Distinct Dendritic Cell Populations Sequentially Present Antigen to CD4 T Cells and Stimulate Different Aspects of Cell-Mediated Immunity

Aida, 1990, Removal of endotoxin from protein solutions by phase separation using Triton X-114, J. Immunol. Methods, 132, 191, 10.1016/0022-1759(90)90029-U

Anjuere, 1999, Definition of dendritic cell subpopulations present in the spleen, Peyer' patches, lymph nodes, and skin of the mouse, Blood, 93, 590, 10.1182/blood.V93.2.590

Ardavin, 2001, Origin and differentiation of dendritic cells, Trends Immunol., 22, 691, 10.1016/S1471-4906(01)02059-2

Asselin-Paturel, 2001, Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology, Nat. Immunol., 2, 1145, 10.1038/ni736

Balfour, 1974, Proceedings, Monogr. Allergy, 8, 27

Banchereau, 1998, Dendritic cells and the control of immunity, Nature, 392, 245, 10.1038/32588

den Haan, 2000, CD8(+) but not CD8(−) dendritic cells cross-prime cytotoxic T cells in vivo, J. Exp. Med., 192, 1685, 10.1084/jem.192.12.1685

Dittel, 1999, Presentation of the self antigen myelin basic protein by dendritic cells leads to experimental autoimmune encephalomyelitis, J. Immunol., 163, 32, 10.4049/jimmunol.163.1.32

Ebnet, 1996, Orchestrated information transfer underlying leukocyte endothelial interactions, Annu. Rev. Immunol., 14, 155, 10.1146/annurev.immunol.14.1.155

Geissmann, 2002, Accumulation of immature Langerhans cells in human lymph nodes draining chronically inflamed skin, J. Exp. Med., 196, 417, 10.1084/jem.20020018

Gretz, 2000, Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex, J. Exp. Med., 192, 1425, 10.1084/jem.192.10.1425

Grubin, 1997, Deficient positive selection of CD4 T cells in mice displaying altered repertoires of MHC class II-bound self-peptides, Immunity, 7, 197, 10.1016/S1074-7613(00)80523-3

Henri, 2001, The dendritic cell populations of mouse lymph nodes, J. Immunol., 167, 741, 10.4049/jimmunol.167.2.741

Huleatt, 1995, Antigen-driven induction of CD11c on intestinal intraepithelial lymphocytes and CD8+ T cells in vivo, J. Immunol., 154, 5684, 10.4049/jimmunol.154.11.5684

Inaba, 1998, Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells, J. Exp. Med., 188, 2163, 10.1084/jem.188.11.2163

Inaba, 2000, The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli, J. Exp. Med., 191, 927, 10.1084/jem.191.6.927

Ingulli, 1997, In vivo detection of dendritic cell antigen presentation to CD4+ T cells, J. Exp. Med., 185, 2133, 10.1084/jem.185.12.2133

Ingulli, 2002, In situ analysis reveals physical interactions between CD11b+ dendritic cells and antigen-specific CD4 T cells after subcutaneous injection of antigen, J. Immunol., 169, 2247, 10.4049/jimmunol.169.5.2247

Jenkins, 2001, In vivo activation of antigen-specific CD4 T cells, Annu. Rev. Immunol., 19, 23, 10.1146/annurev.immunol.19.1.23

Kamath, 2002, Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs, Blood, 100, 1734, 10.1182/blood.V100.5.1734.h81702001734_1734_1741

Khoruts, 1998, A natural immunological adjuvant enhances T cell clonal expansion through a CD28-dependent, interleukin (IL)-2-independent mechanism, J. Exp. Med., 187, 225, 10.1084/jem.187.2.225

Kneitz, 1995, Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice, Eur. J. Immunol., 25, 2572, 10.1002/eji.1830250925

Lyons, 1994, Determination of lymphocyte division by flow cytometry, J. Immunol. Methods, 171, 131, 10.1016/0022-1759(94)90236-4

Macatonia, 1987, Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer flourescein isothiocyanate, J. Exp. Med., 166, 1654, 10.1084/jem.166.6.1654

Macher, 1969, Studies on the sensitization of animals with simple chemical compounds. XI. The fate of labeled picryl chloride and dinitrochlorobenzene after sensitizing injections, J. Exp. Med., 129, 103, 10.1084/jem.129.1.103

Manickasingham, 2000, Microbial and T cell-derived stimuli regulate antigen presentation by dendritic cells in vivo, J. Immunol., 165, 5027, 10.4049/jimmunol.165.9.5027

Matz, 1999, Fluorescent proteins from nonbioluminescent Anthozoa species, Nat. Biotechnol., 17, 969, 10.1038/13657

