Discrete Small RNA-Generating Loci as Master Regulators of Transposon Activity in Drosophila

Abad, 2004, Genomic analysis of Drosophila melanogaster telomeres: full-length copies of HeT-A and TART elements at telomeres, Mol. Biol. Evol., 21, 1613, 10.1093/molbev/msh174

Aravin, 2001, Double-stranded RNA-mediated silencing of genomic tandem repeats and transposable elements in the D. melanogaster germline, Curr. Biol., 11, 1017, 10.1016/S0960-9822(01)00299-8

Aravin, 2003, The small RNA profile during Drosophila melanogaster development, Dev. Cell, 5, 337, 10.1016/S1534-5807(03)00228-4

Aravin, 2006, A novel class of small RNAs bind to MILI protein in mouse testes, Nature, 442, 203, 10.1038/nature04916

Biemont, 1990, Localization of P elements, copy number regulation, and cytotype determination in Drosophila melanogaster, Genet. Res., 56, 3, 10.1017/S0016672300028822

Blumenstiel, 2005, Evidence for maternally transmitted small interfering RNA in the repression of transposition in Drosophila virilis, Proc. Natl. Acad. Sci. USA, 102, 15965, 10.1073/pnas.0508192102

Bregliano, 1980, Hybrid dysgenesis in Drosophila melanogaster, Science, 207, 606, 10.1126/science.6766221

Bucheton, 1990, I transposable elements and I-R hybrid dysgenesis in Drosophila, Trends Genet., 6, 16, 10.1016/0168-9525(90)90044-7

Bucheton, 1995, The relationship between the flamenco gene and gypsy in Drosophila: how to tame a retrovirus, Trends Genet., 11, 349, 10.1016/S0168-9525(00)89105-2

Bucheton, 1984, The molecular basis of I-R hybrid dysgenesis in Drosophila melanogaster: identification, cloning, and properties of the I factor, Cell, 38, 153, 10.1016/0092-8674(84)90536-1

Carmell, 2002, The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis, Genes Dev., 16, 2733, 10.1101/gad.1026102

Castro, 2004, Drosophila melanogaster P transposable elements: mechanisms of transposition and regulation, Genetica, 121, 107, 10.1023/B:GENE.0000040382.48039.a2

Chen, 2005, The developmental miRNA profiles of zebrafish as determined by small RNA cloning, Genes Dev., 19, 1288, 10.1101/gad.1310605

Cox, 1998, A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal, Genes Dev., 12, 3715, 10.1101/gad.12.23.3715

Cox, 2000, piwi encodes a nucleoplasmic factor whose activity modulates the number and division rate of germline stem cells, Development, 127, 503, 10.1242/dev.127.3.503

Deng, 2002, miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis, Dev. Cell, 2, 819, 10.1016/S1534-5807(02)00165-X

Denli, 2004, Processing of primary microRNAs by the Microprocessor complex, Nature, 432, 231, 10.1038/nature03049

Desset, 2003, COM, a heterochromatic locus governing the control of independent endogenous retroviruses from Drosophila melanogaster, Genetics, 164, 501, 10.1093/genetics/164.2.501

Engels, 1979, Hybrid dysgenesis in Drosophila melanogaster: the biology of female and male sterility, Genetics, 92, 161, 10.1093/genetics/92.1.161

Girard, 2006, A germline-specific class of small RNAs binds mammalian Piwi proteins, Nature, 442, 199, 10.1038/nature04917

Grivna, 2006, MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis, Proc. Natl. Acad. Sci. USA, 103, 13415, 10.1073/pnas.0605506103

Hamilton, 1999, A species of small antisense RNA in posttranscriptional gene silencing in plants, Science, 286, 950, 10.1126/science.286.5441.950

Harris, 2001, Aubergine encodes a Drosophila polar granule component required for pole cell formation and related to eIF2C, Development, 128, 2823, 10.1242/dev.128.14.2823

Hoskins, 2002, Heterochromatic sequences in a Drosophila whole-genome shotgun assembly, Genome Biol., 3, 10.1186/gb-2002-3-12-research0085

Kalmykova, 2005, Argonaute protein PIWI controls mobilization of retrotransposons in the Drosophila male germline, Nucleic Acids Res., 33, 2052, 10.1093/nar/gki323

Karpen, 1992, Analysis of subtelomeric heterochromatin in the Drosophila minichromosome Dp1187 by single P element insertional mutagenesis, Genetics, 132, 737, 10.1093/genetics/132.3.737

Ketting, 1999, Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD, Cell, 99, 133, 10.1016/S0092-8674(00)81645-1

Kidwell, 1977, Hybrid dysgenesis in drosophila melanogaster: a syndrome of aberrant traits including mutation, sterility and male recombination, Genetics, 86, 813, 10.1093/genetics/86.4.813

Kuramochi-Miyagawa, 2004, Mili, a mammalian member of piwi family gene, is essential for spermatogenesis, Development, 131, 839, 10.1242/dev.00973

