Dual effect of serotonin on formalin-induced nociception in the rat spinal cord

Alhaider, 1991, Spinal 5-HT3 receptor-mediated antinociception: possible release of GABA, J. Neurosci., 11, 1881, 10.1523/JNEUROSCI.11-07-01881.1991

Boess, 1994, Molecular biology of 5-HT receptors, Neuropharmacology, 33, 275, 10.1016/0028-3908(94)90059-0

Daval, 1987, Autoradiographic evidence of serotonin1 binding sites on primary afferent fibers in the dorsal horn of the rat spinal cord, Neurosci. Lett., 83, 71, 10.1016/0304-3940(87)90218-7

Del Mal, 1994, Serotonin inhibits high-threshold Ca2+ channel currents in capsaicin-sensitive acutely isolated adult rat DRG neurons, J. Neurophysiol., 72, 2551, 10.1152/jn.1994.72.5.2551

Derkach, 1989, 5-HT3 receptors are membrane ion channels, Nature, 339, 706, 10.1038/339706a0

Dubuisson, 1977, The formalin test: a quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats, Pain, 4, 161, 10.1016/0304-3959(77)90130-0

Eide, 1988, Increased behavioral response to intrathecal serotonin after lesion of serotonergic pathways with 5,7-dihydroxytryptamine seems not to be due to depletion of serotonin, Acta Physiol. Scand., 134, 291, 10.1111/j.1748-1716.1988.tb08491.x

Fasmer, 1983, Similar behavioural effects of 5-hydroxytryptamine and substance P injected intrathecally in mice, Neuropharmacology, 22, 485, 10.1016/0028-3908(83)90167-3

Fasmer, 1985, Changes in nociception after lesions of descending serotonergic pathways induced with 5,6-dihydroxytryptamine. Different effects in the formalin and tail-flick tests, Neuropharmacology, 24, 729, 10.1016/0028-3908(85)90006-1

Fasmer, 1986, Changes in nociception after 6-hydroxydopamine lesions of descending catecholaminergic pathways in mice, Pharmacol. Biochem. Behav., 24, 1441, 10.1016/0091-3057(86)90207-8

Glaum, 1988, Reversal of the antinociceptive effects of intrathecally administered serotonin in the rat by a selective 5-HT3 receptor antagonist, Neurosci. Lett., 95, 313, 10.1016/0304-3940(88)90677-5

Glaum, 1990, 5-HT3 receptors modulate spinal nociceptive reflexes, Brain Res., 510, 12, 10.1016/0006-8993(90)90721-M

Hammond, 1985, Efflux of 5-hydroxytryptamine and noradrenaline into spinal cord superfusates during stimulation of the rat medulla, J. Physiol., 359, 151, 10.1113/jphysiol.1985.sp015579

Hamon, 1989, 5-HT3 receptor binding sites are on capsaicin-sensitive fibers in the rat spinal cord, Eur. J. Pharmacol., 164, 315, 10.1016/0014-2999(89)90472-X

Hylden, 1983, Intrathecal serotonin in mice: analgesia and inhibition of a spinal action of substance P, Life Sci., 33, 789, 10.1016/0024-3205(83)90785-3

Kidd, 1993, 5-HT3 receptors in the rat central nervous system are mainly located on nerve fibres and terminals, Brain Res., 612, 289, 10.1016/0006-8993(93)91674-H

Maricq, 1991, Primary structure and functional expression of the 5-HT3 receptor, a serotonin-gated ion channel, Science, 254, 432, 10.1126/science.1718042

Millan, 1989, Apparent hyperalgesic action of the 5-HT1A agonist, 8-OH-DPAT, in the rat reflects induction of spontaneous tail-flicks, Neurosci. Lett., 107, 227, 10.1016/0304-3940(89)90822-7

Mjellem, 1992, The role of 5-HT1A and 5-HT1B receptors in spinal nociceptive transmission and in the modulation of NMDA induced behavior, Neuroreport, 3, 1061, 10.1097/00001756-199212000-00007

