10.1152/jappl.1991.71.4.1185

10.1007/s000180050357

10.1345/aph.17350

10.1056/NEJM199512143332401

10.1016/0165-6147(96)10020-1

MOLLER A, 1984, I. Glutathione peroxidase-like activity in-vitro and antioxidant capacity of PZ 51 (ebselen). Biochem. Pharmacol., 33, 3235

WENDEL A, 1984, II. Activity PZ 51 in relation to glutathione peroxidase. Biochem. Pharmacol., 33, 3241

10.1016/0003-9861(92)90534-4

10.1016/0891-5849(93)90028-S

10.1021/tx950115u

10.1016/S0014-5793(96)01237-9

10.1016/S0014-5793(99)00073-3

10.1016/0006-2952(86)90376-X

10.1016/0006-2952(94)90224-0

10.1016/0306-3623(95)00003-J

PARNHAM MJ, 1991, Prog. Drug Res., 36, 9

10.1002/cber.19240570703

10.1002/bscb.19870961006

CANTINEAU R, 1986, A novel biologically active organo-selenium compound. J. Label]. Comp. Radiopharmaceut., 23, 59

10.1002/bscb.19870960506

10.1021/jo00273a035

10.1021/ja00197a065

10.1016/0006-2952(92)90245-E

10.1517/13543784.8.7.1017

MILLS GC, 1957, I. Glutathioneperoxidase, an erythrocyte enzyme which protects hemoglobin from oxidase breakdown. J. Biol. Chem., 229, 189

10.1016/0014-5793(73)80755-0

10.1126/science.179.4073.588

10.1016/0304-4165(85)90182-5

TAKAHASHI K, 1990, J. Biochem., 108, 145, 10.1093/oxfordjournals.jbchem.a123172

10.1016/S0891-5849(99)00173-2

10.1016/0006-2952(88)90591-6

10.1016/0009-2797(92)90122-2

WILLER A, 1985, IV. Protective glutathione-dependent effect of PZ 51 (ebselen) against ADP-Fe induced lipid peroxidation in isolated hepatocytes. Biochem. Pharmacol., 34, 1185

HAENEN GRMM, DE ROOIJ BM, VERMEULEN NPE, BAST A, 1990, Dihydrolipoate is a better cofactor than glutathione in the peroxidase activity of ebselen. Mot. Pharmacol., 37, 412

10.1021/tx950135w

10.3109/10715768609088070

10.3109/10715769009149892

10.1016/0006-2952(92)90035-H

10.1016/0006-2952(87)90617-4

PARNHAM MJ, 1985, Adv. In/Yarn. Res., 10, 397

10.1517/13543784.5.7.861

10.1016/0003-9861(79)90038-9

SCHALKWIJK J, 1986, Effects of a single inflammatory mediator on (perDarticular tissues. Arthr. Rheum., 29, 532

10.1007/BF01991237

HARTUNG HP, 1986, Ann. Neurol., 20, 168

10.1111/j.1432-2277.1997.tb00548.x

HOSHIDA S, 1994, Am. J. Physiol., 267, H2342–H2347

10.1016/S0891-5849(97)00388-2

10.1016/0006-2952(96)00084-6

TIEGS G, 1998, J. Pharmacol. Exp. Ther., 287, 1098

10.1016/0304-3940(94)11226-9

10.1038/sj.bjp.0701426

10.1097/00006123-199902000-00073

TAN YX, 1997, Chung Kuo Yao Li Hsueh Pao, 18, 201

WATANABE T, 1997, Neurol. Res., 19, 563, 10.1080/01616412.1997.11740859

10.1007/BF01972806

TARINO JZ, 1986, Nutr. Reports Int., 33, 299

MOLLER A, 1988, VII. Biotransformation of ebselen in perfused rat liver. Biochem. Pharmacol., 37, 1103

10.3109/00498258809042259

10.1016/0006-2952(74)90351-7

10.3987/R-1986-11-3027

10.1016/0006-2952(94)90150-3

NIKAWA T, 1994, Biochem. Mol. Biol. Int., 32, 291

10.1016/0006-2952(94)90411-1

10.1021/tx00026a004

YAMAGUCHI T, 1998, A placebo-controlled, double-blind clinical trial. Stroke, 29, 12

10.1097/00006123-199802000-00038

10.1159/000015908