Doxorubicin-induced alterations in kidney functioning, oxidative stress, DNA damage, and renal tissue morphology; Improvement by Acacia hydaspica tannin-rich ethyl acetate fraction

Abdel Moneim, A.E., Othman, M.S., Aref, A.M., 2014. Azadirachta indica Attenuates Cisplatin-Induced Nephrotoxicity and Oxidative Stress. BioMed Res. Int., 2014.

Abdelmeguid, 2010, Protective effect of silymarin on cisplatin-induced nephrotoxicity in rats, Pak. J. Nutr., 9, 624, 10.3923/pjn.2010.624.636

Afsar, 2015, Antipyretic, anti-inflammatory and analgesic activity of Acacia hydaspica R. Parker and its phytochemical analysis, BMC Complement Altern. Med., 15, 136, 10.1186/s12906-015-0658-8

Afsar, 2017, Modulatory influence of Acacia hydaspica R. Parker ethyl acetate extract against cisplatin inveigled hepatic injury and dyslipidemia in rats, BMC Complement Altern. Med., 17, 307, 10.1186/s12906-017-1824-y

Afsar, 2017, Acacia hydaspica ethyl acetate extract protects against cisplatin-induced DNA damage, oxidative stress and testicular injuries in adult male rats, BMC Cancer, 17, 883, 10.1186/s12885-017-3898-9

Afsar, T., Razak, S., Almajwal, A., Shabbir, M., Khan, M. R. J. B. C. & Medicine, A., 2019. Evaluating the protective potency of Acacia hydaspica R. Parker on histological and biochemical changes induced by Cisplatin in the cardiac tissue of rats. 19, 182.

Afsar, 2017, Acacia hydaspica R. Parker prevents doxorubicin-induced cardiac injury by attenuation of oxidative stress and structural Cardiomyocyte alterations in rats, BMC Complement Altern. Med., 17, 554, 10.1186/s12906-017-2061-0

Afsar, 2017, Anti-depressant and anxiolytic potential of Acacia hydaspica R. Parker aerial parts extract: Modulation of brain antioxidant enzyme status, BMC Complement Altern. Med., 17, 228, 10.1186/s12906-017-1671-x

Afsar, 2016, Evaluation of antioxidant, anti-hemolytic and anticancer activity of various solvent extracts of Acacia hydaspica R. Parker aerial parts, BMC Complement Altern. Med., 16, 258, 10.1186/s12906-016-1240-8

Afsar, 2018, Antioxidant activity of polyphenolic compounds isolated from ethyl-acetate fraction of Acacia hydaspica R. Parker, Chem. Central J., 12, 5, 10.1186/s13065-018-0373-x

Afsar, 2016, Growth inhibition and apoptosis in cancer cells induced by polyphenolic compounds of Acacia Hydaspica: involvement of multiple signal transduction pathways, Sci. Rep., 6, 23077, 10.1038/srep23077

Ahmed, 2019, Protective effect of Silymarin against kidney injury induced by carbon tetrachloride in male rats, Iraqi J. Veter. Sci., 33, 127, 10.33899/ijvs.2019.125529.1051

Ahn, 2014, Protective effects of green tea polyphenol against cisplatin-induced nephrotoxicity in rats, Obstetr. Gynecol. Sci., 57, 464, 10.5468/ogs.2014.57.6.464

Ateşşahín, 2007, Role of Ellagic Acid against Cisplatin-Induced Nephrotoxicity and Oxidative Stress in Rats, Basic Clin. Pharmacol. Toxicol., 100, 121, 10.1111/j.1742-7843.2006.00015.x

Ayla, S., Seckin, I., Tanriverdi, G., Cengiz, M., Eser, M., Soner, B., Oktem, G., 2011. Doxorubicin induced nephrotoxicity: protective effect of nicotinamide. Int. J. Cell Biol..

