EGF Receptor Signaling Triggers Recruitment of Drosophila Sense Organ Precursors by Stimulating Proneural Gene Autoregulation

Albagli, 1996, Function of ETS genes is conserved between vertebrates and Drosophila, Mech. Dev, 59, 29, 10.1016/0925-4773(96)00568-0 Alvarez, 2003, pannier and pointedP2 act sequentially to regulate Drosophila heart development, Development, 130, 3015, 10.1242/dev.00488 Barolo, 2000, GFP and beta-galactosidase transformation vectors for promoter/enhancer analysis in Drosophila, Biotechniques, 29, 726, 10.2144/00294bm10 Berset, 2001, Notch inhibition of RAS signalling through MAP kinase phosphatase LIP-1 during C. elegans vulval development, Science, 291, 1055, 10.1126/science.1055642 Brewster, 1995, Origin and specification of type II sensory neurons in Drosophila, Development, 121, 2923, 10.1242/dev.121.9.2923 Chien, 1996, Neuronal type information encoded in the basic-helix-loop-helix domain of proneural genes, Proc. Natl. Acad. Sci. USA, 93, 13239, 10.1073/pnas.93.23.13239 Cubas, 1991, Proneural clusters of achaete-scute expression and the generation of sensory organs in the Drosophila wing disc, Genes Dev, 5, 996, 10.1101/gad.5.6.996 Culı́, 1998, Proneural gene self-stimulation in neural precursors, Genes Dev, 12, 2036, 10.1101/gad.12.13.2036 Dumstrei, 1998, EGFR signalling is required for the differentiation and maintenance of neural progenitors along the dorsal midline of the Drosophila embryonic head, Development, 125, 3417, 10.1242/dev.125.17.3417 Elstob, 2001, spalt-dependent switching between two cell fates that are induced by the Drosophila EGF receptor, Development, 128, 723, 10.1242/dev.128.5.723 Fitzsimmons, 1996, Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a B-cell-specific promoter, Genes Dev, 10, 2198, 10.1101/gad.10.17.2198 Flores, 2000, Combinatorial signaling in the specification of unique cell fates, Cell, 103, 75, 10.1016/S0092-8674(00)00106-9 Freeman, 1997, Cell determination strategies in the Drosophila eye, Development, 124, 261, 10.1242/dev.124.2.261 Gabay, 1996, EGF receptor signaling induces pointed P1 transcription and inactivates Yan protein in the Drosophila embryonic ventral ectoderm, Development, 122, 3355, 10.1242/dev.122.11.3355 Gabay, 1997, In situ activation pattern of Drosophila EGF receptor pathway during development, Science, 277, 1103, 10.1126/science.277.5329.1103 Giagtzoglou, 2003, Two modes of recruitment of E(spl) repressors onto target genes, Development, 130, 259, 10.1242/dev.00206 Goetz, 2000, Auto-inhibition of Ets-1 is counteracted by DNA binding cooperativity with core-binding factor alpha2, Mol. Cell. Biol, 20, 81, 10.1128/MCB.20.1.81-90.2000 Granderath, 2000, gcm and pointed synergistically control glial transcription of the Drosophila gene loco, Mech. Dev, 91, 197, 10.1016/S0925-4773(99)00304-4 Halfon, 2000, Ras pathway specificity is determined by the integration of multiple signal-activated and tissue-restricted transcription factors, Cell, 103, 63, 10.1016/S0092-8674(00)00105-7 Jafar-Nejad, 2003, Senseless acts as a binary switch during sensory organ precursor selection, Genes Dev, 17, 2966, 10.1101/gad.1122403 Jarman, 1998, The specificity of proneural genes in determining Drosophila sense organ identity, Mech. Dev, 76, 117, 10.1016/S0925-4773(98)00116-6 Jarman, 1993, atonal is a proneural gene that directs chordotonal organ formation in the Drosophila peripheral nervous system, Cell, 73, 1307, 10.1016/0092-8674(93)90358-W Kauffmann, 1996, Ras1 signaling and transcriptional competence in the R7 cell of Drosophila, Genes Dev, 10, 2167, 10.1101/gad.10.17.2167 Kodandapani, 1996, A