EGFR signaling is required for regenerative proliferation in the cochlea: Conservation in birds and mammals

Alvarado, 2011, An RNA interference-based screen of transcription factor genes identifies pathways necessary for sensory regeneration in the avian inner ear, J. Neurosci., 31, 4535, 10.1523/JNEUROSCI.5456-10.2011 Bermingham-McDonogh, 2006, Expression of Prox1 during mouse cochlear development, J. Comp. Neurol., 496, 172, 10.1002/cne.20944 Brignull, 2009, Feathers and fins: non-mammalian models for hair cell regeneration, Brain Res., 1277, 12, 10.1016/j.brainres.2009.02.028 Burns, 2008, Reinforcement of cell junctions correlates with the absence of hair cell regeneration in mammals and its occurrence in birds, J. Comp. Neurol., 511, 396, 10.1002/cne.21849 Busse, 2000, Reversible G(1) arrest induced by inhibition of the epidermal growth factor receptor tyrosine kinase requires up-regulation of p27(KIP1) independent of MAPK activity, J. Biol. Chem., 275, 6987, 10.1074/jbc.275.10.6987 Casciola-Rosen, 1996, Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: Implications for coagulation events and antigenic spread in systemic lupus erythematosus, P.N.A.S., 93, 1624, 10.1073/pnas.93.4.1624 Chardin, 1995, Regeneration and mammalian auditory hair cells, Science, 267, 707, 10.1126/science.7839151 Chen, 1999, p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti, Development, 126, 1581, 10.1242/dev.126.8.1581 Clausen, 1986, Cell cycle progression kinetics of regenerating mouse epidermal cells: an in vivo study combining DNA flow cytometry, cell sorting, and [3H]dThd autoradiography, J. Invest. Dermatol., 86, 402, 10.1111/1523-1747.ep12285672 Corwin, 1988, Regeneration of sensory hair cells after acoustic trauma, Science, 240, 1772, 10.1126/science.3381100 Daudet, 1998, Characterization of atypical cells in the juvenile rat organ of corti after aminoglycoside ototoxicity, J. Comp. Neurol., 401, 145, 10.1002/(SICI)1096-9861(19981116)401:2<145::AID-CNE1>3.0.CO;2-C Daudet, 2002, Transforming growth factor-alpha-induced cellular changes in organotypic cultures of juvenile, amikacin-treated rat organ of corti, J. Comp. Neurol., 442, 6, 10.1002/cne.1418 Diensthuber, 2009, Stem/progenitor cells derived from the cochlear sensory epithelium give rise to spheres with distinct morphologies and features, J. Assoc. Res. Otolaryngol., 10, 173, 10.1007/s10162-009-0161-3 Doetzlhofer, 2004, In vitro growth and differentiation of mammalian sensory hair cell progenitors: a requirement for EGF and periotic mesenchyme, Dev. Biol., 272, 432, 10.1016/j.ydbio.2004.05.013 Fero, 1996, A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice, Cell, 85, 733, 10.1016/S0092-8674(00)81239-8 Gestwa, 1999, Differential expression of trkB.T1 and trkB.T2, truncated trkC, and p75(NGFR) in the cochlea prior to hearing function, J. Comp. Neurol., 414, 33, 10.1002/(SICI)1096-9861(19991108)414:1<33::AID-CNE3>3.0.CO;2-M Gu, 2007, Proliferative responses to growth factors decline rapidly during postnatal maturation of mammalian hair cell epithelia, Eur. J. Neurosci., 25, 1363, 10.1111/j.1460-9568.2007.05414.x Hume, 2003, ErbB expression: the mouse inner ear and maturation of the mitogenic response to heregulin, J. Assoc. Res. Otolaryngol., 4, 422, 10.1007/s10162-002-3008-8 Jones, 1998, Binding interaction of the heregulinbeta egf domain with ErbB3 and ErbB4 receptors assessed by alanine scanning mutagenesis, J. Biol. Chem., 273, 11667, 10.1074/jbc.273.19.11667 Kim, 1997, cAMP-dependent protein kinase A is required for Schwann cell growth: interactions between the cAMP and neuregulin/tyrosine kinase pathways, J. Neurosci. Res., 49, 236, 10.1002/(SICI)1097-4547(19970715)49:2<236::AID-JNR12>3.0.CO;2-Z Kubota, 2000, EGF receptor attenuates Dpp signaling and helps to distinguish the wing and leg cell fates in Drosophila, Development, 127, 3769, 10.1242/dev.127.17.3769 Kuntz, 1998, Transforming growth factor alpha with insulin stimulates cell proliferation in vivo in adult rat vestibular sensory epithelium, J. Comp. Neurol., 399, 413, 10.1002/(SICI)1096-9861(19980928)399:3<413::AID-CNE9>3.0.CO;2-3 Li, 2005, BMP4 signaling is involved in the generation of inner ear sensory epithelia, BMC Dev. Biol., 5, 16, 10.1186/1471-213X-5-16 Livak, 2001, Analysis of relative gene expression data using real-time quantitative PCR and the 2(−Delta Delta C(T)) Method, Methods, 25, 402, 10.1006/meth.2001.1262 Lou, 2007, Multipotent stem cells from the young rat inner ear, Neurosci. Lett., 416, 28, 10.1016/j.neulet.2006.12.061 Lowenheim, 1999, Gene disruption of p27(Kip1) allows