Discovery and mechanistic study of a photocatalytic indoline dehydrogenation for the synthesis of elbasvir

Chemical Science - Tập 7 Số 3 - Trang 2066-2073
Hatice G. Yayla1,2,3, Feng Peng4,5, Ian Mangion4,5, Mark McLaughlin4,5, Louis-Charles Campeau4,5, Ian W. Davies4,5, Daniel A. DiRocco4,5, Robert R. Knowles1,2,3
1Department of Chemistry, Princeton University, Princeton, New Jersey 08544, USA
2Princeton
3Princeton University
4Department of Process Chemistry, Merck & Co., Inc. Rahway, New Jersey 07065, USA
5Merck & Co., Inc., Rahway

Tóm tắt

Elbasvir is a potent NS5A antagonist for the treatment of chronic hepatitis C.

Từ khóa


Tài liệu tham khảo

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