Direct detection of microRNA based on plasmon hybridization of nanoparticle dimers

Analyst, The - Tập 140 Số 4 - Trang 1140-1148
Yang Wang1,2,3,4, Elspeth MacLachlan1,5,3,4, Bach Kim Nguyen1,2,3,4, Guodong Fu1,5,3,4, Chun Peng1,5,3,4, Jennifer I. L. Chen1,2,3,4
1Canada M3J 1P3
2Department of Chemistry, York University, 4700 Keele Street, Toronto, ON, Canada M3J 1P3
3Toronto
4York University
5Department of Biology, York University, 4700 Keele Street, Toronto, ON, Canada M3J 1P3

Tóm tắt

We demonstrate the direct detection of microRNA-210, a biomarker for hypoxia-related diseases, in cellular RNA extracts and cell media using discrete actuatable plasmonic nanoparticle dimers.

Từ khóa


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