Discontinuation of dasatinib in patients with chronic myeloid leukaemia who have maintained deep molecular response for longer than 1 year (DADI trial): a multicentre phase 2 trial
Jun Imagawa1, Hideo Tanaka2, Masaya Okada3, Hirohisa Nakamae4, Masayuki Hino5, Kazunori Murai5, Yoji Ishida5, Takashi Kumagai6, Seiichi Sato7, Kazuteru Ohashi8, Hisashi Sakamaki8, Hisashi Wakita9, Nobuhiko Uoshima10, Yasunori Nakagawa11, Yosuke Minami12, Masahiro Ogasawara13, Tomoharu Takeoka14, Hiroshi Akasaka15, Takahiko Utsumi16, Naokuni Uike17
1Department of Haematology and Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan
2Department of Haematology, Hiroshima City Asa Hospital, Hiroshima, Japan
3Division of Haematology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan
4Department of Haematology, Graduate School of Medicine, Osaka City University, Osaka, Japan
5Department of Haematology and Oncology, Iwate Medical University, Morioka, Japan
6Department of Haematology, Ohme Municipal General Hospital, Tokyo, Japan
7Department of Internal Medicine, Fujimoto Sogo Hospital, Miyakonojo, Japan
8Haematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Centre Komagome Hospital, Tokyo, Japan
9Division of Haematology and Oncology, Japanese Red Cross Narita Hospital, Narita, Japan
10Department of Haematology, Matsushita Memorial Hospital, Moriguchi, Osaka, Japan
11Department of Haematology, Japanese Red Cross Medical Centre, Tokyo, Japan
12Division of Blood Transfusion and Division of Medical Oncology and Haematology, Kobe University Hospital, Kobe, Japan
13Department of Haematology, Sapporo Hokuyu Hospital, Sapporo, Japan
14Division of Haematology and Immunology, Otsu Red Cross Hospital, Otsu, Japan
15Department of Haematology, Shinko Hospital, Kobe, Japan
16Department of Haematology, Shiga Medical Centre for Adults, Moriyama, Japan
17Division of Haematology, National Kyushu Cancer Centre, National Hospital Organisation, Fukuoka, Japan
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The Lancet Haematology
Tập 2
e528-e535
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