Dust mite allergen avoidance as a preventive and therapeutic strategy

WHO: Asthma Scope and Burden. http://www.who.int/respiratory/asthma/scope/en/index.html. Accessed February 24, 2006. Martinez FD: Viruses and atopic sensitization in the first years of life. Am J Respir Crit Care Med 2000, 162:S95-S99. Alm JS, Swartz J, Lilja G, et al.: Atopy in children of families with an anthroposophic lifestyle. Lancet 1999, 353:1485–1488. Bjorksten B, Naaber P, Sepp E et al.: The intestinal microfiora in allergic Estonian and Swedish 2-year-old children. Clin Exp Allergy 1999, 29:342–346. Simpson BM, Custovic A, Simpson A, et al.: NAC Manchester Asthma and Allergy Study (NACMAAS): risk factors for asthma and allergic disorders in adults. Clin Exp Allergy 2001, 31:391–399. Custovic A, Hallam CL, Simpson BM, et al.: Decreased prevalence of sensitization to cats with high exposure to cat allergen. J Allergy Clin Immunol 2001, 108:537–539. Braun-Fahrlander C, Riedler J, Herz U, et al.: Environmental exposure to endotoxin and its relation to asthma in school-age children. N Engl J Med 2002, 347:869–877. Squillace SP, Sporik RB, Rakes G, et al.: Sensitization to dust mites as a dominant risk factor for asthma among adolescents living in central Virginia. Multiple regression analysis of a population-based study. Am J Respir Crit Care Med 1997, 156:1760–1764. Pollart SM, Chapman MD, Fiocco GP, et al.: Epidemiology of acute asthma: IgE antibodies to common inhalant allergens as a risk factor for emergency room visits. J Allergy Clin Immunol 1989, 83:875–882. Nelson RP Jr, Di Nicolo R, Fernandez-Caldas E, et al.: Allergen-specific IgE levels and mite allergen exposure in children with acute asthma first seen in an emergency department and in nonasthmatic control subjects. J Allergy Clin Immunol 1996, 98:258–263. van Strien RT, Verhoeff AP, van Wijnen JH, et al.: Infant respiratory symptoms in relation to mite allergen exposure. Eur Respir J 1996, 9:926–931. Tan BB, Weald D, Strickland I, et al.: Double-blind controlled trial of effect of housedust-mite allergen avoidance on atopic dermatitis. Lancet 1996, 347:15–18. Custovic A, Taggart SC, Francis HC, et al.: Exposure to house dust mite allergens and the clinical activity of asthma. J Allergy Clin Immunol 1996, 98:64–72. Platts-Mills TA, Thomas WR, Aalberse RC, et al.: Dust mite allergens and asthma: report of a second international workshop. J Allergy Clin Immunol 1992, 89:1046–1060. Gore RB, Durrell B, Bishop S, et al.: High-efficiency vacuum cleaners increase personal mite allergen exposure, but only slightly. Allergy 2006, 61:119–123. Kroidl RF, Gobel D, Balzer D, et al.: Clinical effects of benzyl benzoate in the prevention of house-dust-mite allergy. Results of a prospective, double-blind, multicenter study. Allergy 1998, 53:435–440. Simpson A, Simpson B, Custovic A, et al.: Stringent environmental control in pregnancy and early life: the longterm effects on mite, cat and dog allergen. Clin Exp Allergy 2003, 33:1183–1189. Hide DW, Matthews S, Matthews L, et al.: Effect of allergen avoidance in infancy on allergic manifestations at age two years. J Allergy Clin Immunol 1994, 93:842–846. Hide DW, Matthews S, Tariq S, et al.: Allergen avoidance in infancy and allergy at 4 years of age. Allergy 1996, 51:89–93. Arshad SH, Matthews S, Gant C, et al.: Effect of allergen avoidance on development of allergic disorders in infancy. Lancet 1992, 339:1493–1497. Arshad SH, Bateman B, Matthews SM: Primary prevention of asthma and atopy during childhood by allergen avoidance in infancy: a randomised controlled study. Thorax 2003, 58:489–493. Isle of Wight study showing benefits of primary prevention at age 8 years. Becker A, Watson W, Ferguson A, et al.: The Canadian asthma primary prevention study: outcomes at 2 years of age. J Allergy Clin Immunol 2004, 113:650–656. Chan-Yeung M, Ferguson A, Watson W, et al.: The Canadian Childhood Asthma Primary Prevention Study: outcomes at 7 years of age. J Allergy Clin Immunol 2005, 116:49–55. Canadian study showing benefits of primary prevention at age 7 years. Halmerbauer G, Gartner C, Schierl M, et al.: Study on the Prevention of Allergy in Children in Europe (SPACE): allergic sensitization at 1 year of age in a controlled trial of allergen avoidance from birth. Pediatr Allergy Immunol 2003, 14:10–17. Horak F Jr, Matthews S, Ihorst G, et al.: Effect of miteimpermeable mattress encasings and an educational package on the development of allergies in a multinational randomized, controlled birth-cohort study—24 months results of the Study of Prevention of Allergy in Children in Europe. Clin Exp Allergy 2004, 34:1220–1225. SPACE study—European primary prevention study showed differences regarding sensitization in first year but failed to detect differences in allergic symptoms at age 2 years. Brunekreef B, van Strien