EARS2 significantly coexpresses with PALB2 in breast and pancreatic cancer

Antoniou, 2014, Breast-cancer risk in families with mutations in PALB2, N. Engl. J. Med., 371, 497, 10.1056/NEJMoa1400382 Li, 2018, High expression of PALB2 predicts poor prognosis in patients with advanced breast cancer, FEBS Open Bio, 8, 56, 10.1002/2211-5463.12356 Vagena, 2019, PALB2 c.2257C>T truncating variant is a Greek founder and is associated with high breast cancer risk, J. Hum. Genet., 64, 767, 10.1038/s10038-019-0612-6 Lucas, 2014, BRCA1 and BRCA2 germline mutations are frequently demonstrated in both high-risk pancreatic cancer screening and pancreatic cancer cohorts, Cancer, 120, 1960, 10.1002/cncr.28662 Zhen, 2015, BRCA1, BRCA2, PALB2, and CDKN2A mutations in familial pancreatic cancer: a PACGENE study, Genet. Med., 17, 569, 10.1038/gim.2014.153 Canto, 2020, Surgical outcomes after pancreatic resection of screening-detected lesions in individuals at high risk for developing pancreatic cancer, J. Gastrointest. Surg., 24, 1101, 10.1007/s11605-019-04230-z PALB2. The human protein atlas https://www.proteinatlas.org/ENSG00000083093-PALB2/pathology retrieved 19 August 2021. Hofstatter, 2011, PALB2 mutations in familial breast and pancreatic cancer, Fam. Cancer, 10, 225, 10.1007/s10689-011-9426-1 Gao, 2013, Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal, Sci. Signal, 6, l1, 10.1126/scisignal.2004088 Shahriyari, 2017, Effect of Normalization Methods On the Performance of Supervised Learning Algorithms Applied to HTSeq-FPKM-UQ Data sets: 7SK RNA Expression As a Predictor of Survival in Patients With Colon Adenocarcinoma Goldman, 2020, Visualizing and interpreting cancer genomics data via the Xena platform, Nat. Biotechnol., 10.1038/s41587-020-0546-8 Pontén, 2008, The Human Protein Atlas—A tool for pathology, The Journal of Pathology: A Journal of the Pathological Society of Great Britain and Ireland, 216, 387, 10.1002/path.2440 Uhlen, 2017, A pathology atlas of the human cancer transcriptome, Science, 357, eaan2507, 10.1126/science.aan2507 Thissen, 2002, Quick and easy implementation of the Benjamini-Hochberg procedure for controlling the false positive rate in multiple comparisons, J. Educ. Behav. Stat., 27, 77, 10.3102/10769986027001077 Goldman M., Craft B., Zhu J., Haussler D. (2017) The UCSC Xena system for cancer genomics data visualization and interpretation. Annual Meeting Proceedings AACR. Pereira, 2016, The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes, Nat. Commun., 7, 11479, 10.1038/ncomms11479 Bailey, 2016, Genomic analyses identify molecular subtypes of pancreatic cancer, Nature, 531, 47, 10.1038/nature16965 Hu, 2018, Association between inherited germline mutations in cancer predisposition genes and risk of pancreatic cancer, JAMA, 319, 2401, 10.1001/jama.2018.6228 Şahin, 2016, Leukoencephalopathy with thalamus and brainstem involvement and high lactate caused by novel mutations in the EARS2 gene in two siblings, J. Neurol. Sci., 365, 54, 10.1016/j.jns.2016.04.008 Schubert, 2020, Molecular basis of Leigh syndrome: a current look, Orphanet. J. Rare Dis., 15 EARS2. The human protein atlas https://www.proteinatlas.org/ENSG00000103356-EARS2/pathology retrieved 19 August 2021. Cui, 2021, Identification of metabolic-associated genes for the prediction of colon and rectal adenocarcinoma, Onco Targets Ther., 14, 2259, 10.2147/OTT.S297134 Pu, 2020, Research-based PAM50 signature and long-term breast cancer survival, Breast Cancer Res. Treat., 179, 197, 10.1007/s10549-019-05446-y Ge, 2021, PALB2 upregulation is associated with a poor prognosis in pancreatic ductal adenocarcinoma, Oncol. Lett., 21, 224, 10.3892/ol.2021.12485 Satyananda, 2021, High BRCA2 gene expression is associated with aggressive and highly proliferative breast cancer, Ann. Surg. Oncol.