Dysimmunity in common variable immunodeficiency is associated with alterations in oral, respiratory, and intestinal microbiota

Clinical Immunology - Tập 256 - Trang 109796 - 2023
Marta Dafne Cabanero-Navalon1,2, Victor Garcia-Bustos1,3, Alex Mira4, Pedro Moral Moral1,2, Miguel Salavert-Lleti3,5, María José Forner Giner6, María Núñez Beltrán1, José Todolí Parra1,2, Carme Bracke7, Miguel Carda-Diéguez4
1Primary Immune Deficiencies Unit, Department of Internal Medicine, University and Polytechnic Hospital La Fe, Valencia, Spain
2Research Group of Chronic Diseases and HIV Infection, Health Research Institute La Fe, Valencia, Spain
3Severe Infection Research Group, Health Research Institute La Fe, Valencia, Spain
4Genomics & Health Department, FISABIO Foundation, Valencia, Spain
5Unit of Infectious Diseases, Department of Internal Medicine of the University and Polytechnic Hospital La Fe, Valencia, Spain
6Department of Internal Medicine, University Clinical Hospital, Valencia, Spain
7Department of Infectious Diseases, Germans Trias i Pujol Hospital, Badalona, Spain

Tài liệu tham khảo

Picard, 2018, International union of immunological societies: 2017 primary immunodeficiency diseases committee report on inborn errors of immunity, J. Clin. Immunol., 38, 96, 10.1007/s10875-017-0464-9 Seidel, 2019, The European Society for Immunodeficiencies (ESID) registry working definitions for the clinical diagnosis of inborn errors of immunity, J Allergy Clin Immunol Pract, 7, 1763, 10.1016/j.jaip.2019.02.004 Ameratunga, 2020, Perspective: E evolving concepts in the diagnosis and understanding of common variable immunodeficiency disorders (CVID), Clin. Rev. Allergy Immunol., 59, 109, 10.1007/s12016-019-08765-6 Fischer, 2017, Autoimmune and inflammatory manifestations occur frequently in patients with primary immunodeficiencies, J. Allergy Clin. Immunol., 140, 1388, 10.1016/j.jaci.2016.12.978 Resnick, 2012, Morbidity and mortality in common variable immune deficiency over 4 decades, Blood, 119, 1650, 10.1182/blood-2011-09-377945 Orange, 2010, Impact of trough IgG on pneumonia incidence in primary immunodeficiency: a meta-analysis of clinical studies, Clin. Immunol., 137, 21, 10.1016/j.clim.2010.06.012 Chapel, 2012, Confirmation and improvement of criteria for clinical phenotyping in common variable immunodeficiency disorders in replicate cohorts, J. Allergy Clin. Immunol., 130, 1197, 10.1016/j.jaci.2012.05.046 Gereige, 2019, Current understanding and recent developments in common variable immunodeficiency associated autoimmunity, Front. Immunol., 10, 2753, 10.3389/fimmu.2019.02753 Jørgensen, 2019, Autoimmunity and inflammation in CVID: a possible crosstalk between immune activation, gut microbiota, and epigenetic modifications, J. Clin. Immunol., 39, 30, 10.1007/s10875-018-0574-z Berbers, 2017, Microbial dysbiosis in common variable immune deficiencies: evidence, causes, and consequences, Trends Immunol., 38, 206, 10.1016/j.it.2016.11.008 Perreau, 2014, Exhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders, J. Exp. Med., 211, 2033, 10.1084/jem.20140039 Jørgensen, 2016, Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation, Mucosal Immunol., 9, 1455, 10.1038/mi.2016.18 Ricci, 2021, The role of lung colonization in connective tissue disease-associated interstitial lung disease, Microorganisms., 9, 932, 10.3390/microorganisms9050932 Inaoka, 2019, Host-microbe interactions in the pathogenesis and clinical course of sarcoidosis, J. Biomed. Sci., 26, 45, 10.1186/s12929-019-0537-6 Young, 2016, The gut-liver-lung axis. Modulation of the innate immune response and its possible role in chronic obstructive pulmonary disease, Am. J. Respir. Cell Mol. Biol., 54, 161, 10.1165/rcmb.2015-0250PS Varricchi, 2021, Gut microbiome and common variable immunodeficiency: few certainties and many outstanding questions, Front. Immunol., 12, 10.3389/fimmu.2021.712915 Hand, 2016, The role of the microbiota in shaping infectious immunity, Trends Immunol., 37, 647, 10.1016/j.it.2016.08.007 Huang, 2018, S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense, Science., 359, 114, 10.1126/science.aam5809 Berbers, 2020, Low IgA associated with oropharyngeal microbiota changes and lung disease in primary antibody deficiency, Front. Immunol., 11, 1245, 10.3389/fimmu.2020.01245 Crescenzi, 2019, Liver stiffness assessment by transient elastography suggests high prevalence of liver involvement in common variable immunodeficiency, Dig. Liver Dis., 51, 1599, 10.1016/j.dld.2019.05.016 Rosier, 2020, Nitrate as a potential prebiotic for the oral microbiome, Sci. Rep., 10, 12895, 10.1038/s41598-020-69931-x Dzidic, 