R, Pronk A, et al.: La mano de DIOS. Was the PIAMA intervention study intervened upon? Allergy 2005, 60:1083–1086. Koopman LP, van Strien RT, Kerkhof M, et al.: Placebocontrolled trial of house dust mite-impermeable mattress covers: effect on symptoms in early childhood. Am J Respir Crit Care Med 2002, 166:307–313. Mihrshahi S, Peat JK, Marks GB, et al.: Eighteen-month outcomes of house dust mite avoidance and dietary fatty acid modification in the Childhood Asthma Prevention Study (CAPS). J Allergy Clin Immunol 2003, 111:162–168. Peat JK, Mihrshahi S, Kemp AS, et al.: Three-year outcomes of dietary fatty acid modification and house dust mite reduction in the Childhood Asthma Prevention Study. J Allergy Clin Immunol 2004, 114:807–813. Australian study showing benefits of mite avoidance and dietary intervention on wheeze at age 18 months—decreased sensitization among intervention group at age 3 years. Custovic A, Simpson BM, Murray CS, et al.: The National Asthma Campaign Manchester Asthma and Allergy Study. Pediatr Allergy Immunol 2002, 13(Suppl 15):32–37. Custovic A, Simpson BM, Simpson A, et al.: Manchester Asthma and Allergy Study: low-allergen environment can be achieved and maintained during pregnancy and in early life. J Allergy Clin Immunol 2000, 105:252–258. Custovic A, Simpson BM, Simpson A, et al.: Effect of environmental manipulation in pregnancy and early life on respiratory symptoms and atopy during first year of life: a randomised trial. Lancet 2001, 358:188–193. Woodcock A, Lowe LA, Murray CS, et al.: Early life environmental control: effect on symptoms, sensitization, and lung function at age 3 years. Am J Respir Crit Care Med 2004, 170:433–439. MAAS study, a primary prevention study showing benefit on lung functions in mite sensitized 3 year old children. Cloosterman SG, Schermer TR, Bijl-Hofland ID, et al.: Effects of house dust mite avoidance measures on Der p 1 concentrations and clinical condition of mild adult house dust mite-allergic asthmatic patients, using no inhaled steroids. Clin Exp Allergy 1999, 29:1336–1346. Woodcock A, Forster L, Matthews E, et al.: Control of exposure to mite allergen and allergen-impermeable bed covers for adults with asthma. N Engl J Med 2003, 349:225–236. The largest double-blind, placebo controlled secondary prevention study in asthmatic adults showing no benefit on clinical outcomes. Luczynska C, Tredwell E, Smeeton N, Burney P: A randomized controlled trial of mite allergen-impermeable bed covers in adult mite-sensitized asthmatics. Clin Exp Allergy 2003, 33:1648–1653. Secondary prevention study in adult asthmatics failed to demonstrate a beneficial effect of mite avoidance on clinical symptoms. van den Bemt L, van Knapen L, de Vries MP, et al.: Clinical effectiveness of a mite allergen-impermeable bed-covering system in asthmatic mite-sensitive patients. J Allergy Clin Immunol 2004, 114:858–862. Gotzsche PC, Johansen HK, Schmidt LM, et al.: House dust mite control measures for asthma. Cochrane Database Syst Rev 2004, 4:CD001187. Recent Cochrane analysis on secondary prevention. Gotzsche PC, Johansen HK, Burr ML, Hammarquist C: House dust mite control measures for asthma. Cochrane Database Syst Rev 2001, 3:CD001187. Halken S, Host A, Niklassen U, et al.: Effect of mattress and pillow encasings on children with asthma and house dust mite allergy. J Allergy Clin Immunol 2003, 111:169–176. Morgan WJ, Crain EF, Gruchalla RS, et al.: Results of a home-based environmental intervention among urban children with asthma. N Engl J Med 2004, 351:1068–1080. A large, multifaceted intervention study in children from lowersocioeconomic group showing benefit of environmental interventionon clinical disease. Carswell F, Birmingham K, Oliver J, et al.: The respiratory effects of reduction of mite allergen in the bedrooms of asthmatic children—a double-blind controlled trial. Clin Exp Allergy 1996, 26:386–396. Wood RA, Chapman MD, Adkinson NF, et al.: The effect of cat removal on allergen content in household-dust samples. J Allergy Clin Immunol 1989, 83:730–734. Custovic A, Green R, Taggart SC, et al.: Domestic allergens in public places. II: Dog (Can f1) and cockroach (Bla g 2) allergens in dust and mite, cat, dog and cockroach allergens in the air in public buildings. Clin Exp Allergy 1996, 26:1246–1252. Wood RA, Johnson EF, Van Natta ML, et al.: A placebocontrolled trial of a HEPA air cleaner in the treatment of cat allergy. Am J Respir Crit Care Med 1998, 158:115–120. van der Heide S, van Aalderen WM, Kauffman HF, et al.: Clinical effects of air cleaners in homes of asthmatic children sensitized to pet allergens. J Allergy Clin Immunol 1999, 104:447–451. Francis H, Fletcher G, Anthony C, et al.: Clinical effects of air filters in homes of asthmatic adults sensitized and exposed to pet allergens. Clin Exp Allergy 2003, 33:101–105.