Dynamic coronary MR angiography and first‐pass perfusion with intracoronary administration of contrast agent

Journal of Magnetic Resonance Imaging - Tập 16 Số 3 - Trang 311-319 - 2002
Nikolaos V. Tsekos1, Pamela K. Woodard1, Glenn Foster2, Pavlos Moustakidis2, Terry L. Sharp2, Pilar Herrero1, Robert J. Gropler1
1Cardiovascular Imaging Laboratory, Mallinckrodt Institute of Radiology, Washington University Medical Center, St. Louis, Missouri
2Division of Radiological Sciences, Mallinckrodt Institute of Radiology, Washington University Medical Center, St Louis, Missouri

Tóm tắt

AbstractPurposeTo evaluate whether dynamic imaging of the coronary arteries can be performed with intracoronary infusion of low‐dose gadolinium (Gd)‐based contrast agent and assess the effect of long duration and multiple infusions on the image signal‐to‐noise ratio (SNR) and contrast‐to‐noise ratio (CNR).Materials and MethodsDynamic coronary magnetic resonance (MR) imaging (130 msec/image) and contrast agent first pass myocardial perfusion studies were performed with intracoronary infusions of low‐dose Gd‐based MR contrast agent on dogs (N = 4) using a fast multislice gradient recalled echo (GRE) sequence.ResultsContrast‐enhanced coronary arteries were clearly imaged during infusion periods as long as 2.3 minutes. The SNR and CNR of the contrast‐enhanced coronary arteries remained essentially unchanged over multiple consecutive angiographic sessions. In addition, we demonstrated that first pass studies performed with intracoronary injection of MR contrast agent can be used as a means of assessing regional myocardial perfusion.ConclusionThese studies demonstrated that, using intracoronary infusion of Gd, coronary magnetic resonance angiography (MRA) can be performed with high temporal resolution, and multiple low‐dose slow infusions of Gd‐based MR contrast agent can be performed without compromise of the vessel SNR and CNR. J. Magn. Reson. Imaging 2002;16:311–319. © 2002 Wiley‐Liss, Inc.

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Tài liệu tham khảo

10.1002/mrm.1910240215

10.1148/radiology.202.2.9015094

10.1148/radiology.208.2.9680574

10.1016/S1051-0443(07)61433-X

10.1148/radiology.215.2.r00ma34516

10.1148/radiology.204.2.9240516

10.1148/radiology.204.2.9240515

10.1148/radiology.202.1.8988223

10.1002/mrm.1910400304

10.1002/(SICI)1522-2586(199909)10:3<317::AID-JMRI14>3.0.CO;2-M

10.1002/(SICI)1522-2594(200005)43:5<645::AID-MRM5>3.0.CO;2-E

10.1002/mrm.1910290322

10.1002/jmri.1880080142

10.1002/mrm.1910370623

10.1097/00004424-199309001-00009

10.1097/00004424-199704000-00001

10.1016/S1051-0443(98)70429-4

SerfatyJM YangX KumarA AtalarE.Coronary artery intervention guided with magnetic resonance imaging. In: Proceedings of the 9th Annual Meeting of ISMRM Glasgow Scotland 2001. p541.

10.1161/hc0702.104165

Edelman RR, 1993, Magnetic resonance angiography and flow quantification of coronary arteries, Magn Reson Imaging Clin North Am, 1, 339, 10.1016/S1064-9689(21)00312-3

10.1097/00004424-199809000-00014

10.1002/mrm.1910360408

10.1002/mrm.1910370306

10.1148/radiology.217.1.r00se42290

10.1002/mrm.1910340408

10.1002/mrm.1910360209

10.1148/radiology.201.3.8939236

10.1118/1.595711

Woodard PK, 1999, Coronary MR angiography, Magn Reson Imaging Clin North Am, 7, 365, 10.1016/S1064-9689(21)00028-3

10.1002/(SICI)1522-2586(199911)10:5<676::AID-JMRI10>3.0.CO;2-L

10.1177/000331970005100309

10.1002/1522-2586(200010)12:4<590::AID-JMRI11>3.0.CO;2-3

GreenJ OmaryR VasireddyS et al.MR coronary artery imaging with intraarterial Gd injections with an inversion recovery prepared sequence in canines. In: 5th Annual Scientific Sessions of the Society for Cardiovascular MR. Lake Buena 2002. p31.

10.1002/1522-2594(200102)45:2<206::AID-MRM1028>3.0.CO;2-L

10.1002/mrm.10042

10.1002/mrm.1910350425

10.1002/jmri.1880080505

FrayneR GristTM SwanJS PetersDC KorosecFR MistreattaCA.Contrast agent injection protocols for 3D MR DSA: effects of injection order volume and rate. In: Proceedings of the 6th Annual Meeting of ISMRM Sydney Australia 1998. p770.

CarrollTJ KorosecFR SwanJS MistrettaCA.The effect of injection rate on contrast enhanced peripheral MRA. In: Proceedings of the 8th Annual Meeting of ISMRM Denver 2000. p1793.

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Journal of Magnetic Resonance Imaging

Tập 16 Số 3

311-319

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