Diffusion Tensor Imaging in Arginase Deficiency Reveals Damage to Corticospinal Tracts

Brusilow, 1996, Urea cycle disorders: diagnosis, pathophysiology, and therapy, Adv Pediatr, 43, 127 Applegarth, 2000, Incidence of inborn errors of metabolism in British Columbia, 1969-1996, Pediatrics, 105, e10, 10.1542/peds.105.1.e10 Prasad, 1997, Argininemia: a treatable genetic cause of progressive spastic diplegia simulating cerebral palsy: case reports and literature review, J Child Neurol, 12, 301, 10.1177/088307389701200502 Crombez, 2005, Hyperargininemia due to liver arginase deficiency, Mol Genet Metab, 84, 243, 10.1016/j.ymgme.2004.11.004 Cederbaum, 1979, Hyperargininemia with arginase deficiency, Pediatr Res, 13, 827, 10.1203/00006450-197907000-00007 Cowley, 1998, Adult-onset arginase deficiency, J Inherit Metab Dis, 21, 677, 10.1023/A:1005492819527 Cederbaum, 2004, Arginases I and II: do their functions overlap?, Mol Genet Metab, 81 Ludeman, 2008, Diffusion tensor imaging of the pyramidal tracts in infants with motor dysfunction, Neurology, 71, 1676, 10.1212/01.wnl.0000304084.59964.e2 Basser, 1994, MR diffusion tensor spectroscopy and imaging, Biophys J, 66, 259, 10.1016/S0006-3495(94)80775-1 Talairach, 1988 Woods, 1998, Automated image registration: I. General methods and intrasubject, intramodality validation, J Comput Assist Tomogr, 22, 139, 10.1097/00004728-199801000-00027 Mori, 2000, In vivo visualization of human neural pathways by magnetic resonance imaging, Ann Neurol, 47, 412, 10.1002/1531-8249(200003)47:3<412::AID-ANA28>3.0.CO;2-H Scaglia, 2006, Clinical, biochemical, and molecular spectrum of hyperargininemia due to arginase I deficiency, Am J Med Genet C Semin Med Genet, 142C, 113, 10.1002/ajmg.c.30091 Deignan, 2008, Increased plasma and tissue guanidino compounds in a mouse model of hyperargininemia, Mol Genet Metab, 93, 172, 10.1016/j.ymgme.2007.09.016