Dosimetric Anchoring of In Vivo and In Vitro Studies for Perfluorooctanoate and Perfluorooctanesulfonate

Toxicological Sciences - Tập 136 Số 2 - Trang 308-327 - 2013
John F. Wambaugh1, R. Woodrow Setzer1, Ann M. Pitruzzello2, Jie Liu1, David M. Reif1, Nicole Kleinstreuer1, Nina Ching Y. Wang3, Nisha S. Sipes1, Matthew T. Martin1, Kaberi Das4, Jamie C. DeWitt5, Mark J. Strynar6, Richard Judson1, Keith A. Houck1, Christopher Lau4
1§National Center for Computational Toxicology, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711;
2Research Triangle Institute, Research Triangle Park, North Carolina 27711;
3National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Cincinnati, Ohio 45268;
4§National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711;
5Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, North Carolina 27834; and
6||National Exposure Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711#N#

Tóm tắt

Từ khóa


Tài liệu tham khảo

(1994), Dose–response assessment for developmental toxicity: II. Comparison of generic benchmark dose estimates with no observed adverse effect levels, Toxicol. Sci, 23, 487

(2006), Pharmacokinetic modeling of saturable, renal resorption of perfluoroalkylacids in monkeys—probing the determinants of long plasma half-lives, Toxicology, 227, 156, 10.1016/j.tox.2006.08.004

(2011), Consideration of dosimetry in evaluation of ToxCast™ data, J. Appl. Toxicol, 31, 741, 10.1002/jat.1626

(2010), Rate of decline in serum PFOA concentrations after granular activated carbon filtration at two public water systems in Ohio and West Virginia, Environ. Health Perspect, 118, 222, 10.1289/ehp.0901252

(1995), CODA: Convergence Diagnosis and Output Analysis for Gibbs Sampling Output

(2003), The conduct of in vitro and in vivo drug-drug interaction studies: A PhRMA perspective, J. Clin. Pharmacol, 43, 443, 10.1177/0091270003252519

(2010), Biokinetic modeling and in vitro–in vivo extrapolations, J. Toxicol. Environ. Health B Crit. Rev, 13, 242, 10.1080/10937404.2010.483940

(2010), Mode of action considerations in the quantitative assessment of tumour responses in the liver, Basic Clin. Pharmacol. Toxicol, 106, 173, 10.1111/j.1742-7843.2009.00505.x

(2002), Toxicity of ammonium perfluorooctanoate in male cynomolgus monkeys after oral dosing for 6 months, Toxicol. Sci, 69, 244, 10.1093/toxsci/69.1.244

(2009), Gestational and lactational exposure to potassium perfluorooctanesulfonate (K+PFOS) in rats: Developmental neurotoxicity, Reprod. Toxicol, 27, 319, 10.1016/j.reprotox.2008.12.010

(2004), The reproductive toxicology of ammonium perfluorooctanoate (APFO) in the rat, Toxicology, 196, 95, 10.1016/j.tox.2003.11.005

(2004), Pharmacokinetics of perfluorooctanoate in cynomolgus monkeys, Toxicol. Sci, 82, 394, 10.1093/toxsci/kfh302

(2007), Serum concentrations of 11 polyfluoroalkyl compounds in the U.S. population: Data from the National Health and Nutrition Examination Survey (NHANES) 1999–2000, Environ. Sci. Technol, 41, 2237, 10.1021/es062686m

(2009), Gestational and lactational exposure to potassium perfluorooctanesulfonate (K+PFOS) in rats: Toxicokinetics, thyroid hormone status, and related gene expression, Reprod. Toxicol, 27, 387, 10.1016/j.reprotox.2009.01.005

(2008), Thyroid hormone status and pituitary function in adult rats given oral doses of perfluorooctanesulfonate (PFOS), Toxicology, 243, 330, 10.1016/j.tox.2007.10.014

(2012), Comparative pharmacokinetics of perfluorooctanesulfonate (PFOS) in rats, mice, and monkeys, Reprod. Toxicol, 33, 428, 10.1016/j.reprotox.2011.07.002

(2012), Prenatal PFOS exposure induces oxidative stress and apoptosis in the lung of rat off-spring, Reprod. Toxicol, 33, 538, 10.1016/j.reprotox.2011.03.003

