Does epigenetics have a role in age related macular degeneration and diabetic retinopathy?

Genes and Diseases - Tập 8 - Trang 279-286 - 2021
S. Mohana Devi1, I. Mahalaxmi2, J. Kaavya2, V. Chinnkulandhai3, V. Balachandar4
1SN ONGC Department of Genetics and Molecular Biology, Vision Research Foundation, Sankara Nethralaya, 41/18, College Road, Chennai, 600006, India
2Department of Zoology, Avinashilingam Institute for Home Science and Higher Education for Women, Avinashilingam University for Women, Coimbatore, Tamil Nadu, 641046, India
3Department of Biochemistry, Dr.N.G.P Arts and Science College, Coimbatore, Tamil Nadu, 641046, India
4Human Molecular Genetics and Stem Cells Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore, Tamil Nadu, 641046, India

Tài liệu tham khảo

Feinberg, 2007, Phenotypic plasticity and the epigenetics of human disease, Nature, 447, 433, 10.1038/nature05919 Willyard, 2010, The saving switch, Nat Med, 16, 18, 10.1038/nm0110-18 Skinner, 2010, Epigenetic transgenerational actions of environmental factors in disease etiology, TEM (Trends Endocrinol Metab), 21, 214, 10.1016/j.tem.2009.12.007 Xu, 2016, Epigenetics and cellular metabolism, Genet Epigenet, 8, 43, 10.4137/GEG.S32160 Bianchi, 2013, Hyperglycemia and vascular metabolic memory: truth or fiction?, Curr Diabetes Rep, 13, 403, 10.1007/s11892-013-0371-2 Pons, 2009, Epigenetic histone acetylation modifiers in vascular remodelling: new targets for therapy in cardiovascular disease, Eur Heart J, 33, 266, 10.1093/eurheartj/ehn603 Bird, 2002, DNA methylation patterns and epigenetic memory, Genes Dev, 16, 6, 10.1101/gad.947102 Reik, 2001, DNA methylation and mammalian epigenetics, Electrophoresis, 22, 2838, 10.1002/1522-2683(200108)22:14<2838::AID-ELPS2838>3.0.CO;2-M Tonna, 2010, Metabolic memory and diabetic nephropathy: potential role for epigenetic mechanisms, Nat Rev Nephrol, 6, 332, 10.1038/nrneph.2010.55 Sharma, 2014, Why AMD is a disease of ageing and not of development: mechanisms and insights, Front Aging Neurosci, 6, 10.3389/fnagi.2014.00151 World Health Organization Sobrin, 2014, Nature and nurture- genes and environment- predict onset and progression of macular degeneration, Prog Retin Eye Res, 40, 1, 10.1016/j.preteyeres.2013.12.004 Muthiah, 2014, Adaptive optics imaging shows rescue of macula cone photoreceptors, Ophthalmol Times, 121, 430, 10.1016/j.ophtha.2013.10.008 Bharti, 2014, Developing cellular therapies for retinal degenerative diseases, Invest Ophthalmol Vis Sci, 55, 1191, 10.1167/iovs.13-13481 Suuronen, 2007, Epigenetic regulation of clusterin/apolipoprotein J expression in retinal pigment epithelial cells, Biochem Biophys Res Commun, 357, 397, 10.1016/j.bbrc.2007.03.135 Pennington, 2015, Epigenetic mechanisms of the aging human retina, J ExpNeurosc, 9, 51 Khan, 2016, Differentiating drusen: drusen and drusen-like appearances associated with ageing, age-related macular degeneration, inherited eye disease and other pathological processes, Prog Retin Eye Res, 53, 70, 10.1016/j.preteyeres.2016.04.008 Bernstein, 2007, The mammalian epigenome, Cell, 128, 669, 10.1016/j.cell.2007.01.033 Sedivy, 2008, Aging by epigenetics: a consequence of chromatin damage?, Exp Cell Res, 314, 1909, 10.1016/j.yexcr.2008.02.023 Gauthier, 2017, Epigenetics and signaling pathways in glaucoma, BioMed Res Int, 2017, 10.1155/2017/5712341 Sharma, 2018, Genetic and epigenetic insights into uveal melanoma, Clin Genet, 93, 952, 10.1111/cge.13136 Zhang, 2017, Diabetic