Different types, applications and limits of enabling excipients of pharmaceutical dosage forms
Tài liệu tham khảo
Lipinksi, 2002, Poor aqueous solubility — an industry wide problem in drug discovery, Am Pharm Rev, 5, 82
Amidon, 1995, A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability, Pharm Res, 12, 413, 10.1023/A:1016212804288
Li, 2012, Enhanced bioavailability of a poorly water-soluble weakly basic compound using a combination approach of solubilization agents and precipitation inhibitors: a case study, Mol Pharm, 9, 1100, 10.1021/mp200352q
Holm, 2006, Optimization of self-microemulsifying drug delivery systems (SMEDDS) using a D-optimal design and the desirability function, Drug Dev Ind Pharm, 23, 1025, 10.1080/03639040600559024
Gursoy, 2004, Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs, Biomed Pharmacother, 58, 173, 10.1016/j.biopha.2004.02.001
Tønsberg, 2010, Effects of polysorbate 80 on the in-vitro precipitation and oral bioavailability of halofantrine from polyethylene glycol 400 formulations in rats, J Pharm Pharmacol, 62, 63, 10.1211/jpp.62.01.0006
Serajuddin, 2007, Salt formation to improve drug solubility, Adv Drug Deliv Rev, 59
Sarmah, 2017, First-line antituberculosis drug, pyrazinamide, its pharmaceutically relevant cocrystals and a salt, Acta Cryst, B73, 1007
Reddy, 2009, Cocrystals and salts of gabapentin: pH dependent cocrystal stability and solubility, Cryst Growth Des, 9, 378, 10.1021/cg800587y
Thorat, 2015, Drug-drug molecular salt hydrate of an anticancer drug gefitinib and a loop diuretic drug furosemide: an alternative for multidrug treatment, J Pharm Sci, 104, 4207, 10.1002/jps.24651
Viscomi, 2008, Crystal forms of rifaximin and their effect on pharmaceutical properties, Cryst Eng Comm, 10, 1074, 10.1039/b717887e
Williams, 2013, Strategies to address low drug solubility in discovery and development, Pharmacol Rev, 65, 315, 10.1124/pr.112.005660
Stephenson, 2011, Physical stability of salts of weak bases in the solid‐state, J Pharm Sci, 100, 1607, 10.1002/jps.22405
Miller, 2012, The solubility-permeability interplay when using cosolvents for solubilization: revising the way we use solubility-enabling formulations, Mol Pharm, 9, 581, 10.1021/mp200460u
Miyako, 2010, Solubility enhancement of hydrophobic compounds by cosolvents: role of solute hydrophobicity on the solubilization effect, Int J Pharm, 393, 48, 10.1016/j.ijpharm.2010.03.059
Booth, 2012, Mechanism of hydrophobic drug solubilization by small molecule hydrotropes, J Phys Chem B, 116, 14915, 10.1021/jp309819r
Vuković, 2013, Solubilization of therapeutic agents in micellar nanomedicines, Langmuir, 29, 15747, 10.1021/la403264w
Mennini, 2014, Development of a chitosan-derivative micellar formulation to improve celecoxib solubility and bioavailability, Drug Dev Ind Pharm, 40, 1494, 10.3109/03639045.2013.831440
Kadam, 2009, Solubilization of poorly water-soluble drug carbamezapine in pluronic micelles: effect of molecular characteristics, tem- perature and added salt on the solubilizing capacity, Colloids Surf B Biointerfaces, 72, 141, 10.1016/j.colsurfb.2009.03.027
di Cagno, 2014, β-Cyclodextrin-dextran polymers for the solubilization of poorly soluble drugs, Int J Pharm, 468, 258, 10.1016/j.ijpharm.2014.04.029
Muankaew, 2014, Effect of γ-cyclodextrin on solubilization and complexation of irbesartan: influence of pH and excipients, Int J Pharm, 474, 80, 10.1016/j.ijpharm.2014.08.013
Suzuki, 2017, New nano-matrix oral formulation of nanoprecipitated cyclosporine A prepared with multi-inlet vortex mixer, Int J Pharm, 516, 116, 10.1016/j.ijpharm.2016.11.031
