Digital Twins in Health Care: Ethical Implications of an Emerging Engineering Paradigm

Koen Bruynseels1, Filippo Santoni de Sio1, Jeroen van den Hoven1
1Department of Philosophy, Faculty of Technology, Policy and Management, Delft University of Technology, Delft, Netherlands

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Allhoff, 2009, Ethics of human enhancement: an executive summary., Sci. Eng. Ethics, 17, 201, 10.1007/s11948-009-9191-9

Bostrom, 2008, “Ethical issues in human enhancement,” in, New Waves in Applied Ethics, 120

Brenner, 2012, Personalized medicine: words that mean just what you choose?, Mol. Ther., 20, 241, 10.1038/mt.2011.311

Burms, 1991, Natural kinds and moral distinctions., Philosophia, 21, 101, 10.1007/BF02381972

Daniels, 2000, Normal functioning and the treatment-enhancement distinction., Camb. Q. Health Ethics, 9, 309, 10.1017/S0963180100903037

Dupré, 1993, In J. Dupré, The Disorder of Things.

2017, Framingham Heart Study.

Fukuyama, 2002, Our Posthuman Future: : Consequences of the Biotechnology Revolution.

2017, Predix Technology Brief - Digital Twin.

Giubilini, 2015, The ethics of human enhancement., Philos. Compass, 10, 233, 10.1111/phc3.12208

Glaessgen, 2012, The Digital Twin Paradigm for Future NASA and U.S. Air Force Vehicles. 53rd Structures, Structural Dynamics, and Materials Conference: Special Session on the Digital Twin.

Hofmann, 2017, Limits to human enhancement: nature, disease, therapy or betterment?, BMC Med. Ethics, 18, 10.1186/s12910-017-0215-8

Hottois, 1996, “Entre symboles et technosciences. Un itinéraire philosophique,” in, Philosophie et Technosciences

Husain, 2011, Cognitive enhancement by drugs in health and disease., Cell, 15, 28, 10.1016/j.tics.2010.11.002

2016, The Future for Industrial Services: The Digital Twin.

Kahane, 2015, Normal human variation: refocusing the enhancement debate., Bioethics, 29, 133, 10.1111/bioe.12045

Kummar, 2015, Application of molecular profiling in clinical trials for advanced metastatic cancers., J. Natl. Cancer Inst., 107, 10.1093/jnci/djv003

Lange, 2010, The history of attention deficit hyperactivity disorder., Atten. Defic. Hyperact. Disord., 2, 241, 10.1007/s12402-010-0045-8

Lehrach, 2016, The Future of Health Care: Deep Data, Smart Sensors, Virtual Patients and the Internet-of-Humans.

Liang, 2015, CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes., Protein Cell, 6, 363, 10.1007/s13238-015-0153-5

Lloyd-Price, 2016, The healthy human microbiome., Genome Med., 8, 10.1186/s13073-016-0307-y

Menuz, 2013, Is human enhancement also a personal matter?, Sci. Eng. Ethics, 19, 161, 10.1007/s11948-011-9294-y

Miller, 2016, Biomarkers in heart failure: the importance of inconvenient details., ESC Heart Fail., 3, 3, 10.1002/ehf2.12071

Novell, 1990, From Da Vinci to Harvey: the development of mechanical analogy in medicine from 1500 to 1650., J. Royal Soc. Med., 83, 396, 10.1177/014107689008300620

Plümecke, 2016, Genes, symptoms and the “asymptomatic ill”: towards a broader understanding of genetic discrimination., New Genet. Soc., 35, 124, 10.1080/14636778.2016.1176525

2015, The Precision Medicine Initiative Cohort Program - Building A Research Foundation for the 21st Century Medicine.

2003, Beyond Therapy: Biotechnology and the Pursuit of Happiness.

2017, Project Baseline.

Santoni de Sio, 2016, Why less praise for enhanced performance? Moving beyond responsibility-shifting, authenticity, and cheating, towards a nature-of-activities approach., Cogn. Enhanc. Ethic. Policy Implic. Int., 10.1093/acprof:oso/9780199396818.003.0003

Savulescu, 2004, Why should we allow performance enhancing drugs in sports., Br. J. Sports Med., 38, 666, 10.1136/bjsm.2003.005249

Scoles, 2016, A Digital Twin of Your Body Could Become a Critical Part of Your Health Care.

2015, The digital Twin - Digitalization in Machine Building.

Singer, 1974, All animals are equal., Philos. Exch., 5, 103

Steinhubl, 2016, Digital medicine. Off the cuff: rebooting blood pressure treatment., Lancet, 388, 10.1016/S0140-6736(16)31348-4

Telenti, 2016, Deep sequencing of 10000 human genomes., PNAS, 113, 11901, 10.1073/pnas.1613365113

Temkin, 2011, “Is living longer living better?,” in, Enhancing Human Capacities, 10.1002/9781444393552.ch26

2017, Protocol v4 Genomics England.

Timmermans, 2011, Ethics and Nanopharmacy: value sensitive design of new drugs., Nanoethics, 5, 269, 10.1007/s11569-011-0135-x

van den Hoven, 2008, “Information technology, privacy, and the protection of personal data,” in, Information Technology and Moral philosophy, 301, 10.1017/CBO9780511498725.016

van den Hoven, 2012, Engineering and the problem of moral overload., Sci. Eng. Ethics, 18, 143, 10.1007/s11948-011-9277-z

Whitehouse, 1997, Enhancing cognition in the intellectually intact., Hastings Cent. Rep., 27, 14, 10.2307/3528662