Mellman, 2001, Dendritic cells, Cell, 106, 255, 10.1016/S0092-8674(01)00449-4

Merica, 2000, Antigen-experienced CD4 T cells display a reduced capacity for clonal expansion in vivo that is imposed by factors present in the immune host, J. Immunol., 164, 4551, 10.4049/jimmunol.164.9.4551

Muderspach, 2000, A phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar intraepithelial neoplasia who are HPV 16 positive, Clin. Cancer Res., 6, 3406

Murphy, 1992, Monoclonal antibody detection of a major self peptide. MHC class II complex, J. Immunol., 148, 3483, 10.4049/jimmunol.148.11.3483

Nakano, 2001, CD11c(+)B220(+)GR-1(+) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells, J. Exp. Med., 194, 1171, 10.1084/jem.194.8.1171

Norbury, 2002, Visualizing priming of virus-specific CD8+ T cells by infected dendritic cells in vivo, Nat. Immunol., 3, 265, 10.1038/ni762

Palframan, 2001, Inflammatory chemokine transport and presentation in HEV, J. Exp. Med., 194, 1361, 10.1084/jem.194.9.1361

Picker, 1993, Lymphoid tissues and organs

Pooley, 2001, Intravenous soluble antigen is presented to CD4 T cells by CD8(−) dendritic cells, but cross-presented to CD8 T cells by CD8(+) dendritic cells, J. Immunol., 166, 5327, 10.4049/jimmunol.166.9.5327

Randolph, 2002, Is maturation required for Langerhans cell migration?, J. Exp. Med., 196, 413, 10.1084/jem.20021240

Refaeli, 1998, Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis, Immunity, 8, 615, 10.1016/S1074-7613(00)80566-X

Reinhardt, 2001, Visualizing the generation of memory CD4 T cells in the whole body, Nature, 410, 101, 10.1038/35065111

Reinhardt, 2003, Preferential accumulation of antigen-specific effector CD4 T cells at an antigen injection site involves CD62E-dependent migration but not local proliferation, J. Exp. Med., 197, 751, 10.1084/jem.20021690

Reis e Sousa, 1999, Analysis of adjuvant function by direct visualization of antigen presentation in vivo, J. Immunol., 162, 6552, 10.4049/jimmunol.162.11.6552

Roake, 1995, Dendritic cell loss from nonlymphoid tissues after systemic administration of lipopolysaccharide, tumor necrosis factor, and interleukin 1, J. Exp. Med., 181, 2237, 10.1084/jem.181.6.2237

Rudensky, 1991, On the complexity of self, Nature, 353, 660, 10.1038/353660a0

Ruedl, 2000, Anatomical origin of dendritic cells determines their life span in peripheral lymph nodes, J. Immunol., 165, 4910, 10.4049/jimmunol.165.9.4910

Ruedl, 2001, In vivo-matured Langerhans cells continue to take up and process native proteins unlike in vitro-matured counterparts, J. Immunol., 166, 7178, 10.4049/jimmunol.166.12.7178

Salomon, 1998, Three populations of mouse lymph node dendritic cells with different origins and dynamics, J. Immunol., 160, 708, 10.4049/jimmunol.160.2.708

Sato, 2001, Signaling events following chemokine receptor ligation in human dendritic cells at different developmental stages, Int. Immunol., 13, 167, 10.1093/intimm/13.2.167

Steinman, 1997, Dendritic cells in the T-cell areas of lymphoid organs, Immunol. Rev., 156, 25, 10.1111/j.1600-065X.1997.tb00956.x

Stewart, 1989, Bacterial toxins affect early events of T lymphocyte activation, J. Clin. Invest., 83, 234, 10.1172/JCI113865

Stoll, 2002, Dynamic imaging of T cell-dendritic cell interactions in lymph nodes, Science, 296, 1873, 10.1126/science.1071065

Turley, 2000, Transport of peptide-MHC class II complexes in developing dendritic cells, Science, 288, 522, 10.1126/science.288.5465.522

Vermaelen, 2001, Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes, J. Exp. Med., 193, 51, 10.1084/jem.193.1.51

Vremec, 1997, Dendritic cell subtypes in mouse lymphoid organs, J. Immunol., 159, 565, 10.4049/jimmunol.159.2.565

Vremec, 1992, The surface phenotype of dendritic cells purified from mouse thymus and spleen, J. Exp. Med., 176, 47, 10.1084/jem.176.1.47

Yang, 1999, Beta-defensins, Science, 286, 525, 10.1126/science.286.5439.525