Sun, 2012, Effect of particle size on solubility, dissolution rate, and oral bioavailability: evaluation using coenzyme Q10 as naked nanocrystals, Int J Nanomed, 7, 5733
Junghanns, 2008, Nanocrystal technology, drug delivery and clinical applications, Int J Nanomed, 3, 295
Tanaka, 2017, In vivo analysis of supersaturation/precipitation/absorption behavior after oral administration of pioglitazone hydrochloride salt; determinant site of oral absorption, Eur J Pharm Sci, 106, 431, 10.1016/j.ejps.2017.06.011
Tsume, 2017, The impact of supersaturation level for oral absorption of BCS class IIb drugs, dipyridamole and ketoconazole, using in vivo predictive dissolution system: Gastrointestinal Simulator (GIS), Eur J Pharm Sci, 102, 126, 10.1016/j.ejps.2017.02.042
Bevernage, 2012, Drug precipitation-permeation interplay: supersaturation in an absorptive environment, Eur J Pharm Biopharm, 82, 424, 10.1016/j.ejpb.2012.07.009
Ali, 2009, Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors, Int J Pharm, 375, 107, 10.1016/j.ijpharm.2009.03.029
Liu, 2015, Effect of drug physico-chemical properties on the efficiency of top-down process and characterization of nanosuspension, Expert Opin Drug Deliv, 12, 1741, 10.1517/17425247.2015.1057566
Chan, 2011, Production methods for nanodrug particles using the bottom-up approach, Adv Drug Deliv Rev, 63, 406, 10.1016/j.addr.2011.03.011
Liversidge GG, Cundy KC, Bishop JF, Czekai DA. Surface modified drug nanoparticles. US 5145684. 1992.
Deng, 2010, Understanding the structure and stability of paclitaxel nanocrystals, Int J Pharm, 390, 242, 10.1016/j.ijpharm.2010.02.013
Chiou, 1969, Preparation and dissolution characteristics of several fast-release solid dispersions of griseofulvin, J Pharm Sci, 58, 1505, 10.1002/jps.2600581218
Tian, 2014, Using Flory–Huggins phase diagrams as a pre-formulation tool for the production of amorphous solid dispersions: a comparison between hot-melt extrusion and spray drying, J Pharm Pharmacol, 66, 256, 10.1111/jphp.12141
Tabbakhian, 2014, Dissolution enhancement of glibenclamide by solid dispersion: solvent evaporation versus a supercritical fluid-based solvent–antisolvent technique, Res Pharm Sci, 9, 337
Milne, 2015, The stabilization of amorphous zopiclone in an amorphous solid dispersion, AAPS PharmSciTech, 16, 1190, 10.1208/s12249-015-0302-4
Bouchal, 2015, Fast dissolving cyclodextrin complex of piroxicam in solid dispersion part I: influence of β-CD and HPβ-CD on the dissolution rate of piroxicam, Int J Pharm, 478, 625, 10.1016/j.ijpharm.2014.12.019
Pouton, 2000, Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and ‘self-microemulsifying’ drug delivery systems, Eur J Pharm Sci, 11, S93, 10.1016/S0928-0987(00)00167-6
Čerpnjak, 2015, Development of a solid self-microemulsifying drug delivery system (SMEDDS) for solubility enhancement of naproxen, Drug Dev Ind Pharm, 41, 1548, 10.3109/03639045.2014.971031
Agrawal, 2015, Formulation of solid self-nanoemulsifying drug delivery systems using N-methyl pyrrolidone as cosolvent, Drug Dev Ind Pharm, 41, 594, 10.3109/03639045.2014.886695
Patel, 2015, Development and optimization of solid self nanoemulsifying drug delivery (S-SNEDDS) using D-optimal design for improvement of oral bioavailability of amiodarone hydrochloride, Curr Drug Deliv, 12, 745, 10.2174/1567201812666150302122501
Rubino, 2002, Cosolvents and cosolvency
Kipp, 2007, Solubilizing systems for parenteral formulation development — small molecules, 7, 309
Akers, 2002, Excipient-drug interactions in parenteral formulations, J Pharm Sci, 91, 2283, 10.1002/jps.10154
