Drug-like properties and the causes of poor solubility and poor permeability

Journal of Pharmacological and Toxicological Methods - Tập 44 Số 1 - Trang 235-249 - 2000
Christopher A. Lipinski1
1Exploratory Medicinal Sciences, Pfizer Global Research and Development, Groton Laboratories, Eastern Point Road, Groton, CT 06340, USA

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