(2008), Altered fatty acid homeostasis and related toxicologic sequelae in rats exposed to dietary potassium perfluorooctanesulfonate (PFOS), J. Toxicol. Environ. Health. A, 71, 1526, 10.1080/15287390802361763

(1993), Physiological parameters in laboratory animals and humans, Pharm. Res, 10, 1093, 10.1023/A:1018943613122

(2008), Perfluorooctanoic acid-induced immunomodulation in adult C57BL/6J or C57BL/6N female mice, Environ. Health Perspect, 116, 644, 10.1289/ehp.10896

(2009), Chronic effects of perfluorooctanesulfonate exposure on immunotoxicity in adult male C57BL/6 mice, Arch. Toxicol, 83, 805, 10.1007/s00204-009-0424-0

(2004), Bayesian Data Analysis, 2nd ed

(2010), Levels of perfluorooctane sulfonate and perfluorooctanoic acid in female serum samples from Japan in 2008, Korea in 1994–2008 and Vietnam in 2007–2008 Gelman 2004 is located in Boca Raton, FL, Chemosphere, 79, 314

(1970), Monte Carlo sampling methods using Markov chains and their applications, Biometrika, 57, 97, 10.1093/biomet/57.1.97

(2009), Time trends and the influence of age and gender on serum concentrations of perfluorinated compounds in archived human samples, Environ. Sci. Technol, 43, 2131, 10.1021/es802827u

(1983), Simulation run length control in the presence of an initial transient, Oper. Res, 31, 1109, 10.1287/opre.31.6.1109

(2012), Perfluorinated chemical controls, Chem. Eng. News, 90, 24, 10.1021/cen-09037-govpol

(2009), Profiling bioactivity of the ToxCast chemical library using BioMAP primary human cell systems, J. Biomol. Screen, 14, 1054, 10.1177/1087057109345525

(2010), In vitro screening of environmental chemicals for targeted testing prioritization: The ToxCast project, Environ. Health Perspect, 118, 485, 10.1289/ehp.0901392

(2011), Estimating toxicity-related biological pathway altering doses for high-throughput chemical risk assessment, Chem. Res. Toxicol, 24, 451, 10.1021/tx100428e

(2003)

(2003), Perfluorooctanoic Acid: Toxicokinetics in the Rat. USEPA Administrative Record AR-226.1499

(2011), Environmental impact on vascular development predicted by high-throughput screening, Environ. Health Perspect, 119, 1596, 10.1289/ehp.1103412

(2011), Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets, Toxicology, 282, 1, 10.1016/j.tox.2010.12.010

(2011), Disruption of embryonic vascular development in predictive toxicology, Birth Defects Res. C Embryo Today Rev, 93, 312, 10.1002/bdrc.20223

(2002), Sex hormone-regulated renal transport of perfluorooctanoic acid, Chem. Biol. Interact, 139, 301, 10.1016/S0009-2797(02)00006-6

(2007), Perfluoroalkyl acids: A review of monitoring and toxicological findings, Toxicol. Sci, 99, 366, 10.1093/toxsci/kfm128

(2004), The developmental toxicity of perfluoroalkyl acids and their derivatives, Toxicol. Appl. Pharmacol, 198, 231, 10.1016/j.taap.2003.11.031

(2006), Effects of perfluorooctanoic acid exposure during pregnancy in the mouse, Toxicol. Sci, 90, 510, 10.1093/toxsci/kfj105

(2003), Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. II: Postnatal evaluation, Toxicol. Sci, 74, 382, 10.1093/toxsci/kfg122

(2011), Evaluation and prediction of pharmacokinetics of PFOA and PFOS in the monkey and human using a PBPK model, Regul. Toxicol. Pharmacol, 59, 157, 10.1016/j.yrtph.2010.12.004

(2009), Modeling single and repeated dose pharmacokinetics of PFOA in mice, Toxicol. Sci, 107, 331, 10.1093/toxsci/kfn234

(2005), Two-generation reproduction and cross-foster studies of perfluorooctanesulfonate (PFOS) in rats, Toxicology, 215, 126, 10.1016/j.tox.2005.07.018