retinopathy: reversibility of epigenetic modifications and new therapeutic targets, Cell Biosci, 7, 10.1186/s13578-017-0167-1 Kim, 2001, Histone deacetylase induces angiogenesis by negative regulation of tumour suppressor genes, Nat Med, 7, 437, 10.1038/86507 Wang, 2008, Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7, Proc Natl Acad Sci Unit States Am, 105, 7738, 10.1073/pnas.0802857105 He, 2013, Epigenetic mechanisms in ocular disease, Mol Vis, 19, 665 Wei, 2012, Hypomethylation of the IL17RC promoter associates with age related macular degeneration, Cell Rep, 2, 1151, 10.1016/j.celrep.2012.10.013 Oliver, 2013, Hypomethylation of the IL17RC promoter in peripheral blood leukocytes is not a hallmark of age-related macular degeneration, Cell Rep, 5, 1527, 10.1016/j.celrep.2013.11.042 Hunter, 2012, DNA methylation is associated with altered gene expression in AMD, Invest Ophthalmol Vis Sci, 53, 2089, 10.1167/iovs.11-8449 Gemenetzi, 2014, The role of epigenetics in age-related macular degeneration, Eye, 28, 1407, 10.1038/eye.2014.225 Jarrett, 2008, Mitochondrial DNA damage and its potential role in retinal degeneration, Prog Retin Eye Res, 27, 596, 10.1016/j.preteyeres.2008.09.001 Fedorova, 2008, Nuclear architecture and gene regulation, Biochim Biophys Acta, 1783, 2174, 10.1016/j.bbamcr.2008.07.018 Kouzarides, 2007, Chromatin modifications and their function, Cell, 128, 693, 10.1016/j.cell.2007.02.005 Nan, 1998, Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex, Nature, 393, 386, 10.1038/30764 Vavilala, 2014, Evaluation of anti-HIF and anti- angiogenic properties of honokiol for the treatment of ocular neovascular diseases, PloS One, 9, 10.1371/journal.pone.0113717 Elmasry, 2018, Epigenetic modifications in hyperhomocysteinemia: potential role in diabetic retinopathy and age-related macular degeneration, Oncotarget, 9, 12562, 10.18632/oncotarget.24333 Gnana-Prakasam, 2013, Loss of Hfe leads to progression of tumor phenotype in primary retinal pigment epithelial cells, Invest Ophthalmol Vis Sci, 54, 63, 10.1167/iovs.12-10312 Suuronen, 2007, Epigenetic regulation of clusterin/apolipoprotein J expression in retinal pigment epithelial cells, Biochem Biophys Res Commun, 357, 397, 10.1016/j.bbrc.2007.03.135 Faith, 2014, Epigenetic modifications as potential therapeutic targets in age-related macular degeneration and diabetic retinopathy, Drug Discov Today, 19, 1387, 10.1016/j.drudis.2014.03.026 Frank, 2004, Diabetic retinopathy, N Engl J Med, 350, 48, 10.1056/NEJMra021678 Chilelli, 2013, AGEs, rather than hyperglycemia are responsible for microvascular complications in diabetes: a ‘‘glycoxidation-centric’’ point of view, Nutr Metabol Cardiovasc Dis, 23, 913, 10.1016/j.numecd.2013.04.004 Kowluru, 2010, Metabolic memory and diabetic retinopathy: role of inflammatory mediators in retinal pericytes, Exp Eye Res, 90, 617, 10.1016/j.exer.2010.02.006 Madsen-Bouterse, 2010, Role of mitochondrial DNA damage in the development of diabetic retinopathy and the metabolic memory phenomenon associated with its progression, Antioxidants Redox Signal, 13, 797, 10.1089/ars.2009.2932 Mishra, 2014, Retinal mitochondrial DNA mismatch repair in the development of diabetic retinopathy and its continued progression after termination of hyperglycemia, Invest Ophthalmol Vis Sci, 55, 6960, 10.1167/iovs.14-15020 Santos, 2011, Role of mitochondria biogenesis in the metabolic memory associated with the continued progression of diabetic retinopathy and its regulation by lipoic