Lau, 2006, Characterization of the piRNA complex from rat testes, Science, 313, 363, 10.1126/science.1130164

Lin, 1997, A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the Drosophila ovary, Development, 124, 2463, 10.1242/dev.124.12.2463

Liu, 2004, Argonaute2 is the catalytic engine of mammalian RNAi, Science, 305, 1437, 10.1126/science.1102513

Marin, 2000, P-Element repression in Drosophila melanogaster by a naturally occurring defective telomeric P copy, Genetics, 155, 1841, 10.1093/genetics/155.4.1841

Megosh, 2006, The Role of PIWI and the miRNA Machinery in Drosophila Germline Determination, Curr. Biol., 16, 1884, 10.1016/j.cub.2006.08.051

Misra, 1990, Cytotype control of Drosophila P element transposition: the 66 kd protein is a repressor of transposase activity, Cell, 62, 269, 10.1016/0092-8674(90)90365-L

Pal-Bhadra, 1997, Cosuppression in Drosophila: gene silencing of Alcohol dehydrogenase by white-Adh transgenes is Polycomb dependent, Cell, 90, 479, 10.1016/S0092-8674(00)80508-5

Pal-Bhadra, 2002, RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila, Mol. Cell, 9, 315, 10.1016/S1097-2765(02)00440-9

Pelisson, 1981, The I–R system of hybrid dysgenesis in Drosophila melanogaster: are I factor insertions responsible for the mutator effect of the I–R interaction?, Mol. Gen. Genet., 183, 123, 10.1007/BF00270149

Pelisson, 1987, Evidence for rapid limitation of the I element copy number in a genome submitted to several generations of I-R hybrid dysgenesis in Drosophila melanogaster, Mol. Gen. Genet., 207, 306, 10.1007/BF00331594

Pelisson, 1994, Gypsy transposition correlates with the production of a retroviral envelope-like protein under the tissue-specific control of the Drosophila flamenco gene, EMBO J., 13, 4401, 10.1002/j.1460-2075.1994.tb06760.x

Pfeffer, 2005, Identification of microRNAs of the herpesvirus family, Nat. Methods, 2, 269, 10.1038/nmeth746

Prud'homme, 1995, Flamenco, a gene controlling the gypsy retrovirus of Drosophila melanogaster, Genetics, 139, 697, 10.1093/genetics/139.2.697

Reiss, 2004, aubergine mutations in Drosophila melanogaster impair P cytotype determination by telomeric P elements inserted in heterochromatin, Mol. Genet. Genomics, 272, 336, 10.1007/s00438-004-1061-1

Robert, 2001, Characterization of the flamenco region of the Drosophila melanogaster genome, Genetics, 158, 701, 10.1093/genetics/158.2.701

Roche, 1998, Trans-silencing by P elements inserted in subtelomeric heterochromatin involves the Drosophila Polycomb group gene, Enhancer of zeste, Genetics, 149, 1839, 10.1093/genetics/149.4.1839

Ronsseray, 1991, The maternally inherited regulation of P elements in Drosophila melanogaster can be elicited by two P copies at cytological site 1A on the X chromosome, Genetics, 129, 501, 10.1093/genetics/129.2.501

Ronsseray, 1998, Repression of hybrid dysgenesis in Drosophila melanogaster by combinations of telomeric P-element reporters and naturally occurring P elements, Genetics, 149, 1857, 10.1093/genetics/149.4.1857

Rubin, 1982, The molecular basis of P-M hybrid dysgenesis: the nature of induced mutations, Cell, 29, 987, 10.1016/0092-8674(82)90462-7

Saito, 2006, Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome, Genes Dev., 20, 2214, 10.1101/gad.1454806

Sarot, 2004, Evidence for a piwi-dependent RNA silencing of the gypsy endogenous retrovirus by the Drosophila melanogaster flamenco gene, Genetics, 166, 1313, 10.1534/genetics.166.3.1313

Savitsky, 2006, Telomere elongation is under the control of the RNAi-based mechanism in the Drosophila germline, Genes Dev., 20, 345, 10.1101/gad.370206

Sijen, 2001, On the role of RNA amplification in dsRNA-triggered gene silencing, Cell, 107, 465, 10.1016/S0092-8674(01)00576-1

Smyth, 1997, Gene silencing: cosuppression at a distance, Curr. Biol., 7, R793, 10.1016/S0960-9822(06)00407-6

Stuart, 2002, Telomeric P elements associated with cytotype regulation of the P transposon family in Drosophila melanogaster, Genetics, 162, 1641, 10.1093/genetics/162.4.1641

Tabara, 1999, The rde-1 gene, RNA interference, and transposon silencing in C. elegans, Cell, 99, 123, 10.1016/S0092-8674(00)81644-X

Vagin, 2006, A distinct small RNA pathway silences selfish genetic elements in the germline, Science, 313, 320, 10.1126/science.1129333