Early Colon Screening of Adult Patients With Cystic Fibrosis Reveals High Incidence of Adenomatous Colon Polyps

Farrell, 2008, The prevalence of cystic fibrosis in the European Union., J Cyst Fibros, 7, 450, 10.1016/j.jcf.2008.03.007

Salvatore, 2012, . An overview of international literature from cystic fibrosis registries. Part 4: Update 2011., J Cyst Fibros, 11, 480, 10.1016/j.jcf.2012.07.005

Parkins, 2011, . Changing epidemiology and clinical issues arising in an ageing cystic fibrosis population., Ther Adv Respir Dis, 5, 105, 10.1177/1753465810386051

Wilschanski, 2007, Patterns of GI disease in adulthood associated with mutations in the CFTR gene., Gut, 56, 1153, 10.1136/gut.2004.062786

Neglia, 1995, . The risk of cancer among patients with cystic fibrosis. Cystic Fibrosis and Cancer Study Group., N Engl J Med, 332, 494, 10.1056/NEJM199502233320803

Hernandez-Jimenez, 2008, Colon cancer in cystic fibrosis patients: is this a growing problem J Cyst Fibros., , 7, 343

Alexander, 2008, . The risk of gastrointestinal malignancies in cystic fibrosis: case report of a patient with a near obstructing villous adenoma found on colon cancer screening and Barretts esophagus., J Cyst Fibros, 7, 1, 10.1016/j.jcf.2007.07.005

Meyer, 2011, . Colon cancer in lung transplant recipients with CF: increased risk and results of screening., J Cyst Fibros, 10, 366, 10.1016/j.jcf.2011.05.003

Maisonneuve, 2003, . Cancer risk in nontransplanted and transplanted cystic fibrosis patients: a 10-year study., J Natl Cancer Inst, 95, 381, 10.1093/jnci/95.5.381

Maisonneuve, 2013, . Cancer risk in cystic fibrosis: a 20-year nationwide study from the United States., J Natl Cancer Inst, 105, 122, 10.1093/jnci/djs481

Johannesson, 2009, . Cancer risk among patients with cystic fibrosis and their first-degree relatives., Int J Cancer, 125, 2953, 10.1002/ijc.24679

Winawer, 1993, . Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study Workgroup., N Engl J Med, 329, 1977, 10.1056/NEJM199312303292701

Espey, 2007, . Annual report to the nation on the status of cancer, 1975-2004, featuring cancer in American Indians and Alaska Natives., Cancer, 110, 2119, 10.1002/cncr.23044

Selby, 1992, . A case-control study of screening sigmoidoscopy and mortality from colorectal cancer., N Engl J Med, 326, 653, 10.1056/NEJM199203053261001

Hardcastle, 1996, . Randomised controlled trial of faecal-occult-blood screening for colorectal cancer., Lancet, 348, 1472, 10.1016/S0140-6736(96)03386-7

Kronborg, 1996, . Randomised study of screening for colorectal cancer with faecal-occult-blood test., Lancet, 348, 1467, 10.1016/S0140-6736(96)03430-7

Mandel, 2000, . The effect of fecal occult-blood screening on the incidence of colorectal cancer., N Engl J Med, 343, 1603, 10.1056/NEJM200011303432203

Zauber, 2012, . Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths., N Engl J Med, 366, 687, 10.1056/NEJMoa1100370

Levin, 2008, . Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology., Gastroenterology, 134, 1570, 10.1053/j.gastro.2008.02.002

Rex, 2009, . American College of Gastroenterology guidelines for colorectal cancer screening 2009 corrected., Am J Gastroenterol, 104, 739, 10.1038/ajg.2009.104

McCashland, 2001, . Gender differences in colorectal polyps and tumors., Am J Gastroenterol, 96, 882, 10.1111/j.1572-0241.2001.03638.x

Regula, 2006, . Colonoscopy in colorectal-cancer screening for detection of advanced neoplasia., N Engl J Med, 355, 1863, 10.1056/NEJMoa054967

Brenner, 2007, . Gender differences in colorectal cancer: implications for age at initiation of screening., Br J Cancer, 96, 828, 10.1038/sj.bjc.6603628

El Sayed, 2003, . A randomized single-blind trial of whole versus split-dose polyethylene glycol-electrolyte solution for colonoscopy preparation., Gastrointest Endosc, 58, 36, 10.1067/mge.2003.318

Belsey, 2012, . Meta-analysis: the relative efficacy of oral bowel preparations for colonoscopy 1985-2010., Aliment Pharmacol Ther, 35, 222, 10.1111/j.1365-2036.2011.04927.x

Imperiale, 2002, . Results of screening colonoscopy among persons 40 to 49 years of age., N Engl J Med, 346, 1781, 10.1056/NEJM200206063462304

Hong, 2010, . Prevalence and risk of colorectal neoplasms in asymptomatic, average-risk screenees 40 to 49 years of age., Gastrointest Endosc, 72, 480, 10.1016/j.gie.2010.06.022

Thoma, 2011, . Detection of colorectal neoplasia by colonoscopy in average-risk patients age 40-49 versus 50-59 years., Dig Dis Sci, 56, 1503, 10.1007/s10620-011-1565-6

Starr, 2009, . A transposon-based genetic screen in mice identifies genes altered in colorectal cancer., Science, 323, 1747, 10.1126/science.1163040

Mehta, 2008, Cystic fibrosis as a bowel cancer syndrome and the potential role of CK2., Mol Cell Biochem, 316, 169, 10.1007/s11010-008-9815-4

Kerbiriou, 2009, . The calpain, caspase 12, caspase 3 cascade leading to apoptosis is altered in F508del-CFTR expressing cells., PLoS One, 4, e8436, 10.1371/journal.pone.0008436

Garcia, 2009, Quinton PM. Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator-dependent bicarbonate secretion., J Clin Invest, 119, 2613, 10.1172/JCI38662

Voynow, 1998, Mucin gene expression (MUC1, MUC2, and MUC55AC) in nasal epithelial cells of cystic fibrosis, allergic rhinitis, and normal individuals., Lung, 176, 345, 10.1007/PL00007616

Kreda, 2012, CFTR mucins, and mucus obstruction in cystic fibrosis., Cold Spring Harb Perspect Med, 2, a009589, 10.1101/cshperspect.a009589

Velcich, 2002, . Colorectal cancer in mice genetically deficient in the mucin Muc2., Science, 295, 1726, 10.1126/science.1069094

Norkina, 2004, Bacterial overgrowth in the cystic fibrosis transmembrane conductance regulator null mouse small intestine., Infect Immun, 72, 6040, 10.1128/IAI.72.10.6040-6049.2004

Gallagher, 2001, Proliferation, not apoptosis, alters epithelial cell migration in small intestine of CFTR null mice., Am J Physiol Gastrointest Liver Physiol, 281, G681, 10.1152/ajpgi.2001.281.3.G681

Abreu, 2010, Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function., Nat Rev Immunol, 10, 131, 10.1038/nri2707

Rakoff-Nahoum, 2009, Toll-like receptors and cancer., Nat Rev Cancer, 9, 57, 10.1038/nrc2541

Arthur, 2012, . Intestinal inflammation targets cancer-inducing activity of the microbiota., Science, 338, 120, 10.1126/science.1224820

Deeb, 2007, Vitamin D signalling pathways in cancer: potential for anticancer therapeutics., Nat Rev Cancer, 7, 684, 10.1038/nrc2196

Smith, 2009, . Trans-fatty acids and cancer: a mini-review., Br J Nutr, 102, 1254, 10.1017/S0007114509991437