Strickley, 2004, Solubilizing excipients in oral and injectable formulations, Pharm Res, 21, 201, 10.1023/B:PHAM.0000016235.32639.23
Tønsberg, 2011, Effect of bile on the oral absorption of halofantrine in polyethylene glycol 400 and polysorbate 80 formulations dosed to bile duct cannulated rats, J Pharm Pharmacol Rev, 63, 817, 10.1111/j.2042-7158.2011.01286.x
Jouyban, 2014, Solubility of fluphenazine decanoate in aqueous mixtures of polyethylene glycols 400 and 600 at various temperatures, Fluid Phase Equilib, 368, 58, 10.1016/j.fluid.2014.01.044
Damian, 2000, Physicochemical characterisation of solid dispersions of the antiviral agent UC-781 with polyethylene glycol 6000 and Gelucire 44/14, Eur J Pharm Sci, 10, 311, 10.1016/S0928-0987(00)00084-1
Ogawa, 2018, Improvement in the water solubility of drugs with a solid dispersion system by spray drying and hot-melt extrusion with using the amphiphilic polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer and d-mannitol, Eur J Pharm Sci, 111, 205, 10.1016/j.ejps.2017.09.014
Ha, 2017, Solubility of cilostazol in the presence of polyethylene glycol 4000, polyethylene glycol 6000, polyvinylpyrrolidone K30, and poly(1-vinylpyrrolidone-co-vinyl acetate) at different temperatures, J Chem Thermodyn, 113, 6, 10.1016/j.jct.2017.05.040
Tang, 2013, Key structure of Brij for overcoming multidrug resistance in cancer, Biomacromolecules, 14, 424, 10.1021/bm301661w
Tomsic, 2006, Ternary systems of nonionic surfactant Brij 35, water and various simple alcohols: structural investigations by small-angle X-ray scattering and dynamic light scattering, J Colloid Interface Sci, 294
Valizadeh, 2004, Physicochemical characterization of solid dispersions of indomethacin with PEG 6000, Myrj 52, lactose, sorbitol, dextrin, and Eudragit E100, Drug Dev Ind Pharm, 30, 303, 10.1081/DDC-120030426
Rajebahadur, 2006, Mechanistic study of solubility enhancement of nifedipine using vitamin E TPGS or solutol HS-15, Drug Deliv, 13, 201, 10.1080/10717540500316094
Kaur, 2017, Developments of polysorbate (tween) based microemulsions: preclinical drug delivery, toxicity and antimicrobial applications, Int J Pharm, 29, 134, 10.1016/j.ijpharm.2017.06.059
Milovic, 2012, Characterization and evaluation of solid self-microemulsifying drug deliverysystems with porous carriers as systems for improved carbamazepine release, Int J Pharm, 436
Joshi, 2004, Bioavailability enhancement of a poorly water-soluble drug by solid dispersion in polyethylene glycol-polysorbate 80 mixture, Int J Pharm, 269, 251, 10.1016/j.ijpharm.2003.09.002
Nekkanti, 2010, Solid self-microemulsifying formulation for candesartan cilexetil, AAPS Pharm Sci Tech, 11, 9, 10.1208/s12249-009-9347-6
Göke, 2018, Novel strategies for the formulation and processing of poorly water-soluble drugs, Eur J Pharm Biopharm, 126, 40, 10.1016/j.ejpb.2017.05.008
Gibson, 2007, Lipid-based excipients for oral drug delivery, 33
Cao, 2004, Predictive relationships for the effects of triglyceride ester concentration and water uptake on solubility and partitioning of small molecules into lipid vehicles, J Pharm Sci, 93, 2768, 10.1002/jps.20126
Li, 2017, Effect of ionization of drug on drug solubilization in SMEDDS prepared using Capmul MCM and caprylic acid, Asian J Pharm, 12, 73
Tomsic, 2006, Water-Tween 40/Imwitor 308-isopropyl myristate microemulsions as delivery systems for ketoprofen: small-angle X-ray scattering study, Int J Pharm, 327, 170, 10.1016/j.ijpharm.2006.07.035
Bu, 2017, Assessment of cell viability and permeation enhancement in presence of lipid-based self-emulsifying drug delivery systems using Caco-2 cell model: polysorbate 80 as the surfactant, Eur J Pharm Sci, 99, 350, 10.1016/j.ejps.2016.12.018