2018, Oral microbiome development during childhood: an ecological succession influenced by postnatal factors and associated with tooth decay, Isme J., 12, 2292, 10.1038/s41396-018-0204-z Callahan, 2016, DADA2: High-resolution sample inference from Illumina amplicon data, Nat. Methods, 13, 581, 10.1038/nmeth.3869 Quast, 2013, The SILVA ribosomal RNA gene database project: improved data processing and web-based tools, Nucleic Acids Res., 41 R Development Core Team, 2016, R: a language and environment for statistical computing, R. Found. Stat. Comput. Oksanen Lin, 2020, Analysis of compositions of microbiomes with bias correction, Nat. Commun., 11, 3514, 10.1038/s41467-020-17041-7 Havsed, 2021, Bacterial composition and metabolomics of dental plaque from adolescents, Front. Cell. Infect. Microbiol., 11, 10.3389/fcimb.2021.716493 Bosák, 2021, Patients with common variable immunodeficiency (CVID) show higher gut bacterial diversity and levels of low-abundance genes than the healthy housemates, Front. Immunol., 12, 10.3389/fimmu.2021.671239 Shulzhenko, 2018, CVID enteropathy is characterized by exceeding low mucosal IgA levels and interferon-driven inflammation possibly related to the presence of a pathobiont, Clin. Immunol., 197, 139, 10.1016/j.clim.2018.09.008 Fiedorová, 2019, Bacterial but not fungal gut microbiota alterations are associated with common variable immunodeficiency (CVID) phenotype, Front. Immunol., 10, 1914, 10.3389/fimmu.2019.01914 Macpherson, 2020, Gut microbiota-dependent trimethylamine N-oxide associates with inflammation in common variable immunodeficiency, Front. Immunol., 11, 10.3389/fimmu.2020.574500 van Schewick, 2020, Altered microbiota, impaired quality of life, malabsorption, infection, and inflammation in CVID patients with diarrhoea, Front. Immunol., 11, 1654, 10.3389/fimmu.2020.01654 Skarpengland, 2022, Altered plasma fatty acids associate with gut microbial composition in common variable immunodeficiency, J. Clin. Immunol., 42, 146, 10.1007/s10875-021-01146-9 Franco-Esquivias, 2019, Gut microbiota in Mexican patients with common variable immunodeficiency, Gac. Med. Mex., 155, 447 Park, 2021, Oral-gut microbiome axis in gastrointestinal disease and cancer, Cancers (Basel), 13, 2124, 10.3390/cancers13092124 Konig, 2020, The microbiome in autoimmune rheumatic disease, Best Pract. Res. Clin. Rheumatol., 34, 10.1016/j.berh.2019.101473 Camelo-Castillo, 2019, Nasopharyngeal microbiota in children with invasive pneumococcal disease: identification of bacteria with potential disease-promoting and protective effects, Front. Microbiol., 10, 11, 10.3389/fmicb.2019.00011 Atarashi, 2017, Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation, Science., 358, 359, 10.1126/science.aan4526 Arimatsu, 2014, Oral pathobiont induces systemic inflammation and metabolic changes associated with alteration of gut microbiota, Sci. Rep., 4, 4828, 10.1038/srep04828 Henares, 2021, Differential nasopharyngeal microbiota composition in children according to respiratory health status, Microb. Genom., 7 Cabrera-Rubio, 2012, Microbiome diversity in the bronchial tracts of patients with chronic obstructive pulmonary disease, J. Clin. Microbiol., 50, 3562, 10.1128/JCM.00767-12 Matson, 2021, B cell dysregulation in common variable immunodeficiency interstitial lung disease, Front. Immunol., 11, 10.3389/fimmu.2020.622114 Cabanero-Navalon, 2022, Integrating clinics, laboratory, and imaging for the diagnosis of common variable immunodeficiency-related granulomatous-lymphocytic interstitial lung disease, Front. Immunol., 13, 10.3389/fimmu.2022.813491 Gao, 2022, The oral microbiome and its role in systemic autoimmune diseases: a systematic review of big data analysis, Front Big Data, 5, 10.3389/fdata.2022.927520 Tan, 2002, Clinical characteristics of children with complicated pneumonia caused by Streptococcus pneumoniae, Pediatrics., 110, 1, 10.1542/peds.110.1.1 Becker, 2019, The composition of the pulmonary microbiota in sarcoidosis - an observational study, Respir. Res., 20, 46, 10.1186/s12931-019-1013-2 Moschen, 2016, Lipocalin 2 protects from inflammation and tumorigenesis associated with gut microbiota alterations, Cell Host Microbe, 19, 455, 10.1016/j.chom.2016.03.007 Parker, 2020, The genus alistipes: gut bacteria with emerging implications to inflammation, cancer, and mental health, Front. Immunol., 11, 906, 10.3389/fimmu.2020.00906 Poto, 2023, Correction to: is there a role for microbiome-based approach in common variable immunodeficiency?, Clin. Exp. Med. Cao, 2022, The gut virome: a new microbiome component in health and disease, EBioMedicine., 81, 10.1016/j.ebiom.2022.104113