Diffferential sensitivity of in vivo TNF and IL-6 production to modulation by anti-inflammatory drugs in mice

International Journal of Immunopharmacology - Tập 14 - Trang 1045-1050 - 1992
Marina Sironi1, Massimo Gadina1, Marcela Kankova1, Franca Riganti1, Alberto Mantovani1, Mario Zandalasini1, Pietro Ghezzi1
1“Mario Negri” Institute for Pharmacological Research, Via Eritrea 62, 20157 Milan, Italy

Tài liệu tham khảo

Aggarwal, 1984, Human lymphotoxin. Production by a lymphoblastoid cell line, purification, and initial characterization, J. biol. Chem., 259, 686, 10.1016/S0021-9258(17)43716-1 Bertini, 1988, Adrenalectomy sensitizes mice to the lethal effects of interleukin 1 and tumor necrosis factor, J. exp. Med., 167, 1708, 10.1084/jem.167.5.1708 Beutler, 1986, Cachectin and tumor necrosis factor as two sides of the same biological coin, Nature, 320, 584, 10.1038/320584a0 Beutler, 1986, Control of cachectin (tumor necrosis factor) synthesis: mechanisms of endotoxin resistance, Science, 232, 977, 10.1126/science.3754653 Beutler, 1985, Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin, Science, 229, 869, 10.1126/science.3895437 Endres, 1989, In vitro production of IL 1 beta, IL 1 alpha, TNF and 1L2 in healthy subjects: distribution, effect of cyclooxygenase inhibition and evidence of independent gene regulation, Eur. J. Immun., 19, 2327, 10.1002/eji.1830191222 Gadina, 1991, Protective effect of chlorpromazine on endotoxin toxicity and TNF production in glucocorticoid-sensitive and glucocorticoid-resistant models of endotoxic shock, J. exp. Med., 173, 1305, 10.1084/jem.173.6.1305 Gauldie, 1987, Interferon beta2/B-cell stimulatory factor type 2 shares indentity with monocyte-derived hepatocyte-stimulating factor and regulates the major protein response in liver cells, 84, 7251 Hack, 1989, Increased plasma levels of interleukin-6 in sepsis, Blood, 74, 1704, 10.1182/blood.V74.5.1704.1704 Helle, 1988, Interleukin 6 is involved in interleukin 1-induced activities, Eur. J. Immun., 18, 957, 10.1002/eji.1830180619 Katakami, 1988, Regulation of tumour necrosis factor production by mouse peritoneal macrophages: the role of cellular cyclic AMP, Immunology, 64, 719 Kunkel, 1988, Prostaglandin E2 regulates macrophage-derived tumor necrosis factor gene expression, J. biol. Chem., 263, 5380, 10.1016/S0021-9258(18)60727-6 Martich, 1991, Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin: the effect of anti-inflammatory agents, J. exp. Med., 173, 1021, 10.1084/jem.173.4.1021 Shalaby, 1989, Endotoxin, tumor necrosis factor-alpha and interleukin 1 induce interleukin 6 production in vivo, Clin. Immun. Immunopath., 53, 488, 10.1016/0090-1229(89)90010-X Sironi, 1989, IL-1 stimulates IL-6 production in endothelial cells, J. Immun., 142, 549, 10.4049/jimmunol.142.2.549 Spinas, 1991, Pretreatment with ibuprofen augments circulating tumor necrosis factor-alpha, interleukin-6, and elastase during acute endotoxinemia, J. infect. Dis., 163, 89, 10.1093/infdis/163.1.89 Starnes, 1990, Anti-IL-6 monoclonal antibodies protect against lethal Escherichia coli infection and lethal tumor necrosis factor-alpha challenge in mice, J. Immun., 145, 4185, 10.4049/jimmunol.145.12.4185 Ulich, 1991, Endotoxin-induced cytokine gene expression in vivo. III. IL-6 mRNA and serum protein expression and the in vivo hematologic effects of IL-6, J. Immun., 146, 2316, 10.4049/jimmunol.146.7.2316 Waage, 1989, The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1 and fatal outcome, J. exp. Med., 169, 333, 10.1084/jem.169.1.333 Waage, 1990, Glucocorticoids inhibit the production of IL 6 from monocytes, endothelial cells and fibroblasts, Eur. J. Immun., 20, 2439, 10.1002/eji.1830201112 Wise, 1980, Ibuprofen improves survival from endotoxic shock in the rat, J. Pharmac. exp. Ther., 215, 160 Zhang, 1988, Synthesis of interleukin 6 (interferon-beta2/B cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cyclic AMP, J. biol. Chem., 263, 6177, 10.1016/S0021-9258(18)68768-X Zhang, 1988, Enhancement of cAMP levels and of protein kinase activity by tumor necrosis factor and interleukin 1 in human fibroblasts: role in the induction of interleukin 6, 85, 6802 Zilberstein, 1986, Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines, EMBO J., 5, 2529, 10.1002/j.1460-2075.1986.tb04531.x Zuckerman, 1989, Differential regulation of lipopolysaccharide-induced interleukin 1 and tumor necrosis factor synthesis: effects of endogenous and exogenous glucocorticoids and the role of the pituitary - adrenal axis, Eur. J. Immun., 19, 301, 10.1002/eji.1830190213