Vrignaud, 2012, Design, optimization and in vitro evaluation of reverse micelle-loaded lipid nanocarriers containing erlotinib hydrochloride, Int J Pharm, 436, 194, 10.1016/j.ijpharm.2012.06.026
Harisa, 2015, Simvastatin nanolipid carriers decreased hypercholesterolemia induced cholesterol inclusion and phosphatidylserine exposure on human erythrocytes, J Mol Liq, 208, 202, 10.1016/j.molliq.2015.04.005
Park, 2017, Comparison of a revaprazan-loaded solid dispersion, solid SNEDDS and inclusion compound: physicochemical characterisation and pharmacokinetics, Colloids Surf B Biointerfaces, 162, 420, 10.1016/j.colsurfb.2017.12.017
Elsheikh, 2012, Nanoemulsion liquid preconcentrates for raloxifene hydrochloride: optimization and in vivo appraisal, Int J Nanomed, 7, 3787
Zhao, 2016, Preparation and evaluation of valsartan by a novel semi-solid self-microemulsifying delivery system using Gelucire 44/14, Drug Dev Ind Pharm, 42, 1545, 10.3109/03639045.2016.1151034
Devalapally, 2013, Evaluation of a nanoemulsion formulation strategy for oral bioavailability enhancement of danazol in rats and dogs, J Pharm Sci, 102, 3808, 10.1002/jps.23667
Hussein, 2012, Enhancement of the in-vitro dissolution and in-vivo oral bioavailability of silymarin from liquid-filled hard gelatin capsules of semisolid dispersion using Gelucire 44/14 as a carrier, Pharmazie, 67, 209
Huo, 2017, Preparation and comparison of tacrolimus-loaded solid dispersion and self-microemulsifying drug delivery system by in vitro/in vivo evaluation, Eur J Pharm Sci, 114, 74, 10.1016/j.ejps.2017.12.002
Matsaridou, 2012, The influence of surfactant HLB and oil/surfactant ratio on the formation and properties of self-emulsifying pellets and microemulsion reconstitution, AAPS PharmSciTech, 13, 1319, 10.1208/s12249-012-9855-7
Shakeel, 2013, Impact of various nonionic surfactants on self-nanoemulsification efficiency of two grades of Capryol (Capryol-90 and Capryol-PGMC), J Mol Liq, 182, 57, 10.1016/j.molliq.2013.03.011
Shakeel, 2014, Self-nanoemulsifying performance of two grades of Lauroglycol (Lauroglycol-90 and Lauroglycol-FCC) in the presence of mixed nonionic surfactants, Pharm Dev Technol, 19, 799, 10.3109/10837450.2013.829099
Marsh, 2013
Pichot, 2013, Phospholipids at the interface: current trends and challenges, Int J Mol Sci, 14, 11767, 10.3390/ijms140611767
Tran, 2016, Formulation and characterization of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine, Int J Pharm, 502, 151, 10.1016/j.ijpharm.2016.02.026
Yu, 2010, Enhancement of oral bioavailability of the poorly water-soluble drug silybin by sodium cholate/phospholipid-mixed micelles, Acta Pharmacol Sin, 31, 759, 10.1038/aps.2010.55
Prabhu, 2001, Enhancement of dissolution of ethopropazine using solid dispersions prepared with phospholipid and/or polyethylene glycol, Drug Dev Ind Pharm, 27, 413, 10.1081/DDC-100104316
Uhl, 2016, A liposomal formulation for the oral application of the investigational hepatitis B drug Myrcludex B, Eur J Pharm Biopharm, 103, 159, 10.1016/j.ejpb.2016.03.031
Small, 1971, The physical chemistry of cholanic acids, 249
Kratohvil, 1986, How large are the micelles of di-a-hydroxy bile salts at the critical micellization concentrations in aqueous electrolyte solutions? Results for sodium taurodeoxycholate and sodium deoxycholate, Langmuir, 2, 256, 10.1021/la00068a026
Stojančević, 2013, Application of bile acids in drug formulation and delivery, Front Life Sci, 7, 112, 10.1080/21553769.2013.879925
Song, 2014, Superhydrogels of nanotubes capable of capturing heavy-metal ions, Chem Asian J, 9, 245, 10.1002/asia.201300892