Bao, 2016, The Green Tea Polyphenol (—)-epigallocatechin-3-gallate and its beneficial roles in chronic kidney disease, J. Trans. Int. Med., 4, 99, 10.1515/jtim-2016-0031

Benson, 1980, Increase of NAD (P) H: quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity, Proc. Natl. Acad. Sci., 77, 5216, 10.1073/pnas.77.9.5216

Carlberg, 1975, Purification and characterization of the flavoenzyme glutathione reductase from rat liver, J. Biol. Chem., 250, 5475, 10.1016/S0021-9258(19)41206-4

Carvalho, 2009, Doxorubicin: the good, the bad and the ugly effect, Curr. Med. Chem., 16, 3267, 10.2174/092986709788803312

Chakrabarty, 1996, The genus Acacia P. Miller (Leguminosae: Mimosoideae) in India, J. Econ. Taxonomic Botany, 20, 599

Dhondup, 2017, Electrolyte and acid-base disorders in chronic kidney disease and end-stage kidney failure, Blood Purificat., 43, 179, 10.1159/000452725

El-Sheikh, 2012, Effect of coenzyme-Q10 on doxorubicin-induced nephrotoxicity in rats, Adv. Pharm. Sci., 10.1155/2012/981461

Ghibu, 2012, General oxidative stress during doxorubicin-induced cardiotoxicity in rats: absence of cardioprotection and low antioxidant efficiency of alpha-lipoic acid, Biochimie, 94, 932, 10.1016/j.biochi.2011.02.015

Granados-Principal, 2010, New advances in molecular mechanisms and the prevention of adriamycin toxicity by antioxidant nutrients, Food Chem. Toxicol., 48, 1425, 10.1016/j.fct.2010.04.007

Grant, 2019, Sexual dimorphism of acute doxorubicin-induced nephrotoxicity in C57Bl/6 mice, PloS One, 14, e0212486, 10.1371/journal.pone.0212486

Green, 1982, Analysis of nitrate, nitrite, and [15 N] nitrate in biological fluids, Anal. Biochem., 126, 131, 10.1016/0003-2697(82)90118-X

Habig, 1974, Glutathione S-transferases the first enzymatic step in mercapturic acid formation, J. Biol. Chem., 249, 7130, 10.1016/S0021-9258(19)42083-8

Hsieh, 2004, Protective effect of methyl gallate from Toona sinensis (Meliaceae) against hydrogen peroxide-induced oxidative stress and DNA damage in MDCK cells, Food Chem. Toxicol., 42, 843, 10.1016/j.fct.2004.01.008

Iqbal, 2005, Antioxidant properties and components of some commercially available varieties of rice bran in Pakistan, Food Chem., 93, 265, 10.1016/j.foodchem.2004.09.024

Jabeen, 2009, Indigenous uses of economically important flora of Margallah hills national park, Islamabad, Pakistan, African J. Biotechnol., 8

Jalali, 2013, Crataegus monogyna fruit aqueous extract as a protective agent against doxorubicin-induced reproductive toxicity in male rats, Avicenna J. Phytomed., 3, 159

Jollow, 1974, Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3, 4-bromobenzene oxide as the hepatotoxic metabolite, Pharmacology, 11, 151, 10.1159/000136485

Kakkar, 1984, A modified spectrophotometric assay of superoxide dismutase, Indian J. Biochem. Biophys., 21, 130

Kanlaya, 2019, Protective effects of epigallocatechin-3-gallate from green tea in various kidney diseases, Adv. Nutrit., 10, 112, 10.1093/advances/nmy077

Khan, 2012, Protective effects of rutin against potassium bromate induced nephrotoxicity in rats, BMC Complement. Alternative Med., 12, 204, 10.1186/1472-6882-12-204

Khan, 2009, Studies on the protective effect of green tea against cisplatin induced nephrotoxicity, Pharmacol. Res., 60, 382, 10.1016/j.phrs.2009.07.007

Koriem, 2009, Role of some Egyptian medicinal plants against liver and kidney toxicity induced by cadmium chloride, Toxicol. Mech. Methods, 19, 524, 10.1080/15376510903121145

Lee, 2011, Adriamycin nephropathy: a model of focal segmental glomerulosclerosis, Nephrology, 16, 30, 10.1111/j.1440-1797.2010.01383.x

Lowry, 1951, Protein measurement with the Folin phenol reagent, J. Biol. Chem., 193, 265, 10.1016/S0021-9258(19)52451-6

Mizutani, 2005, Mechanism of apoptosis induced by doxorubicin through the generation of hydrogen peroxide, Life Sci., 76, 1439, 10.1016/j.lfs.2004.05.040

Mohammed, E.E., 2015. Nephro-protective Effect of Acacia senegal and Hyphaene thebacia Against Drug-induced Renal Damage in Rats. University of Khartoum.

