Differential impacts of road diets on driving behavior among older adults with and without preclinical Alzheimer’s pathology

Adebisi, 2019, Age-related differences in motor-vehicle crash severity in California, Safety, 5, 48, 10.3390/safety5030048 Alrumaidhi, 2022, Factors affecting crash severity among elderly drivers: A multilevel ordinal logistic regression approach, Sustainability, 14, 10.3390/su141811543 Anstey, 2005, Cognitive, sensory and physical factors enabling driving safety in older adults, Clinical Psychology Review, 25, 45, 10.1016/j.cpr.2004.07.008 Arlinghaus, 2018, Advocating for behavior change with education, American Journal of Lifestyle Medicine, 12, 113, 10.1177/1559827617745479 Aschenbrenner, 2022, Neuropsychological correlates of changes in driving behavior among clinically healthy older adults, The Journals of Gerontology: Series B, 77, 1769, 10.1093/geronb/gbac101 Aschenbrenner, 2015, Interactive effects of working memory and trial history on Stroop interference in cognitively healthy aging, Psychology and Aging, 30, 1, 10.1037/pag0000012 Babulal, 2016, Creating a driving profile for older adults using GPS devices and naturalistic driving methodology, F1000Research, 5, 2376, 10.12688/f1000research.9608.2 Babulal, 2019, A naturalistic study of driving behavior in older adults and preclinical Alzheimer disease: A pilot study, Journal of Applied Gerontology, 38, 277, 10.1177/0733464817690679 Barthelemy, 2023, CSF tau phosphorylation occupancies at T217 and T205 represent improved biomarkers of amyloid and tau pathology in Alzheimer’s disease, Nature Aging, 10.1038/s43587-023-00380-7 Bayat, 2021, GPS driving: A digital biomarker for preclinical Alzheimer disease, Alzheimer's Research & Therapy, 13, 10.1186/s13195-021-00852-1 Boerwinkle, 2021, Temporal correlation of CSF and neuroimaging in the amyloid-Tau-neurodegeneration model of Alzheimer disease, Neurology, 10.1212/WNL.0000000000012123 Brewer, M., & Bedsole, L. (2015). Handbook for designing roadways for the aging population. US Department of Transportation Federal Highway Administration. Bugg, 2007, Age differences in stroop interference: contributions of general slowing and task-specific deficits, Aging, Neuropsychology, and Cognition, 14, 155, 10.1080/138255891007065 Carr, 2011, Predicting road test performance in drivers with dementia, Journal of the American Geriatrics Society, 59, 2112, 10.1111/j.1532-5415.2011.03657.x Center for Disease Control (2016). Life stages and populations. Coleman, 2015 Connell, 2013, Older adults’ driving reduction and cessation, Journal of Applied Gerontology, 32, 975, 10.1177/0733464812448962 Davis, 2001, Relating severity of pedestrian injury to impact speed in vehicle-pedestrian crashes: Simple threshold model, Transportation Research Record: Journal of the Transportation Research Board, 1773, 108, 10.3141/1773-13 Davis, 2020, Evaluation of naturalistic driving behavior using in-vehicle monitoring technology in preclinical and early Alzheimer’s disease, Frontiers in Psychology, 11, 10.3389/fpsyg.2020.596257 Dekker, S. W. A. (2000). The re-invention of human error. Eby, D. W., Molnar, L. J. & St. Louis, R. M. (2019). Perspectives and Strategies for promoting safe transportation among older adults. Elsevier. Eisenstein, 2012, Characterization of extrastriatal D2 in vivo specific binding of [18 F](N-methyl)benperidol using PET, Synapse, 66, 770, 10.1002/syn.21566 Fagan, 2006, Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta; 42 in humans, Annals of Neurology, 59, 512, 10.1002/ana.20730 Garber, 1988 Gaugler, 2020, 2020 Alzheimer’s disease facts and figures, Alzheimer’s and Dementia, 16, 391, 10.1002/alz.12068 Gordon, 2016, The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomography tau imaging, Brain, 139, 2249, 10.1093/brain/aww139 Hadfield, 2010, MCMC methods for multi-response generalized linear mixed models: The MCMCglmm R package, Journal of Statistical Software, 33, 10.18637/jss.v033.i02 Hajnal, 1995, A registration and interpolation procedure for subvoxel matching of serially acquired mr images, Journal of Computer Assisted Tomography, 19, 289, 10.1097/00004728-199503000-00022 Harmon, 2018, Planning for a nondriving Future: behaviors and beliefs among middle-aged and older drivers, Geriatrics, 3, 19, 10.3390/geriatrics3020019 Hemphill, E. (2021). Pedestrian deaths in St. Louis nearly doubled in 2020, fueling new push for safer streets. St. Louis Public Radio. Holden, 2009, People or systems? To blame is human. The fix is to engineer, Professional Safety, 54, 34 Huang, 2002, Evaluation of lane reduction ‘Road Diet’ measures on crashes and injuries, Transportation Research Record, 10.3141/1784-11 Huff, 2015, Dissociative global and local task-switching costs across younger adults, middle-aged adults, older adults, and very mild Alzheimer’s disease individuals, Psychology and Aging, 30, 727, 10.1037/pag0000057 Insel, 2021, Time between milestone events in the Alzheimer’s disease amyloid cascade, NeuroImage, 227, 10.1016/j.neuroimage.2020.117676 Insurance Institute for Highway Safety (2023). Older drivers: License renewal procedures. IIHS-HLDI Crash Testing and Highway Safety. Jack, C. R. et al. (2010). Hypothetical model of dynamic biomarkers of the Alzheimer’s pathological cascade. The Lancet Neurology, 9, 119–128. doi: 10.1016/S1474-4422(09)70299-6 (2010). Jack, C. R. et