Dimethyl fumarate and vitamin D derivatives cooperatively enhance VDR and Nrf2 signaling in differentiating AML cells in vitro and inhibit leukemia progression in a xenograft mouse model

Matan Nachliely1, Aviram Trachtenberg1, Boris Khalfin1, Karen Nalbandyan2, Merav Cohen-Lahav3, Kaori Yasuda4, Toshiyuki Sakaki4, Andrzej Kutner5, Michael Danilenko1
1Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, 84105 Beer Sheva, Israel
2Department of Pathology, Soroka University Medical Center, and Faculty of Health Sciences, Ben-Gurion University of the Negev, 84105 Beer-Sheva, Israel
3Laboratory of Biochemistry, Soroka University Medical Center, 84101 Beer Sheva, Beer Sheva, Israel
4Department of Biotechnology, Faculty of Engineering, Toyama Prefectural University, 939-0398 Imizu, Toyama, Japan
5Department of Pharmacology, Pharmaceutical Research Institute, 01-793 Warsaw, Poland

Tài liệu tham khảo