Drug Therapy in the Geriatric Animal

Bichet, 1982, Renal function and diseases in the aged, 211 Castelden, 1977, The effect of ageing on drug absorption from the gut, Age Ageing, 6, 138, 10.1093/ageing/6.3.138 Frazier, 1986, Increased gentamicin nephrotoxicity in normal and diseased dogs administered identical serum drug concentration profiles: Increased sensitivity in subclinical renal dysfunction, J Pharmacol Exp Ther, 239, 946 Gerber, 1982, Drug usage in the elderly, 51 Haass, 1972, Absorption rates of some cardiac glycosides and portal blood flow, Eur J Pharmacol, 19, 366, 10.1016/0014-2999(72)90103-3 Kaufman, 1984, Renal function in the geriatric dog, Compend Contin Ed Pract Vet, 6, 1087 Klotz, 1975, The effects of age and liver disease on the disposition and elimination of diazapam in adult man, J Clin Invest, 55, 347, 10.1172/JCI107938 Novak, 1972, Ageing, total body potassium, fat free mass and cell mass in males and females aged 18 and 85 years, J Gerontol, 27, 438, 10.1093/geronj/27.4.438 Peddinghaus, 1977, Spontaneous glomerulonephritis in dogs, Vet Pathol, 14, 121, 10.1177/030098587701400204 Riviere, 1984, Pharmacokinetics and comparative nephrotoxicity of fixed-dose versus fixed interval reduction of gentamicin dosage in subtotal nephrectomized dogs, Toxicol Appl Pharmacol, 75, 496, 10.1016/0041-008X(84)90186-8 Triggs, 1975, Pharmacokinetics in the elderly, Eur J Clin Pharmacol, 8, 55, 10.1007/BF00616415 Woodhouse, 1984, The effect of age on pathways of drug metabolism in human liver, Age Ageing, 13, 328, 10.1093/ageing/13.6.328 Woodhouse, 1984, The effect of alcoholic cirrhosis on the two kinetic compounds (high and low affinity) of the microsomal O-deethylation of 7-ethoxycoumarin in human liver, Eur J Clin Pharmacol, 26, 61, 10.1007/BF00546710