Mohandas, 1984, Differential distribution of glutathione and glutathione-related enzymes in rabbit kidney: possible implications in analgesic nephropathy, Biochem. Pharmacol., 33, 1801, 10.1016/0006-2952(84)90353-8

Murakami, 2002, Effect of tea catechins on cellular lipid peroxidation and cytotoxicity in HepG2 cells, Biosci. Biotechnol. Biochem., 66, 1559, 10.1271/bbb.66.1559

Naqshbandi, 2012, Studies on the protective effect of dietary fish oil on cisplatin induced nephrotoxicity in rats, Food Chem. Toxicol., 50, 265, 10.1016/j.fct.2011.10.039

Nasr, 2014, Aged garlic extract protects against oxidative stress and renal changes in cisplatin-treated adult male rats, Cancer Cell In., 14, 92, 10.1186/s12935-014-0092-x

Naziroğlu, M., Karaoğlu, A., Aksoy, A.O., 2004. Selenium and high dose vitamin E administration protects cisplatin-induced oxidative damage to renal, liver and lens tissues in rats. Toxicology, 195, 221-230.

Nijveldt, 2001, Flavonoids: a review of probable mechanisms of action and potential applications, Am. J. Clin. Nutrit., 74, 418, 10.1093/ajcn/74.4.418

Nouri, 2019, Nephroprotective effect of silymarin against diclofenacinduced renal damage and oxidative stress in male rats, J. Herbmed Pharmacol., 10.15171/jhp.2019.23

Oda, 2012, Protective effect of silymarin on mercury-induced acute nephro-hepatotoxicity in rats, Studies, 35, 36

Orlowski, 1974, γ-Glutamyl transpeptidase in brain capillaries: possible site of a blood-brain barrier for amino acids, Science, 184, 66, 10.1126/science.184.4132.66

Pick, 1981, Rapid microassays for the measurement of superoxide and hydrogen peroxide production by macrophages in culture using an automatic enzyme immunoassay reader, J. Immunol. Methods, 46, 211, 10.1016/0022-1759(81)90138-1

Puga, 2015, Antioxidant activity and protection against oxidative-induced damage of Acacia shaffneri and Acacia farnesiana pods extracts: in vitro and in vivo assays, BMC Complement Altern. Med., 15, 435, 10.1186/s12906-015-0959-y

Rahman, 2006, Regulation of inflammation and redox signaling by dietary polyphenols, Biochem. Pharmacol., 72, 1439, 10.1016/j.bcp.2006.07.004

Ruggiero, 2017, Renal toxicity and chemotherapy in children with cancer, Brit. J. Clin. Pharmacol., 83, 2605, 10.1111/bcp.13388

Saad, 2009, Cisplatin induced damage in kidney genomic DNA and nephrotoxicity in male rats: the protective effect of grape seed proanthocyanidin extract, Food Chem. Toxicol., 47, 1499, 10.1016/j.fct.2009.03.043

Sakr, 2011, Protective effect of ginger (Zingiber officinale) on adriamycin-induced hepatotoxicity in albino rats, J. Med. Plant Res., 5, 133

Shahbazi, 2012, Potential renoprotective effects of silymarin against nephrotoxic drugs: a review of literature, J. Pharm. Pharm. Sci., 15, 112, 10.18433/J3F88S

Su, 2015, Protective effects of madecassoside against Doxorubicin induced nephrotoxicity in vivo and in vitro, Sci. Rep., 5, 18314, 10.1038/srep18314

Tatlidede, 2009, Resveratrol treatment protects against doxorubicin-induced cardiotoxicity by alleviating oxidative damage, Free Radical Res., 43, 195, 10.1080/10715760802673008

van Acker, 2000, 7-monohydroxyethylrutoside protects against chronic doxorubicin-induced cardiotoxicity when administered only once per week, Clin. Cancer Res., 6, 1337

Wang, 2016, Protective effects of green tea polyphenol against renal injury through ROS-mediated JNK-MAPK pathway in lead exposed rats, Mol. Cells., 39, 508, 10.14348/molcells.2016.2170

Wapstra, 1999, Dose of doxorubicin determines severity of renal damage and responsiveness to ACE-inhibition in experimental nephrosis, J. Pharmacol. Toxicol. Methods, 41, 69, 10.1016/S1056-8719(99)00015-5

Zhao, 2012, Protective effects of berberine on doxorubicin-induced hepatotoxicity in mice, Biol. Pharm. Bull., 35, 796, 10.1248/bpb.35.796