Mirjana Krotin1, Marija Zdravković1, Danica Popovic-Lisulov2, J. Saric2, Dušica Čeleketić1, Mirna Zaja2, Darko Zdravković1
1University of Belgrade
2Department of Cardiology, University Clinical Hospital Center Bezanijska Kosa, 11000, Belgrade, Serbia
Tóm tắt
Abstract
Multiple arterial and venous thromboses are usually related to thrombophilia or antiphospholipid syndrome. Recurrent pulmonary embolism strongly indicates the presence of genetic or acquired thrombophilic factors. Simultaneous double arterial in situ thromboses are unusual, even in thrombophilic conditions. Simultaneous occurrence of pulmonary embolism and cerebrovascular ischaemic insult are highly indicative of existence of patent foramen ovale. We present herein a patient with the double simultaneous arterial thromboses as the manifestation of thrombophilia (heterozygous for methylenetetrahydrofolate-reductase (MTHFR) C677T gene mutation). There was no patent foramen ovale suspected upon the patient’s admittance to hospital. To the best of our knowledge there have been no similar cases presented to date.
