Diflucortolone valerate loaded solid lipid nanoparticles as a semisolid topical delivery system

Fatma S. Abdel-Salam1, Seham A. Elkheshen2,3, Azza A. Mahmoud3,4, Hussein O. Ammar3,4
1Egyptian Patent Office, Academy of Research and Technology, Cairo, Egypt
2Department of Pharmaceutics, Faculty of Pharmacy, Cairo University, Cairo, Egypt
3Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences and Pharmaceutical Industries, Future University in Egypt, Cairo, Egypt
4Department of Pharmaceutical Technology, National Research Center, Dokki, Cairo, Egypt

Tài liệu tham khảo

Pardeike, 2009, Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products, Int J Pharm, 366, 170, 10.1016/j.ijpharm.2008.10.003 Pawar, 2012, Solid lipid nanoparticles; the beneficial carrier for the delivery of lipid soluble drugs, IJPRD, 3, 200 Jenning, 2000, Vitamin A loaded solid lipid nanoparticles for topical use: occlusive properties and drug targeting to the upper skin, Eur J Pharm Biopharm, 49, 211, 10.1016/S0939-6411(99)00075-2 Muller, 2000, Solid lipid nanoparticles (SLN) for controlled drug delivery – a review of the state of the art, Eur J Pharm Biopharm, 50, 161, 10.1016/S0939-6411(00)00087-4 Lippacher, 2002, Semisolid SLN dispersions for topical application: influence of formulation and production parameters on viscoelastic properties, Eur J Pharm Biopharm, 53, 155, 10.1016/S0939-6411(01)00233-8 Lippacher, 2001, Preparation of semisolid drug carriers for topical application based on solid lipid nanoparticles, Int J Pharm, 214, 9, 10.1016/S0378-5173(00)00623-2 Ozcan, 2013, Enhanced dermal delivery of diflucortolone valerate using lecithin/chitosan nanoparticles: in-vitro and in-vivo evaluations, Int J Nanomed, 8, 461, 10.2147/IJN.S40519 Coutinho, 2011, The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights, Mol Cell Endocrinol, 335, 2, 10.1016/j.mce.2010.04.005 Refai H. Studies on the parameters affecting hydrocortisone release and permeation through excised human stratum corneum with emphasis on the influence of dilution [Ph.D. thesis]. University of Carolo-Wilhelmina; 2001. Palabiyik, 2006, Liquid chromatographic and spectrophotometric determination of diflucortolone valerate and chlorquinaldol in creams, J Food Drug Anal, 15, 145 2012 Havlickova, 2008, The advantages of topical combination therapy in the treatment of inflammatory dermatomycoses, Mycoses, 51, 16, 10.1111/j.1439-0507.2008.01615.x Rawlins, 1977 Ekambaram, 2012, Solid lipid nanoparticles: a review, Sci Revs Chem Commun, 2, 80 Jensen, 2010, Corticosteroid solubility and lipid polarity control release from solid lipid nanoparticles, Int J Pharm, 390, 53, 10.1016/j.ijpharm.2009.10.022 Priyanka, 2012, Preparation and evaluation of montelukast sodium loaded solid lipid nanoparticles, J Young Pharm, 4, 129, 10.4103/0975-1483.100016 Niculae, 2013, Optimization of lipid nanoparticles composition for sunscreen encapsulation, UPB Sci Bull, 75, 79 Miner, 1993 Ammar, 2011, Preparation and evaluation of hydrogels as a vehicle for topical delivery of lornoxicam, IJDFR, 2, 254 Escobar-Chávez, 2006, Applications of thermo-reversible pluronic F-127 gels in pharmaceutical formulations, J Pharm Pharmaceut Sci, 9, 339 Illing, 2004, Investigation on the flow behavior of dispersion of solid triglyceride nanoparticles, Int J Pharm, 284, 123, 10.1016/j.ijpharm.2004.07.017 Boudreaux, 2002, Lipids Oh, 2002, Characterization and thermal stability of polymorphic forms of synthesized tristearin, Food Chem Toxicol, 67, 2911 Sinha, 2010, Solid lipid nanoparticles (SLN’s) – trends and implications in drug targeting, Int J Adv in Pharm Sci, 1, 212