Distinct features of SARS-CoV-2-specific IgA response in COVID-19 patients

European Respiratory Journal - Tập 56 Số 2 - Trang 2001526 - 2020
Hai-qiong Yu1,2, Bao Sun3,2, Zhang Fang4,1,3,2, Jin-cun Zhao3,2, Xiaoyu Liu1,2, Yi Min Li3,2, Xi-zhuo Sun4,2, Hong-feng Liang2,5, Bei Zhong6,2, Zehan Huang3,2, Pei-yan Zheng3, Li-feng Tian7, Hui‐Qi Qu7, De-chen Liu8, Er-yi Wang4,1, Xiao-jun Xiao1, Shi-yue Li3, Feng Ye3, Li Guan4, Dong Hu8, Håkon Håkonarson7,9,10, Zhi Gang Liu10,1, Nan-shan Zhong10,3
1State Key Laboratory of Respiratory Disease for Allergy at Shenzhen University, Shenzhen Key Laboratory of Allergy and Immunology, Shenzhen University School of Medicine, Shenzhen, China
2these authors contributed equally to this work
3State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
4Dept of Respirology and Allergy, Third Affiliated Hospital of Shenzhen University, Shenzhen, China
5Yangjiang People’s Hospital, Yangjiang, China
6Dept of Infectious Disease, The Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Qingyuan, China
7Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA;
8Dept of Preventive Medicine, Shenzhen University Health Sciences Center, Shenzhen, China
9Divisions of Human Genetics and Pulmonary Medicine, Dept of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
10Hakon Hakonarson, Zhi-gang Liu and Nan-shan Zhong are joint lead authors

Tóm tắt

Từ khóa


Tài liệu tham khảo

Sanche, 2020, High contagiousness and rapid spread of severe acute respiratory syndrome coronavirus 2, Emerging Infect Dis, 26, 1470, 10.3201/eid2607.200282

10.1016/S0140-6736(20)30185-9

Liu, 2019, Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection, JCI Insight, 4, 123158, 10.1172/jci.insight.123158

Guidelines for the Diagnosis and Treatment of Novel Coronavirus (2019-nCoV) Infection by the National Health Commission (Trial Version 7). http://www.gov.cn/zhengce/zhengceku/2020-03/04/content_5486705.htm Date last accessed: 4 May 2020. Date last updated: 3 March 2020.

10.1111/j.1469-0691.2004.01009.x

10.1016/j.autrev.2012.10.012

Arakawa, 2019, Secretory immunoglobulin A induces human lung fibroblasts to produce inflammatory cytokines and undergo activation, Clin Exp Immunol, 195, 287, 10.1111/cei.13253

10.1016/0008-8749(81)90435-4

10.1111/j.1365-2249.2005.02779.x

10.1016/j.molimm.2006.03.014

Leong, 2014, The unexplored roles of human serum IgA, DNA Cell Biol, 33, 823, 10.1089/dna.2014.2639

10.1016/j.immuni.2008.11.008

10.1038/mi.2014.121

Lee, 2016, Retinoic acid enhances lactoferrin-induced IgA responses by increasing betaglycan expression, Cell Mol Immunol, 13, 862, 10.1038/cmi.2015.73

Danzi, 2020, Acute pulmonary embolism and COVID-19 pneumonia: a random association?, Eur Heart J, 41, 1858, 10.1093/eurheartj/ehaa254