Differential expression and function of the Drosophila Pax6 genes eyeless and twin of eyeless in embryonic central nervous system development

Brand, 1993, Targeted gene expression as a means of altering cell fates and generating dominant phenotypes, Development, 118, 401, 10.1242/dev.118.2.401

Bridges, 1935, The mutants and linkage data of chromosome four of Drosophila melanogaster, Z. Biol., 4, 401

Broadie, 1995, Syntaxin and synaptobrevin function downstream of vesicle docking in Drosophila, Neuron, 15, 663, 10.1016/0896-6273(95)90154-X

Callahan, 1994, Tau-beta-galactosidase, an axon-target fusion protein, Proc. Natl. Acad. Sci. USA, 91, 5972, 10.1073/pnas.91.13.5972

Campbell, 1994, RK2, a glial-specific homeodomain protein required for embryonic nerve cord condensation viability in Drosophila, Development, 120, 2957, 10.1242/dev.120.10.2957

Campos-Ortega, 1997

Caric, 1997, Determination of the migratory capacity of embryonic cortical cells lacking the transcription factor Pax-6, Development, 124, 5087, 10.1242/dev.124.24.5087

Czerny, 1995, DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5), Mol. Cell. Biol., 15, 2858, 10.1128/MCB.15.5.2858

Czerny, 1999, twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development, Mol. Cell, 3, 297, 10.1016/S1097-2765(00)80457-8

Dahl, 1997, Pax genes and organogenesis, Bioessays, 19, 755, 10.1002/bies.950190905

Eaton, 1990, Repression of ci-D in posterior compartments of Drosophila by engrailed, Genes Dev., 4, 1068, 10.1101/gad.4.6.1068

Engelkamp, 1999, Role of Pax6 in development of the cerebellar system, Development, 126, 3585, 10.1242/dev.126.16.3585

Fire, 1998, Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans, Nature, 391, 806, 10.1038/35888

Fujita, 1982, Monoclonal antibodies against the Drosophila nervous system, Proc. Natl. Acad. Sci. USA, 79, 7929, 10.1073/pnas.79.24.7929

Glardon, 1997, Conservation of Pax-6 in a lower chordate, the ascidian Phallusia mammillata, Development, 124, 817, 10.1242/dev.124.4.817

Glaser, 1994, PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous defects, Nat. Genet., 7, 463, 10.1038/ng0894-463

Gorfinkiel, 1997, The homeobox gene Distal-less induces ventral appendage development in Drosophila, Genes Dev., 11, 2259, 10.1101/gad.11.17.2259

Grieder, 1997, Synergistic activation of a Drosophila enhancer by HOM/EXD and DPP signaling, EMBO J., 16, 7402, 10.1093/emboj/16.24.7402

Grindley, 1995, The role of Pax-6 in eye and nasal development, Development, 121, 1433, 10.1242/dev.121.5.1433

Halder, 1995, Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila, Science, 267, 1788, 10.1126/science.7892602

Halder, 1995, New perspectives on eye evolution, Curr. Opin. Genet. Dev., 5, 602, 10.1016/0959-437X(95)80029-8

Hartmann, 2000, Expression, regulation and function of the homeobox gene empty spiracles in brain and ventral nerve cord development of Drosophila, Mech. Dev., 90, 143, 10.1016/S0925-4773(99)00237-3

Hill, 1991, Mouse small eye results from mutations in a paired-like homeobox-containing gene, Nature, 354, 522, 10.1038/354522a0

Hirth, 1995, Developmental defects in brain segmentation caused by mutations of the homeobox genes orthodenticle and empty spiracles in Drosophila, Neuron, 15, 769, 10.1016/0896-6273(95)90169-8

Hirth, 1998, Homeotic gene action in embryonic brain development of Drosophila, Development, 125, 1579, 10.1242/dev.125.9.1579

Hoge, 1915, Another gene in the fourth chromosome of Drosophila, Am. Nat., 49, 47, 10.1086/279455

Jan, 1982, Antibodies to horseradish peroxidase as specific neuronal markers in Drosophila and grasshopper embryos, Proc. Natl. Acad. Sci. USA, 79, 2700, 10.1073/pnas.79.8.2700

