Diffferential sensitivity of in vivo TNF and IL-6 production to modulation by anti-inflammatory drugs in mice

Aggarwal, 1984, Human lymphotoxin. Production by a lymphoblastoid cell line, purification, and initial characterization, J. biol. Chem., 259, 686, 10.1016/S0021-9258(17)43716-1

Bertini, 1988, Adrenalectomy sensitizes mice to the lethal effects of interleukin 1 and tumor necrosis factor, J. exp. Med., 167, 1708, 10.1084/jem.167.5.1708

Beutler, 1986, Cachectin and tumor necrosis factor as two sides of the same biological coin, Nature, 320, 584, 10.1038/320584a0

Beutler, 1986, Control of cachectin (tumor necrosis factor) synthesis: mechanisms of endotoxin resistance, Science, 232, 977, 10.1126/science.3754653

Beutler, 1985, Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin, Science, 229, 869, 10.1126/science.3895437

Endres, 1989, In vitro production of IL 1 beta, IL 1 alpha, TNF and 1L2 in healthy subjects: distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation, Eur. J. Immun., 19, 2327, 10.1002/eji.1830191222

Gadina, 1991, Protective effect of chlorpromazine on endotoxin toxicity and TNF production in glucocorticoid-sensitive and glucocorticoid-resistant models of endotoxic shock, J. exp. Med., 173, 1305, 10.1084/jem.173.6.1305

Gauldie, 1987, Interferon beta2/B-cell stimulatory factor type 2 shares indentity with monocyte-derived hepatocyte-stimulating factor and regulates the major protein response in liver cells, 84, 7251

Hack, 1989, Increased plasma levels of interleukin-6 in sepsis, Blood, 74, 1704, 10.1182/blood.V74.5.1704.1704

Helle, 1988, Interleukin 6 is involved in interleukin 1-induced activities, Eur. J. Immun., 18, 957, 10.1002/eji.1830180619

Katakami, 1988, Regulation of tumour necrosis factor production by mouse peritoneal macrophages: the role of cellular cyclic AMP, Immunology, 64, 719

Kunkel, 1988, Prostaglandin E2 regulates macrophage-derived tumor necrosis factor gene expression, J. biol. Chem., 263, 5380, 10.1016/S0021-9258(18)60727-6

Martich, 1991, Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin: the effect of anti-inflammatory agents, J. exp. Med., 173, 1021, 10.1084/jem.173.4.1021

Shalaby, 1989, Endotoxin, tumor necrosis factor-alpha and interleukin 1 induce interleukin 6 production in vivo, Clin. Immun. Immunopath., 53, 488, 10.1016/0090-1229(89)90010-X

Sironi, 1989, IL-1 stimulates IL-6 production in endothelial cells, J. Immun., 142, 549, 10.4049/jimmunol.142.2.549

Spinas, 1991, Pretreatment with ibuprofen augments circulating tumor necrosis factor-alpha, interleukin-6, and elastase during acute endotoxinemia, J. infect. Dis., 163, 89, 10.1093/infdis/163.1.89

Starnes, 1990, Anti-IL-6 monoclonal antibodies protect against lethal Escherichia coli infection and lethal tumor necrosis factor-alpha challenge in mice, J. Immun., 145, 4185, 10.4049/jimmunol.145.12.4185

Ulich, 1991, Endotoxin-induced cytokine gene expression in vivo. III. IL-6 mRNA and serum protein expression and the in vivo hematologic effects of IL-6, J. Immun., 146, 2316, 10.4049/jimmunol.146.7.2316

Waage, 1989, The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1 and fatal outcome, J. exp. Med., 169, 333, 10.1084/jem.169.1.333

Waage, 1990, Glucocorticoids inhibit the production of IL 6 from monocytes, endothelial cells and fibroblasts, Eur. J. Immun., 20, 2439, 10.1002/eji.1830201112

Wise, 1980, Ibuprofen improves survival from endotoxic shock in the rat, J. Pharmac. exp. Ther., 215, 160

Zhang, 1988, Synthesis of interleukin 6 (interferon-beta2/B cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cyclic AMP, J. biol. Chem., 263, 6177, 10.1016/S0021-9258(18)68768-X

Zhang, 1988, Enhancement of cAMP levels and of protein kinase activity by tumor necrosis factor and interleukin 1 in human fibroblasts: role in the induction of interleukin 6, 85, 6802

Zilberstein, 1986, Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines, EMBO J., 5, 2529, 10.1002/j.1460-2075.1986.tb04531.x

Zuckerman, 1989, Differential regulation of lipopolysaccharide-induced interleukin 1 and tumor necrosis factor synthesis: effects of endogenous and exogenous glucocorticoids and the role of the pituitary - adrenal axis, Eur. J. Immun., 19, 301, 10.1002/eji.1830190213