(2005), Neonatal mortality from in utero exposure to perfluorooctanesulfonate (PFOS) in Sprague–Dawley rats: Dose–response, and biochemical and pharamacokinetic parameters, Toxicology, 215, 149, 10.1016/j.tox.2005.07.019

(2010), Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA’s ToxCast program, Chem. Res. Toxicol, 23, 578, 10.1021/tx900325g

(2009), Profiling chemicals based on chronic toxicity results from the U.S. EPA ToxRef Database, Environ. Health Perspect, 117, 392, 10.1289/ehp.0800074

(2011), Predictive model of rat reproductive toxicity from ToxCast high throughput screening, Biol. Reprod, 85, 327, 10.1095/biolreprod.111.090977

(1953), Equation of state calculations by fast computing machines, J. Chem. Phys, 21, 1087, 10.1063/1.1699114

vitro–in vivo extrapolation: estimation of human serum concentrations of chemicals equivalent to cytotoxic concentrations in vitro, 211

(2007), Half-life of serum elimination of perfluorooctanesulfonate, perfluorohexanesulfonate, and perfluorooctanoate in retired fluorochemical production workers, Environ. Health Perspect, 115, 1298, 10.1289/ehp.10009

(2012), Temporal trends of perfluoroalkyl concentrations in American Red Cross adult blood donors, 2000–2010, Environ. Sci. Technol, 46, 6330, 10.1021/es300604p

(2008), Suppression of humoral immunity in mice following exposure to perfluorooctane sulfonate, Toxicol. Sci, 104, 144, 10.1093/toxsci/kfn059

(2004), 13-Week dietary toxicity study of ammonium perfluorooctanoate (APFO) in male rats, Drug Chem. Toxicol, 27, 361, 10.1081/DCT-200039773

R Development Core Team, (2012), R: A Language and Environment for Statistical Computing, Version 2.10.0

(2010), Endocrine profiling and prioritization of environmental chemicals using ToxCast data, Environ. Health Perspect, 118, 1714, 10.1289/ehp.1002180

(2009), Pharmacokinetic modeling of perfluorooctanoic acid during gestation and lactation in the mouse, Reprod. Toxicol, 27, 373, 10.1016/j.reprotox.2009.02.009

(2003), Sub-chronic dietary toxicity of potassium perfluorooctanesulfonate in rats, Toxicology, 183, 117, 10.1016/S0300-483X(02)00511-5

(2002), Subchronic toxicity studies on perfluorooctanesulfonate potassium salt in cynomolgus monkeys, Toxicol. Sci, 68, 249, 10.1093/toxsci/68.1.249

(2011), Predictive models of prenatal developmental toxicity from ToxCast high-throughput screening data, Toxicol. Sci, 124, 109, 10.1093/toxsci/kfr220

(2010), Solving differential equations in R: Package deSolve, J. Stat. Softw, 33, 1

(2003), Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. I: Maternal and prenatal evaluations, Toxicol. Sci, 74, 369, 10.1093/toxsci/kfg121

(2010)

(2009), The beta-secretase enzyme BACE in health and Alzheimer’s disease: Regulation, cell biology, function, and therapeutic potential, J. Neurosci, 29, 12787, 10.1523/JNEUROSCI.3657-09.2009

(2008), Comparing models for perfluorooctanoic acid pharmacokinetics using Bayesian analysis, J. Pharmacokinet. Pharmacodyn, 35, 683, 10.1007/s10928-008-9108-2

(2009), Effects of perfluorooctanoic acid on mouse mammary gland development and differentiation resulting from cross-foster and restricted gestational exposures, Reprod. Toxicol, 27, 289, 10.1016/j.reprotox.2008.11.054

(2007), Developmental toxicity of perfluorooctanoic acid in the CD-1 mouse after cross-foster and restricted gestational exposures, Toxicol. Sci, 95, 462

(2010), Male reproductive system parameters in a two-generation reproduction study of ammonium perfluorooctanoate in rats and human relevance, Toxicology, 271, 64, 10.1016/j.tox.2010.03.005

(2012), Modeling in vitro cell-based assays experiments: Cell population dynamics, Models of the Ecological Hierarchy From Molecules to the Ecosphere, 51