new pattern for helix-turn-helix recognition revealed by the PU.1 ETS-domain-DNA complex, Nature, 380, 456, 10.1038/380456a0 Ma, 1994, Crystal structure of MyoD bHLH-DNA complex, Cell, 77, 451, 10.1016/0092-8674(94)90159-7 Maloof, 1998, The Hox gene lin-39 is required during C. elegans vulval induction to select the outcome of Ras signalling, Development, 125, 181, 10.1242/dev.125.2.181 Mann, 2002, Molecular mechanisms of selector gene function and evolution, Curr. Opin. Genet. Dev, 12, 592, 10.1016/S0959-437X(02)00344-1 Nakada, 2004, Distinct domains within Mash1 and Math1 are required for function in neuronal differentiation versus neuronal cell-type specification, Development, 131, 1319, 10.1242/dev.01008 Nolo, 2000, Senseless, a Zn finger transcription factor, is necessary and sufficient for sensory organ development in Drosophila, Cell, 102, 349, 10.1016/S0092-8674(00)00040-4 Okabe, 1997, Two-step induction of chordotonal organ precursors in Drosophila embryogenesis, Development, 124, 1045, 10.1242/dev.124.5.1045 O'Neill, 1994, The activities of 2 Ets-related transcription factors required for Drosophila eye development are modulated by the Ras/Mapk pathway, Cell, 78, 137, 10.1016/0092-8674(94)90580-0 Powell, 2004, The proneural proteins Atonal and Scute regulate neural target genes through different E-box binding sites, Mol. Cell. Biol, in press Rawlins, 2003, Echinoid limits R8 photoreceptor specification by inhibiting inappropriate EGF receptor signalling within R8 equivalence groups, Development, 130, 3715, 10.1242/dev.00602 Rebay, 1995, Yan functions as a general inhibitor of differentiation and is negatively regulated by activation of the Ras1/Mapk pathway, Cell, 81, 857, 10.1016/0092-8674(95)90006-3 Rogge, 1995, The role of yan in mediating choice between cell division and differentiation, Development, 121, 3947, 10.1242/dev.121.12.3947 Rohrbaugh, 2002, Notch activation of yan expression is antagonized by RTK/Pointed signaling in the Drosophila eye, Curr. Biol, 12, 576, 10.1016/S0960-9822(02)00743-1 Rusten, 2001, spalt modifies EGFR-mediated induction of chordotonal precursors in the embryonic PNS of Drosophila promoting the development of oenocytes, Development, 128, 711, 10.1242/dev.128.5.711 Sharma, 2002, pPTGAL, a convenient Gal4 P-element vector for testing expression of enhancer fragments in Drosophila, Genesis, 34, 115, 10.1002/gene.10127 Sieweke, 1998, Cooperative interaction of Ets-1 with USF-1 required for HIV-1 enhancer activity in T cells, EMBO J, 17, 1728, 10.1093/emboj/17.6.1728 Skeath, 1991, Regulation of achaete-scute gene expression and sensory organ formation in the Drosophila wing, Genes Dev, 5, 984, 10.1101/gad.5.6.984 Sun, 1998, Transcriptional regulation of atonal during development of the Drosophila peripheral nervous system, Development, 125, 3731, 10.1242/dev.125.18.3731 Van Doren, 1992, Spatial regulation of proneural gene activity, Genes Dev, 6, 2592, 10.1101/gad.6.12b.2592 Verger, 2002, When ETS transcription factors meet their partners, Bioessays, 24, 362, 10.1002/bies.10068 Xu, 2000, Overlapping activators and repressors delimit transcriptional response to receptor tyrosine kinase signals in the Drosophila eye, Cell, 103, 87, 10.1016/S0092-8674(00)00107-0 zur Lage, 1999, Antagonism of EGFR and Notch signalling in the reiterative recruitment of Drosophila adult chordotonal sense organ precursors, Development, 126, 3149, 10.1242/dev.126.14.3149 zur Lage, 1997, Requirement for EGF receptor signalling in neural recruitment during formation of Drosophila chordotonal sense organ clusters, Curr. Biol, 7, 166, 10.1016/S0960-9822(97)70087-3