Dosage regime experiments with oxolinic acid and flumequine in Atlantic salmon (Salmo salar L) held in seawater

1987, 331 Austin, 1983, Control of furunculosis by oxolinic acid, Aquaculture, 31, 101, 10.1016/0044-8486(83)90305-8 Barnes, 1990, In vitro activities of 4-quinolones against the fish pathogen Aeromonas salmonicida, Antimicrob. Agents Chemother., 34, 1819, 10.1128/AAC.34.9.1819 Barnes, 1991, Bactericidal activity of quinolones, including flumequine, against Aeromonas salmonicida, Proc. O.I.E.-Meet. “Problems of Chemotherapy in Aquaculture: From Theory to Reality”, Paris, 287 Barnes, 1991, In vitro susceptibility of the fish pathogen Aeromonas salmonicida to flumequine, Antimicrob. Agents Chemother., 35, 2634, 10.1128/AAC.35.12.2634 Björklund, 1992, Temperature-related absorption and excretion of oxolinic acid in rainbow trout (Oncorhynchus mykiss), Aquaculture, 102, 17, 10.1016/0044-8486(92)90285-S Blaser, 1987, Comparative study with enoxacin and netilmicin in a pharmacodynamic model to determine importance of ratio of antibiotic peak concentration to MIC for bactericidal activity and emergence of resistance, Antimicrob. Agents Chemother., 31, 1054, 10.1128/AAC.31.7.1054 Boon, 1991, Disposition of flumequine in plasma of European eel (Anguilla anguilla) after a single intramuscular injection, Aquaculture, 99, 213, 10.1016/0044-8486(91)90242-Y Chevalier, 1981, Distribution et cinitique tissulaire de la flumèquine chez la truite arc-en-ciel (Salmo gairdneri, Richardson), Rech. Residus. Rev. Med. Vet., 132, 831 Cravedi, 1987, Digestibility of chloramphenicol, oxolinic acid and oxytetracucline in rainbow trout and influence of these antibiotics on lipid digestibility, Aquaculture, 60, 133, 10.1016/0044-8486(87)90305-X Droy, 1990, Bioavailability, disposition and pharmacokinetics of 14 C-ormethoprim in rainbow trout (Salmo gairdneri), Xenobiotica, 20, 147, 10.3109/00498259009047150 Elema, 1994, Multiple-dose pharmacokinetic study of flumequine in Atlantic salmon (Salmo salar L.), Aquaculture, 128, 1, 10.1016/0044-8486(94)90096-5 Elema, 1995, Bioavailability of flumequine after oral administration to Atlantic salmon (Salmo salar L), Aquaculture, 136, 209, 10.1016/0044-8486(95)01049-1 Ellingsen, O.F., Nordby, K.-E., Rasmussen, K.E., 1989. Pharmaceutical dosage form for the medication of fish. International patent application no. PCT/N089/00059. Endo, 1973, Application of oxolinic acid as a chemotherapeutic agent against infectious disease in fish: I. Antibacterial activity, chemotherapeutic affect and pharmacokinetic effect of oxolinic acid in fish, Bull. Jpn. Soc. Sci. Fish., 39, 165, 10.2331/suisan.39.165 Endo, 1973, Application of oxolinic acid as chemotherapeutic agent against infectious disease in fish: II. Study of chemotherapeutic effect by hole body autobacteriography, Bull. Jpn. Soc. Sci. Fish., 39, 173, 10.2331/suisan.39.173 Grave, 1996, Comparison in prescribing patterns of antibacterial drugs in salmonid farming in Norway during the periods 1980–1988 and 1989–1994, J. Vet. Pharmacol. Ther., 19, 184, 10.1111/j.1365-2885.1996.tb00037.x Hustvedt, 1991, Absorption, distribution and elimination of oxolinic acid in Atlantic salmon (Salmo salar L) after various routes of administration, Aquaculture, 95, 193, 10.1016/0044-8486(91)90086-M Hustvedt, 1991, Bioavailability of oxolinic acid in Atlantic salmon (Salmo salar L) from medicated feed, Aquaculture, 97, 305, 10.1016/0044-8486(91)90322-X Hustvedt, 1991, Does oral administration of oxolinic acid or oxytetracycline effect feed intake of rainbow trout?, Aquaculture, 92, 109, 10.1016/0044-8486(91)90012-V Hustvedt, 1992, Combating cold-water vibriosis in Atlantic salmon (Salmo salar L) with oxolinic acid: a case report, Aquaculture, 103, 213, 10.1016/0044-8486(92)90167-J Ishida, 1992, Tissue levels of oxolinic acid after oral or intravascular administration to freshwater and seawater rainbow trout, Aquaculture, 102, 9, 10.1016/0044-8486(92)90284-R Kleinow, 