Dyscirculatory Encephalopathy in Chernobyl Disaster Clean-Up Workers (a 20-year study)
Tóm tắt
Results obtained over 20-years of following 536 Chernobyl clean-up workers and 436 control subjects are presented. Dyscirculatory encephalopathy developed more frequently in persons exposed to radiation at age 30 years. As compared with the control group, workers were characterized by early onset of disease, faster progression, stable symptomatology for 5–6 years, and further progression of disease in the form of autonomic dysfunction, psycho-organic syndrome, and epilepsy. Major strokes were also more common in clean-up workers.
Tài liệu tham khảo
K. N. Badmaev and R. V. Smirnova, Radionuclide Diagnosis and Radiotherapy of Nervous System Diseases [in Russian], Moscow (1982).
V. A. Baraboi, “Radiobiology and the Chernobyl disaster,” Radiobiologiya, 30, No. 4, 435–440 (1990).
V. M. Borets and V. P. Gaponova, “Changes in metabolism in ischemic heart disease after the Chernobyl Nuclear Power Station accident,” Zdravookhr. Belorus., 12, 37–42 (1993).
L. A. Voitik, “Characteristics of the formation of cerebrovascular pathology in clean-up workers,” in: Medical Consequences of the Chernobyl Catastrophe: Proc. Sci.-Pract. Conf. (25th Anniversary of the Research and Clinical Institute of Radiation Medicine and Endocrinology Clinic), Minsk (1977), pp. 50–51.
A. K. Guskova and I. N. Shakirova, “Responses of the nervous system to harmful ionizing radiation,” Zh. Nevropatol. Psikhiat., 89, 138–141 (1989).
N. K. Denisevich, I. V. Malakhova, and S. M. Polyakov, “Invalidity due to diseases of the circulatory system in the population of Belarus suffering as a result of the Chernobyl Nuclear Power Station catastrophe,” Med.-Biol. Asp. Avar. CHAÉS, 2, 3–8 (2001).
M. P. Zakharash, B. V. Pshenichnikov, and N. V. Ivanova, “Radiation sclerosis and contemporary investigations,” in: Sanitation in Population Sites (Guidelines) [in Russian], Kiev (2000), pp. 86–93.
O. O. Kozozoeva, V. A. Rozanov, and T. I. Oleshko, “Assessment of the effects of small doses of ionizing radiation on CNS metabolism and function and correction of the biological response using GABAtropic agents,” Byull. Assots. Neirokhirug. Ukr., 6, 124–129 (1998).
N. G. Kruchinskii, “Long-term interactions of low doses of radiation: mechanisms of formation of hemostasis pathology,” Efferent. Ter., 9, No. 4, 15–26 (2003).
S. M. Kuznetsova, E. P. Krasilenko, and V. V. Kuznetsov, “Vascular brain diseases and the cerebral circulation in Chernobyl Nuclear Power Station accident clean-up workers,” Klin. Gerontol., 8, 18–28 (2004).
Yu. L. Kurako and A. P. Ivaniv, “Encephalopathy,” Mezhdun. Med. Zh., 4, 38–43 (1999).
V. I. Legeza, “Chernobyl Nuclear Power Station accident clean-up workers – 10 years on,” Ter. Arkh., 1, 77–79 (1998).
M. V. Merzlikina, T. V. Kryachkova, E. D. Zhelobetskaya, and A. G. Bespalov, “Characteristics of the brain hemodynamic response to mild physical exercise in Chernobyl Nuclear Power Station accident clean-up workers,” in: Proc. 3rd Siberian Congr. Ultrasound Diagnosis Physicians [in Russian],V. P. Kulikov (ed.) (2005), pp. 18.
Yu. A. Moskalev, Long-Term Sequelae of Exposure to Ionizing Radiation [in Russian], Meditsina, Moscow (1991).
S. Nemechek, Introduction to Neurobiology [in Russian], Prague (1978).
I. V. Podsonnaya and V. A. Golovin, “Blood flow changes in the carotid basin based on ultrasound angioscanning in Chernobyl Nuclear Power Station accident clean-up workers,” in: Proc. 3rd Siberian Congr. Ultrasound Diagnosis Physicians [in Russian], V. P. Kulikov (ed.) (2005), pp. 19.
I. V. Podsonnaya, G. G. Efremushkin, and V. A. Golovin, “Age-related characteristics of the state of hemostasis in Chernobyl Nuclear Power Station accident clean-up workers in the long-term period,” Klin. Gerontol., 11, No. 9, 62 (2005).
I. V. Podsonnaya, G. I. Shumakher, and T. V. Shamshina, “The state of cerebral hemodynamics in cerebrovascular diseases in Chernobyl Nuclear Power Station accident clean-up workers,” in: Proc. 1st Siberian and Far East Congr. Therapists [in Russian], (2005), pp. 571–572.
V. I. Taitslin, V. A. Cherevatenko, and V. A. Korinyak, “Diagnostic criteria for the adaptive capacities of the nervous system in Chernobyl catastrophe clean-up workers,” Byull. Assots. Neirokhirurg. Ukr., 6, 122 (1998).
O. V. Teplyakov, L. A. Sokolova, and T. O. Brodovskaya, “Ultrasound dopplerography of the cerebral arteries and brain in Chernobyl Nuclear Power Station accident clean-up workers in the long-term period, relationship between impairments and chronic pain syndrome,” Gosp. Vestn., 1, 9–13 (2007).
I. B. Ushakov, B. I. Davydov, and S. K. Soldatov, “Long-term sequelae of small doses of radiation,” Med. Truda Promyshl. Ekol., 1, 15–26 (2000).
N. N. Yakhno and I. V. Damulin, “Dyscirculatory (vascular) encephalopathy,” Ros. Med. Zh., 5, 41–43 (1999).