Discovery of tetrahydropalmatine and protopine regulate the expression of dopamine receptor D2 to alleviate migraine from Yuanhu Zhitong formula

Phytomedicine - Tập 91 - Trang 153702 - 2021
Xiaohui Zhang1, Yule Wang1, Kai Zhang2, Hongda Sheng1, Yuhan Wu1, Huimin Wu1, Yingchao Wang3, Jianli Guan4, Qingfen Meng4, Huahuan Li4, Zhenhao Li5, Guanwei Fan2,6,7, Yi Wang1,3,7
1Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
2First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China
3Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Hangzhou, China
4Henan Fusen Pharmaceutical Co., Ltd., Henan, China
5Zhejiang Key Agricultural Enterprise Institute of Shouxiangu Rare Herb Product, Zhejiang, China
6Tianjin Key Laboratory of Translational Research of TCM Prescription and Syndrome, Tianjin, China.
7State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China

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Phytomedicine

Tập 91

153702

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