Donor-specific transfusion via the portal venous route induces prolongation of H-2-compatible but not H-2-incompatible cardiac graft survival

Transplant International - Tập 2 - Trang 199-202 - 1989
D. Górecki1, M. Jakóbisiak2, M. Łupińska1, A. Kruszewski1, J. Czyźyk1
1Department of Histology and Embryology, Institute of Biostructure, Medical School, Warsaw, Poland
2Department of Transplantology, Institute of Biostructure, Medical School, Warsaw, Poland

Tóm tắt

In the H-2-compatible donor-recipient combination (BALB/c→DBA/2), pretransplant donor-specific blood transfusion (DST) via the portal venous (PV) route significantly prolonged cardiac graft survival. DST via the intravenous (IV) route (systemic circulation) also showed a marked prolongation of heart tissue transplant survival in this model. In the H-2-incompatible combination (BALB/c→CBA/H), DST via the IV — but not via the PV — route resulted in accelerated graft rejection.

Tài liệu tham khảo

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