Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling

Cell Chemical Biology - Tập 27 Số 1 - Trang 66-73.e7 - 2020
Inchul You1,2, Emily C. Erickson3, Katherine A. Donovan1,2, Nicholas A. Eleuteri2, Eric S. Fischer1,2, Nathanael S. Gray1,2, Alex Toker3
1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02215, USA
2Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA,
3Department of Pathology, Medicine and Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA

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