Distribution of transferrin, ferritin, and lactoferrin in human tissues.

Journal of Clinical Pathology - Tập 31 Số 4 - Trang 316-327 - 1978
D Y Mason1,2, C R Taylor1,2
1Department of Hematopathology, University of Southern California School of Medicine, Los Angeles, California 90033, USA.
2From the Department ofPathology, Gibson Laboratories, Radcliffe Infirmary, Oxford, UK

Tóm tắt

An immunoperoxidase staining technique was used for detecting three major iron-binding proteins (transferrin, ferritin, and lactoferrin) in routine histological paraffin sections of human tissue. Transferrin was found mainly in hepatocytes, a variety of epithelial and myoepithelial cells, renal tubular cells, and histiocytes. Ferritin was most readily found in histiocytes and liver cells, with weaker reactions seen in epithelial cells. Lactoferrin was found in lactating breast tissue, bronchial glands, polymorphs, and gastric and duodenal epithelial cells. The technique is potentially valuable for investigating abnormal iron states.

Từ khóa


Tài liệu tham khảo

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Journal of Clinical Pathology

Tập 31 Số 4

316-327

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