EGF and Its Receptor: Historical Perspective

S. Cohen (1960). Purification of a nerve growth-promoting protein from the mouse salivary gland and its neuro-cytotoxic antiserum. Proc. Natl. Acad. Sci. U.S.A. 46:302–311. S. Cohen (1962). Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the newborn animal. J. Biol. Chem. 237:1555–1562. S. Cohen and G. A. Elliott (1963). The stimulation of epidermal keratinization by a protein isolated from the submaxillary gland to the mouse. J. Invest. Dermatol. 40:1–5. S. Cohen (1965). The stimulation of epidermal proliferation by a specific protein (EGF). Dev. Biol. 12:394–407. S. Cohen and J. M. Taylor (1974). Epidermal growth factor: chemical and biological characterization. Recent Prog. Horm. Res. 30:533–550. C. R. Savage, Jr. and S. Cohen (1974). Recent studies on the chemistry and biology of epidermal growth factor. Recent Prog. Horm. Res. 30:551–574. C. R. Savage, Jr., T. Inagai, and S. Cohen (1972). The primary structure of epidermal growth factor. J. Biol. Chem. 247:7612–7621. C. R. Savage, Jr., J. H. Hash, and S. Cohen (1973). Epidermal growth factor: location of disulfide bonds. J. Biol. Chem. 248:7669–7672. S. Cohen and G. Carpenter (1975). Human epidermal growth factor: isolation and chemical and biological properties. Proc. Natl. Acad. Sci. U.S.A. 72:1317–1321. H. Gregory (1975). Isolation and structure of urogastrone and its relationship to epidermal growth factor. Nature London 257:325–327. G. Carpenter, K. J. Lembach, M. M. Morrison, and S. Cohen (1975). Characterization of the binding of 125I-labeled epidermal growth factor to human fibroblasts. J. Biol. Chem. 250:4297–4304. G. Carpenter and S. Cohen (1976). Human epidermal growth factor and the proliferation of human fibroblasts. J. Cell Biol. 71:159–171. G. J. Todaro, J. E. DeLarco, and S. Cohen (1976). Transformation by murine and feline sarcoma viruses specifically blocks binding of epidermal growth factor to cells. Nature London 264:26–31. H. T. Haigler, J. F. Ash, S. J. Singer, and S. Cohen (1978). Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431. Proc. Natl. Acad. Sci. U.S.A. 75:3317–3321. P. Gordon, J.-L. Carpentier, S. Cohen, and L. Orci (1978). Epidermal growth factor: morphological demonstration of binding, internalization and lysosomal association in human fibroblasts. Proc. Natl. Acad. Sci. U.S.A. 75:5025–5029. H. T. Haigler, J. A. McKanna, and S. Cohen (1979). Rapid stimulation of pinocytosis in human carcinoma cells A-431 by epidermal growth factor. J. Cell Biol. 81:382–395. J. A. McKanna, H. T. Haigler, and S. Cohen (1979). Hormone receptor topology and dynamics: morphological analysis using ferritin-labeled epidermal growth factor. Proc. Natl. Acad. Sci. U.S.A. 76:5689–5693. H. Ushiro and S. Cohen (1980). Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes. J. Biol. Chem. 255:8363–8365. S. Cohen, H. Urhiro, C. M. Stoscheck, and M. Chinkers (1982). A native 170,000 epidermal growth factor receptor-kinase complex from shed plasma. J. Biol. Chem. 257:1523–1531. S. A. Buhrow, S. Cohen, and J. V. Staros (1982). Affinity labeling of the protein kinase associated with the epidermal growth factor receptor in membrane vesicles from A-431 cells. J. Biol. Chem. 257:4019–4022.