Donor-specific transfusion via the portal venous route induces prolongation of H-2-compatible but not H-2-incompatible cardiac graft survival
Tóm tắt
In the H-2-compatible donor-recipient combination (BALB/c→DBA/2), pretransplant donor-specific blood transfusion (DST) via the portal venous (PV) route significantly prolonged cardiac graft survival. DST via the intravenous (IV) route (systemic circulation) also showed a marked prolongation of heart tissue transplant survival in this model. In the H-2-incompatible combination (BALB/c→CBA/H), DST via the IV — but not via the PV — route resulted in accelerated graft rejection.
Tài liệu tham khảo
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