al. (2016). A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers. doi: 10.1212/WNL.0000000000002923. Joshi, 2009, Reducing between scanner differences in multi-center PET studies, NeuroImage, 46, 154, 10.1016/j.neuroimage.2009.01.057 Knapp, K. et al. (2014). Road diet informational guide. Larsson, P., & Tingvall, C. (2013). A road safety strategy based on human factors principles. In Engineering psychology and cognitive ergonomics. Applications and services: 10th international conference. Springer Berlin Heidelberg. Lim, 2022, Development of road diet segment and intersection crash modification factors, Transportation Research Record: Journal of the Transportation Research Board, 2676, 660, 10.1177/03611981211069074 Lippmann, 2015 Lynott, J. et al. (2009). Planning complete streets for an aging America. McCrory, S. et al. (2021). St. Louis city & county crash report. McKhann, 1984, Clinical diagnosis of Alzheimer’s disease: Report of the NINCDS-ADRDA Work Group* under the auspices of Department of Health and Human Services Task Force on Alzheimer’s Disease, Neurology, 34, 939, 10.1212/WNL.34.7.939 McLeroy, 1988, An ecological perspective on health promotion programs, Health Education Quarterly, 15, 351, 10.1177/109019818801500401 Mishra, 2017, AV-1451 PET imaging of tau pathology in preclinical Alzheimer disease: Defining a summary measure, NeuroImage, 161, 171, 10.1016/j.neuroimage.2017.07.050 Misokefalou, 2016, Evaluating driver distraction factors in urban motorways. A naturalistic study conducted in Attica Tollway, Greece, Transportation Research Procedia, 15, 771, 10.1016/j.trpro.2016.06.064 Missouri Department of Elementary and Secondary Education (2023). https://dese.mo.gov/college-career-readiness/curriculum/drivers-education. Missouri Department of Revenue (2023). The Missouri Driver License and Nondriver ID. https://dor.mo.gov/driver-license/. Molnar, L. J. et al. (2021). Identifying policy approaches to extending the safe mobility of older adults. Morris, 1997, Clinical dementia rating: A reliable and valid diagnostic and staging measure for dementia of the Alzheimer type, International Psychogeriatric Association, 9, 173, 10.1017/S1041610297004870 Noland, 2015, Costs and benefits of a road diet conversion, Case Studies in Transport Policy, 3, 449, 10.1016/j.cstp.2015.09.002 Palumbo, 2019, Driver licensing, motor-vehicle crashes, and moving violations among older adults, Journal of Safety Research, 71, 87, 10.1016/j.jsr.2019.09.019 Perneczky, 2023, Anti-amyloid antibody therapies in Alzheimer’s disease, Brain, 10.1093/brain/awad005 Rigdon, H., Atkinson, J., Bosack, J., O’Donnell, C., & Lambert, J. (2014). Noteworthy practices guide. In North American conference on elderly mobility. Roe, 2017, Preclinical Alzheimer’s disease and longitudinal driving decline, Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 3, 74 Roe, 2019, A 2.5-year longitudinal assessment of naturalistic driving in preclinical Alzheimer’s disease, Journal of Alzheimer’s Disease, 68, 1625, 10.3233/JAD-181242 Roe, 2022, Improving our understanding of driving changes in preclinical and early symptomatic Alzheimer’s disease: The role of naturalistic driving studies, Journal of Alzheimer's Disease Reports, 6, 521, 10.3233/ADR-220024 Roe, 2022, Driving, social distancing, protective, and coping behaviors of older adults before and during COVID-19, Journal of Applied Gerontology, 41, 1831, 10.1177/07334648221093851 Rousset, 1998, Correction for partial volume effects in PET: Principle and validation, Journal of Nuclear Medicine, 39, 904 Schindler, 2019, High-precision plasma β-amyloid 42/40 predicts current and future brain amyloidosis, Neurology, 93, E1647, 10.1212/WNL.0000000000008081 Schindler, 2021, Predicting symptom onset in sporadic Alzheimer disease with amyloid PET, Neurology, 97, e1823, 10.1212/WNL.0000000000012775 Schulz, 2004, Social determinants of health: Implications for environmental health promotion, Health Education & Behavior, 31, 455, 10.1177/1090198104265598 Su, 2013, Quantitative analysis of PiB-PET with FreeSurfer ROIs, PLoS One1, 8 Su, 2015, Partial volume correction in quantitative amyloid imaging, NeuroImage, 107, 55, 10.1016/j.neuroimage.2014.11.058 Su, 2016, Quantitative Amyloid imaging in autosomal Dominant Alzheimer’s disease: Results from the DIAN study group, PLoS One, 11, 10.1371/journal.pone.0163669 Thigpen, 2018, Driver’s licensing delay: A retrospective case study of the impact of attitudes, parental and social influences, and intergenerational differences, Transportation Research Part A: Policy and Practice, 111, 24 Tice, P., Dey Tirtha, S., & Eluru, N. (2021). Driver attention and the built environment initial, findings from a naturalistic driving study. Proceedings of the Human Factors and Ergonomics Society Annual Meeting, 65, 1077–1081. Ulak, 2017, Spatial investigation of aging-involved crashes: A GIS-based case study in Northwest Florida, Journal of Transport Geography, 58, 71, 10.1016/j.jtrangeo.2016.11.011 van Dam, 2023 Vivoda, 2021, Planning for driving retirement: The effect of driving perceptions, driving events, and assessment of driving alternatives, Transportation Research Part F: Traffic Psychology and Behaviour, 76, 193, 10.1016/j.trf.2020.11.007 Vivoda, 2016, The influence of the transportation environment on driving reduction and cessation, The Gerontologist, 10.1093/geront/gnw088