1988, A review of the pharmacokinetics and metabolism of sulfadimethoxine in the rainbow trout (Salmo gairdneri), Vet. Hum. Toxicol., 30, 26 Malvisi, 1997, Tissue distribution of flumequine after in-feed administration in sea bream (Sparus aurata), Aquaculture, 157, 197, 10.1016/S0044-8486(97)00160-9 Martinsen, B., 1993. Quinolones as antimicrobial drugs in aquaculture, Antimicrobial activities and pharmacokinetic properties. Dr. sci. thesis, Norwegian College of Veterinary Medicine, Ås, Norway. Martinsen, 1995, Comparative single-dose pharmacokinetics of four quinolones, oxolinic acid, flumequine, sarafloxacin and enrofloxacin in Atlantic salmon (Salmo salar) held in seawater at 10 °C, Antimicrob. Agents Chemother., 39, 1059, 10.1128/AAC.39.5.1059 Martinsen, 1992, Temperature dependent in vitro antimicrobial activity of four 4-quinolones and oxytetracycline against bacteria pathogenic to fish, Antimicrob. Agents Chemother., 36, 1738, 10.1128/AAC.36.8.1738 Martinsen, 1994, Multiple-dose pharmacokinetic and depletion studies of sarafloxacin in Atlantic salmon (Salmo salar L), J. Fish Dis., 17, 111, 10.1111/j.1365-2761.1994.tb00204.x Nordmo, 1998, Evaluation of florfenicol in Atlantic salmon, Salmo salar L.: efficacy against furunculosis due to Aeromonas salmonicida and cold water vibriosis due to Vibrio salmonicida, J. Fish Dis., 21, 289, 10.1046/j.1365-2761.1998.00106.x O'Grady, 1988, Bath administration of quinolone antibiotic flumequine to brown trout Salmo trutta and Atlantic salmon S. salar, Dis. Aquat. Org., 4, 27, 10.3354/dao004027 Rasmussen, 1989, Solid-phase extraction and high-performance liquid chromatographic determination of flumequine and oxolinic acid in salmon plasma, J. Chromatogr., 496, 355, 10.1016/S0378-4347(00)82583-9 Rodgers, 1983, Oxolinic acid for control of enteric red-mouth disease in rainbow trout, Vet. Rec., 112, 83, 10.1136/vr.112.4.83 Rogstad, 1989, Simultaneous extraction and determination of oxolinic acid and flumequine in fish tissues by high performance liquid chromatography, J. Liq. Chromatogr., 12, 3073 Rogstad, 1993, Pharmacokinetics and bioavailability of flumequine and oxolinic acid after various routs of administration to Atlantic salmon in seawater, Aquaculture, 110, 207, 10.1016/0044-8486(93)90369-A Samuelsen, 1997, Single dose pharmacokinetic study of flumequine after intravenous, intraperitoneal and oral administration to Atlantic halibut (Hippoglossus hippoglossus) held in seawater at 9 °C, Aquaculture, 158, 215, 10.1016/S0044-8486(97)00190-7 Samuelsen, 1999, A single dose pharmacokinetic study of oxolinic acid and vetoquinol, an oxolinic acid ester, in Atlantic halibut Hippoglossus hippoglossus L held in seawater at 9 °C, J. Fish Dis., 22, 13, 10.1046/j.1365-2761.1999.00133.x Samuelsen, 1997, Multiple-dose pharmacokinetic study of Romet 30 in Atlantic salmon (Salmo salar) and in vitro antibacterial activity against Aeromonas salmonicida, Aquaculture, 152, 13, 10.1016/S0044-8486(96)01508-6 Samuelsen, 1999, Efficacy of Orally Administered Oxolinic acid and Vetoquinol, an oxolinic acid ester, for the treatment of Furunculosis in Atlantic salmon Salmo salar held in seawater, Dis. Aquat. Org., 37, 53, 10.3354/dao037053 Samuelsen, 2000, Single dose pharmacokinetic study of oxolinic acid and vetoquinol, an oxolinic acid ester, in Atlantic salmon (Salmo salar) held in seawater and in vitro antibacterial activity against Aeromonas salmonicida, Aquaculture, 187, 213, 10.1016/S0044-8486(00)00315-X Stamm, 1989, In vitro resistance by fish pathogens to aquacultural antibacterials, including the quinolones difloxacin (A-56619) and sarafloxacin (A-56620), J. Aquat. Anim. Health, 1, 135, 10.1577/1548-8667(1989)001<0135:IVRBFP>2.3.CO;2 Ueno, 1988, Levels of oxolinic acid in cultured rainbow trout and amago salmon after oral administration, Nippon Suisan Gakkaishi, 54, 485, 10.2331/suisan.54.485 Wolfson, 1989, Mechanisms of action and resistance to quinolone antimicrobial agents, 5