cell proliferation in the postnatal and adult organ of corti, Proc. Natl. Acad. Sci. U. S. A., 96, 4084, 10.1073/pnas.96.7.4084 Lumpkin, 2003, Math1-driven GFP expression in the developing nervous system of transgenic mice, Gene Expr. Patterns, 3, 389, 10.1016/S1567-133X(03)00089-9 McCullar, 2010, Activin potentiates proliferation in mature avian auditory sensory epithelium, J. Neurosci., 30, 478, 10.1523/JNEUROSCI.5154-09.2010 Michalopoulos, 1982, Liver regeneration studies with rat hepatocytes in primary culture, Cancer Res., 42, 4673 Monje, 2008, Protein kinase A-mediated gating of neuregulin-dependent ErbB2-ErbB3 activation underlies the synergistic action of cAMP on Schwann cell proliferation, J. Biol. Chem., 283, 34087, 10.1074/jbc.M802318200 Montcouquiol, 2001, Brief treatments with forskolin enhance s-phase entry in balance epithelia from the ears of rats, J. Neurosci., 21, 974, 10.1523/JNEUROSCI.21-03-00974.2001 Montcouquiol, 2001, J. Neurosci., 21, 570, 10.1523/JNEUROSCI.21-02-00570.2001 Navaratnam, 1996, Proliferation in the auditory receptor epithelium mediated by a cyclic AMP-dependent signaling pathway, Nat. Med., 2, 1136, 10.1038/nm1096-1136 Oesterle, 1993, Hair-cell regeneration in organ cultures of the postnatal chicken inner ear, Hear. Res., 70, 85, 10.1016/0378-5955(93)90054-5 Oiticica, 2010, Retention of progenitor cell phenotype in otospheres from guinea pig and mouse cochlea, J. Transl. Med., 8, 119, 10.1186/1479-5876-8-119 Osherov, 1994, Epidermal-growth-factor-dependent activation of the src-family kinases, Eur. J. Biochem., 225, 1047, 10.1111/j.1432-1033.1994.1047b.x Richardson, 1997, Myosin VIIA is required for aminoglycoside accumulation in cochlear hair cells, J. Neurosci., 17, 9506, 10.1523/JNEUROSCI.17-24-09506.1997 Romand, 1999, Effects of growth factors on the hair cells after ototoxic treatment of the neonatal mammalian cochlea in vitro, Brain Res., 825, 46, 10.1016/S0006-8993(99)01211-1 Ruben, 1967, Development of the inner ear of the mouse: a radioautographic study of terminal mitoses, Acta Otolaryngol. Suppl., 220, 1 Ryals, 1988, Hair cell regeneration after acoustic trauma in adult Coturnix quail, Science, 240, 1774, 10.1126/science.3381101 Savary, 2007, Distinct population of hair cell progenitors can be isolated from the postnatal mouse cochlea using side population analysis, Stem Cells, 25, 332, 10.1634/stemcells.2006-0303 Schlessinger, 2005, Epidermal growth factor receptor pathway, vol. 2010 Shang, 2010, Supporting cell division is not required for regeneration of auditory hair cells after ototoxic injury in vitro, J. Assoc. Res. Otolaryngol., 11, 203, 10.1007/s10162-009-0206-7 Shin, 2003, The chemical synthesis and binding affinity to the EGF receptor of the EGF-like domain of heparin-binding EGF-like growth factor (HB-EGF), J. Pept. Sci., 9, 244, 10.1002/psc.450 Stankovic, 2004, Survival of adult spiral ganglion neurons requires erbB receptor signaling in the inner ear, J. Neurosci., 24, 8651, 10.1523/JNEUROSCI.0733-04.2004 Stephens, 1968, A case of gentamicin accentuated hearing loss, J. Laryngol. Otol., 82, 803, 10.1017/S0022215100069486 Stone, 2004, cProx1 immunoreactivity distinguishes progenitor cells and predicts hair cell fate during avian hair cell regeneration, Dev. Dyn., 230, 597, 10.1002/dvdy.20087 Tucci, 1990, Physiologic status of regenerated hair cells in the avian inner ear following aminoglycoside ototoxicity, Otolaryngol. Head Neck Surg., 103, 443, 10.1177/019459989010300317 White, 2006, Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells, Nature, 441, 984, 10.1038/nature04849 Witte, 2001, Regeneration in avian hair cell epithelia: identification of intracellular signals required for S-phase entry, Eur. J. Neurosci., 14, 829, 10.1046/j.0953-816x.2001.01695.x Xu, 2010, Receptor type protein tyrosine phosphatase-kappa mediates cross-talk between transforming growth factor-beta and epidermal growth factor receptor signaling pathways in human keratinocytes, Mol. Biol. Cell., 21, 29, 10.1091/mbc.E09-08-0710 Yamashita, 1995, Induction of cell proliferation in mammalian inner-ear sensory epithelia by transforming growth factor alpha and epidermal growth factor, Proc. Natl. Acad. Sci. U. S. A., 92, 3152, 10.1073/pnas.92.8.3152 Yu, 2010, In vivo proliferation of postmitotic cochlear supporting cells by acute ablation of the retinoblastoma protein in neonatal mice, J. Neurosci., 30, 5927, 10.1523/JNEUROSCI.5989-09.2010 Zhai, 2005, Isolation and culture of hair cell progenitors from postnatal rat cochleae, J. Neurobiol., 65, 282, 10.1002/neu.20190