acid, Invest Ophthalmol Vis Sci, 52, 8791, 10.1167/iovs.11-8203 Santos, 2013, Impaired transport of mitochondrial transcription factor A (TFAM) and the metabolic memory phenomenon associated with the progression of diabetic retinopathy, Diabetes/Metab Res Rev., 29, 204, 10.1002/dmrr.2384 Santos, 2014, Posttranslational modification of mitochondrial transcription factor A in impaired mitochondria biogenesis: implications in diabetic retinopathy and metabolic memory phenomenon, Exp Eye Res, 121, 168, 10.1016/j.exer.2014.02.010 Kowluru, 2015, Oxidative stress and epigenetic modifications in the pathogenesis of diabetic retinopathy, Prog Retin Eye Res, 48, 40, 10.1016/j.preteyeres.2015.05.001 Kowluru, 2017, Diabetic retinopathy, metabolic memory and epigenetic modifications, Vis Res, 139, 30, 10.1016/j.visres.2017.02.011 Zawia, 2009, Epigenetics, oxidative stress, and Alzheimer disease, Free Radic Biol Med, 46, 1241, 10.1016/j.freeradbiomed.2009.02.006 White, 2010, Effect of prior intensive therapy in type 1 diabetes on 10-year progression of retinopathy in the DCCT/EDIC: comparison of adults and adolescents, Diabetes, 59, 1244, 10.2337/db09-1216 Reddy, 2015, Epigenetic mechanisms in diabetic complications and metabolic memory, Diabetologia, 58, 443, 10.1007/s00125-014-3462-y Tewari, 2012, Mitochondria DNA replication and DNA methylation in the metabolic memory associated with continued progression of diabetic retinopathy, Invest Ophthalmol Vis Sci, 53, 4881, 10.1167/iovs.12-9732 Zhong, 2013, Epigenetic modification of Sod 2 in the development of diabetic retinopathy and in the metabolic memory: role of histone methylation, Invest Ophthalmol Vis Sci, 54, 244, 10.1167/iovs.12-10854 Mishra, 2015, Epigenetic modification of mitochondrial DNA in the development of diabetic retinopathy, Invest Ophthalmol Vis Sci, 56, 5133, 10.1167/iovs.15-16937 Agardh, 2015, Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathy, BMC Med, 13, 10.1186/s12916-015-0421-5 Shan, 2016, Dynamic epigenetic modifications of retinal matrix metalloproteinase-9 in the development of diabetic retinopathy, Lab Invest, 96, 1040, 10.1038/labinvest.2016.78 Tewari, 2012, Damaged mitochondrial DNA replication system and the development of diabetic retinopathy, Antioxidants Redox Signal, 17, 492, 10.1089/ars.2011.4333 Maghbooli, 2014, Aberrant DNA methylation patterns in diabetic nephropathy, J Diabetes Metab Disord, 13, 10.1186/2251-6581-13-69 Zou, 2013, Hypermethylation of the prkcz gene in type 2 diabetes mellitus, J Diabetes Res, 2013, 10.1155/2013/721493 Santos, 2012, A compensatory mechanism protects retinal mitochondria from initial insult in diabetic retinopathy, Free Radic Biol Med, 53, 1729, 10.1016/j.freeradbiomed.2012.08.588 Kowluru, 2016, Dynamic DNA methylation of matrix metalloproteinase-9 in the development of diabetic retinopathy, Lab Invest, 96, 1040, 10.1038/labinvest.2016.78 Syreeni, 2011, Genetic examination of SETD7 and SUV39H1/H2 methyltransferases and the risk of diabetes complications in patients with type 1 diabetes, Diabetes, 60, 3073, 10.2337/db11-0073 Zhong, 2011, Epigenetic changes in mitochondrial superoxide dismutase in the retina and the development of diabetic retinopathy, Diabetes, 60, 1304, 10.2337/db10-0133 Kowluru, 2003, Diabetes-induced mitochondrial dysfunction in the retina, Invest Ophthalmol Vis Sci, 44, 5327, 10.1167/iovs.03-0353 Mishra, 2018, Sirt1-a guardian of the development of diabetic retinopathy, Diabetes, 67, 745, 10.2337/db17-0996