Kennerdell, 1998, Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway, Cell, 95, 1017, 10.1016/S0092-8674(00)81725-0

Klaes, 1994, The Ets transcription factors encoded by the Drosophila gene pointed direct glial cell differentiation in the embryonic CNS, Cell, 78, 149, 10.1016/0092-8674(94)90581-9

Kurusu, 2000, Genetic control of development of the mushroom bodies, the associative learning centers in the Drosophila brain, by the eyeless, twin of eyeless, and Dachshund genes, Proc. Natl. Acad. Sci. USA, 97, 2140, 10.1073/pnas.040564497

Lin, 1994, Ectopic and increased expression of Fasciclin II alters motoneuron growth cone guidance, Neuron, 13, 507, 10.1016/0896-6273(94)90022-1

Martini, 2000, The retinal determination gene dachshund is required for mushroom body cell differentiation, Development, 127, 2663, 10.1242/dev.127.12.2663

Mastick, 1997, Pax-6 functions in boundary formation and axon guidance in the embryonic mouse forebrain, Development, 124, 1985, 10.1242/dev.124.10.1985

Misquitta, 1999, Targeted disruption of gene function in Drosophila by RNA interference (RNA-i): a role for nautilus in embryonic somatic muscle formation, Proc. Natl. Acad. Sci. USA, 96, 1451, 10.1073/pnas.96.4.1451

Nelson, 1984, Aniridia. A review, Surv. Ophthalmol., 28, 621, 10.1016/0039-6257(84)90184-X

Noll, 1993, Evolution and role of Pax genes, Curr. Opin. Genet. Dev., 3, 595, 10.1016/0959-437X(93)90095-7

Noveen, 2000, Early development of the Drosophila mushroom body: the roles of eyeless and dachshund, Development, 127, 3475, 10.1242/dev.127.16.3475

Osumi, 1997, Pax-6 is involved in the specification of hindbrain motor neuron subtype, Development, 124, 2961, 10.1242/dev.124.15.2961

Patel, 1989, Expression of engrailed proteins in arthropods, annelids, and chordates, Cell, 58, 955, 10.1016/0092-8674(89)90947-1

Quiring, 1994, Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans, Science, 265, 785, 10.1126/science.7914031

Rothberg, 1988, slit: an EGF-homologous of D. melanogaster involved in the development of the embryonic central nervous system, Cell, 55, 1047, 10.1016/0092-8674(88)90249-8

Stoykova, 1996, Forebrain patterning defects in Small eye mutant mice, Development, 122, 3453, 10.1242/dev.122.11.3453

Stoykova, 1997, Pax6-dependent regulation of adhesive patterning, R-cadherin expression and boundary formation in developing forebrain, Development, 124, 3765, 10.1242/dev.124.19.3765

Tautz, 1989, A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback, Chromosoma, 98, 81, 10.1007/BF00291041

Therianos, 1995, Embryonic development of the Drosophila brain: formation of commissural and descending pathways, Development, 121, 3849, 10.1242/dev.121.11.3849

Ton, 1991, Positional cloning and characterization of a paired box- and homeobox-containing gene from the aniridia region, Cell, 67, 1059, 10.1016/0092-8674(91)90284-6

van Vactor, 1993, Genes that control neuromuscular specificity in Drosophila, Cell, 73, 1137, 10.1016/0092-8674(93)90643-5

Walldorf, 1992, Empty spiracles, a gap gene containing a homeobox involved in Drosophila head development, EMBO J., 11, 2247, 10.1002/j.1460-2075.1992.tb05284.x

Walther, 1991, Pax-6, a murine paired box gene, is expressed in the developing CNS, Development, 113, 1435, 10.1242/dev.113.4.1435

Warren, 1997, Roles of Pax-6 in murine diencephalic development, Development, 124, 1573, 10.1242/dev.124.8.1573

Wieschaus, 1992, orthodenticle activity is required for the development of medial structures in the larval and adult epidermis of Drosophila, Development, 115, 801, 10.1242/dev.115.3.801

Yang, 1995, Subdivision of the Drosophila mushroom bodies by enhancer-trap expression patterns, Neuron, 15, 45, 10.1016/0896-6273(95)90063-2