Mjellem, 1993, Different functions of spinal 5-HT1A and 5-HT2 receptor subtypes in modulating behavior induced by excitatory amino acid receptor agonists in mice, Brain Res., 626, 78, 10.1016/0006-8993(93)90565-5

Murphy, 1990, Selective serotonin1A/1B agonists differentially affect spinal nociceptive reflexes, Neuropharmacology, 29, 463, 10.1016/0028-3908(90)90168-Q

Pompeiano, 1992, Distribution and cellular localization of mRNA coding for 5-HT1A receptor in the rat brain: correlation with receptor binding, J. Neurosci., 12, 440, 10.1523/JNEUROSCI.12-02-00440.1992

Puig, 1992, Effect of subcutaneous administration of the chemical algogen formalin, on 5-HT metabolism in the nucleus raphe magnus and the medullary dorsal horn: a voltammetric study in freely moving rats, Brain Res., 590, 250, 10.1016/0006-8993(92)91102-K

Rivot, 1982, Increase of serotonin metabolism within the dorsal horn of the spinal cord during nucleus raphe magnus stimulation, as revealed by in vivo electrochemical detection, Brain Res., 238, 117, 10.1016/0006-8993(82)90775-2

Saria, 1990, 5-HT3 receptor antagonists inhibit sensory neuropeptide release from the rat spinal cord, Neuroreport, 1, 104, 10.1097/00001756-199010000-00005

Satoh, 1983, Bestatin potentiates analgesic effect of intrathecally administered dynorphin in rats, IRCS Med. Sci., 11, 965

Schmauss, 1983, Pharmacological antagonism of the antinociceptive effects of serotonin in the rat spinal cord, Eur. J. Pharmacol., 90, 349, 10.1016/0014-2999(83)90556-3

Shibata, 1989, Modified formalin test: characteristic biphasic pain response, Pain, 38, 347, 10.1016/0304-3959(89)90222-4

Solomon, 1988, Mechanisms of effects of intrathecal serotonin on nociception and blood pressure in rats, J. Pharmacol. Exp. Ther., 245, 905

Sugimoto, 1986, Involvement of medullary opioid-peptidergic and spinal noradrenergic systems in the regulation of formalin-induced persistent pain, Neuropharmacology, 25, 481, 10.1016/0028-3908(86)90171-1

Tecott, 1993, Nervous system distribution of the serotonin 5-HT3 receptor mRNA, 90, 1430

Thor, 1993, Autoradiographic localization of 5-hydroxytryptamine1A, 5-hydroxytryptamine1B and 5-hydroxytryptamine1C/2 binding sites in the rat spinal cord, Neuroscience, 55, 235, 10.1016/0306-4522(93)90469-V

Tjølsen, 1991, Antinociceptive effect of paracetamol in rats is partly dependent on the spinal serotonergic systems, Eur. J. Pharmacol., 193, 193, 10.1016/0014-2999(91)90036-P

Todorovic, 1990, Pharmacological characterization of 5-hydroxytryptamine2 and 5-hydroxytryptamine3 receptors in rat dorsal root ganglion cells, J. Pharmacol. Exp. Ther., 254, 109

Todorovic, 1992, Serotonin preferentially hyperpolarizes capsaicin-sensitive C type sensory neurons by activating 5-HT1A receptors, Brain Res., 585, 212, 10.1016/0006-8993(92)91209-W

Wilcox, 1992, Role of 5-HT3 receptors in pain modulation in the spinal cord, 275

Yaksh, 1979, Spinal serotonin terminal system mediates antinociception, J. Pharmacol. Exp. Ther., 208, 446

Zemlan, 1994, 5-HT1A receptors mediate the effect of the bulbospinal serotonin system on spinal dorsal horn nociceptive neurons, Pharmacology, 48, 1, 10.1159/000139156

Zimmermann, 1983, Ethical guidelines for investigations of experimental pain in conscious animals [editorial], Pain, 16, 109, 10.1016/0304-3959(83)90201-4