Do senescence markers correlate in vitro and in situ within individual human donors?
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Hayflick, 1965, The limited in vitro lifetime of human diploid cell strains., Exp Cell Res, 3, 614, 10.1016/0014-4827(65)90211-9
Moorhead, 1961, The serial cultivation of human diploid cell strains., Exp Cell Res, 2, 585, 10.1016/0014-4827(61)90192-6
Krizhanovsky, 2014, Physiological and pathological consequences of cellular senescence., Cell Mol Life Sci, 7, 4373, 10.1007/s00018-014-1691-3
van Deursen, 2011, Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders., Nature, 47, 232, 10.1038/nature10600
Keyes, 2013, Senescence is a developmental mechanism that contributes to embryonic growth and patterning., Cell, 15, 1119, 10.1016/j.cell.2013.10.041
Serrano, 2013, Programmed cell senescence during mammalian embryonic development., Cell, 15, 1104, 10.1016/j.cell.2013.10.019
Campisi, 2008, Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor., PLoS Biol, 6, 2853, 10.1371/journal.pbio.0060301
Lowe, 2008, Senescence of activated stellate cells limits liver fibrosis., Cell, 13, 657, 10.1016/j.cell.2008.06.049
Campisi, 1995, A biomarker that identifies senescent human cells in culture and in aging skin in vivo., Proc Natl Acad Sci USA, 9, 9363, 10.1073/pnas.92.20.9363
Stewart, 2008, Senescence: the good the bad and the dysfunctional., Curr Opin Genet Dev, 1, 42, 10.1016/j.gde.2007.12.002
Hwang, 2006, Senescence-associated beta-galactosidase is lysosomal beta-galactosidase., Aging Cell, 5, 187, 10.1111/j.1474-9726.2006.00199.x
Ferbeyre, 2009, Mitochondrial dysfunction contributes to oncogene-induced senescence., Mol Cell Biol, 2, 4495, 10.1128/MCB.01868-08
Boege, 2014, The hallmarks of fibroblast ageing., Mech Ageing Dev, 13, 26, 10.1016/j.mad.2014.03.004
Maier, 2011, Relation between maximum replicative capacity and oxidative stress-induced responses in human skin fibroblasts in vitro., J Gerontol A Biol Sci Med Sci, 6, 45, 10.1093/gerona/glq159
Maier, 2009, Rapid flow cytometric method for measuring senescence associated beta-galactosidase activity in human fibroblasts., Cytometry A, 7, 910, 10.1002/cyto.a.20796
Sedivy, 2004, Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)., Mol Cell, 1, 501, 10.1016/S1097-2765(04)00256-4
Passos, 2010, Quantitative assessment of markers for cell senescence., Exp Gerontol, 4, 772, 10.1016/j.exger.2010.01.018
Giovannelli, 2016, Long-term Neuroglial Cocultures as a Brain Aging Model: Hallmarks of Senescence, MicroRNA Expression Profiles, and Comparison With In Vivo Models., J Gerontol A Biol Sci Med Sci, 7, 50, 10.1093/gerona/glu231
Allen, 2002, Effects of establishing cell cultures and cell culture conditions on the proliferative life span of human fibroblasts isolated from different tissues and donors of different ages., Exp Cell Res, 27, 275, 10.1006/excr.2002.5485
Macieira-Coelho, 1982, Heterogeneity of the kinetics of proliferation within human skin fibroblastic cell populations., J Cell Sci, 5, 177
Grove, 1979, Human skin fibroblasts derived from papillary and reticular dermis: differences in growth potential in vitro., Science, 20, 526, 10.1126/science.432659
Jendrach, 2007, Identification of cultivation-independent markers of human endothelial cell senescence in vitro., Biogerontology, 8, 383, 10.1007/s10522-007-9082-x
Schmitt, 2014, In vivo and in vitro analysis of age-associated changes and somatic cellular senescence in renal epithelial cells., PLoS One, 9, e88071, 10.1371/journal.pone.0088071
King, 2008, Low oxygen delays fibroblast senescence despite shorter telomeres., Biogerontology, 9, 19, 10.1007/s10522-007-9113-7
Sharpless, 2013, Monitoring tumorigenesis and senescence in vivo with a p16(INK4a)-luciferase model., Cell, 15, 340, 10.1016/j.cell.2012.12.010
Sharpless, 2014, p16INK4a reporter mice reveal age-promoting effects of environmental toxicants., J Clin Invest, 12, 169, 10.1172/JCI70960
Sharpless, 2009, INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis., PLoS One, 4, e5027, 10.1371/journal.pone.0005027
Westendorp, 2002, Common chronic diseases and general impairments as determinants of walking disability in the oldest-old population., J Am Geriatr Soc, 5, 1405, 10.1046/j.1532-5415.2002.50363.x
van Heemst, 2007, Persistence of high-replicative capacity in cultured fibroblasts from nonagenarians., Aging Cell, 6, 27, 10.1111/j.1474-9726.2006.00263.x
Westendorp, 2006, Evidence of genetic enrichment for exceptional survival using a family approach: the Leiden Longevity Study., Eur J Hum Genet, 1, 79, 10.1038/sj.ejhg.5201508
Maier, 2012, Microarray-based identification of age-dependent differences in gene expression of human dermal fibroblasts., Mech Ageing Dev, 13, 498, 10.1016/j.mad.2012.06.002
Maier, 2012, Chronic inhibition of the respiratory chain in human fibroblast cultures: differential responses related to subject chronological and biological age., J Gerontol A Biol Sci Med Sci, 6, 456, 10.1093/gerona/glr196
Maier, 2016, DNA damage markers in dermal fibroblasts in vitro reflect chronological donor age., Aging (Albany NY), 8, 147, 10.18632/aging.100890
Westendorp, 2009, Stress-induced responses of human skin fibroblasts in vitro reflect human longevity., Aging Cell, 8, 595, 10.1111/j.1474-9726.2009.00506.x