Margulis-Goshen, 2013, Drug-loaded nanoparticles and supramolecular nanotubes formed from a volatile microemulsion with bile salt derivatives, Phys Chem Chem Phys, 15, 6016, 10.1039/c3cp50258a
Fanun, 2008, Surfactant chain length effect on the structural parameters of nonionic microemulsions, J Dispers Sci Technol, 29, 289, 10.1080/01932690701707704
Fanun, 2009, Oil type effect on diclofenac solubilization in mixed nonionic surfactants microemulsions, Colloids Surf A, 343, 75, 10.1016/j.colsurfa.2009.01.032
Piao, 2008, A novel solid-in-oil nanosus- pension for transdermal delivery of diclofenac sodium, Pharm Res, 25, 896, 10.1007/s11095-007-9445-7
Klang, 2011, Development of sucrose stearate-based nanoemulsions and optimisation through gamma-cyclodextrin, Eur J Pharm Biopharm, 79, 58, 10.1016/j.ejpb.2011.01.010
Marton, 2005, Increased solubility applying solid-in-solid solutions, Eur J Pharm Sci, 25S1, S155
Szűts, 2008, Study of the effects of drugs on the structures of sucrose esters and the effects of solid-state interactions on drug release, J Pharm Biomed Anal, 48, 1136, 10.1016/j.jpba.2008.08.028
Granero, 2008, Synthesis, characterization and in vitro release studies of a new acetazolamide-HP-CD-TEA inclusion complex, Eur J Med Chem, 43, 464, 10.1016/j.ejmech.2007.03.037
Loftsson, 2012, Cyclodextrins as functional excipients: methods to enhance complexation efficiency, J Pharm Sci, 101, 3019, 10.1002/jps.23077
Jung, 2016, Improved oral absorption of tacrolimus by a solid dispersion with hypromellose and sodium lauryl sulfate, Int J Biol Macromol, 83, 282, 10.1016/j.ijbiomac.2015.11.063
Jermain, 2018, Amorphous solid dispersions and nanocrystal technologies for poorly water-soluble drug delivery – an update, Int J Pharm, 535, 379, 10.1016/j.ijpharm.2017.10.051
Ghebremeskel, 2007, Use of surfactants as plasticizers in preparing solid dispersions of poorly soluble API: Selection of polymer–surfactant combinations using solubility parameters and testing the processability, Int J Pharm, 328, 119, 10.1016/j.ijpharm.2006.08.010
Shakeel, 2017, Solubility and thermodynamic function of apremilast in different (Transcutol+water) cosolvent mixtures: measurement, correlation and molecular interactions, J Ind Eng Chem, 56, 99, 10.1016/j.jiec.2017.07.002
Abdelbary, 2013, Self nano-emulsifying simvastatin based tablets: design and in vitro/in vivo evaluation, Pharm Dev Technol, 18, 1294, 10.3109/10837450.2012.672989
Priotti, 2017, Application of fluorescence emission for characterization of albendazole and ricobendazole micellar systems: elucidation of the molecular mechanism of drug solubilization process, AAPS PharmSciTech, 1
Perissutti, 2002, Preparation of extruded carbamazepine and PEG 4000 as a potential rapid release dosage form, Eur J Pharm Biopharm, 53, 125, 10.1016/S0939-6411(01)00209-0
Beig, 2016, Hydrotropic solubilization of lipophilic drugs for oral delivery: the effects of urea and nicotinamide on carbamazepine solubility–permeability interplay, Front Pharmacol, 7, 379, 10.3389/fphar.2016.00379
Nguyen-Kim, 2016, Solubilization of active ingredients of different polarity in Pluronic® micellar solutions — correlations between solubilizate polarity and solubilization site, J Colloid Interface Sci, 477, 94, 10.1016/j.jcis.2016.05.017
Yuvaraja, 2014, Enhancement of carvedilol solubility by solid dispersion technique using cyclodextrins, water soluble polymers and hydroxyl acid, J Pharm Biomed Anal, 96, 10, 10.1016/j.jpba.2014.03.019
Rawat, 2004, Solubility enhancement of celecoxib using beta-cyclodextrin inclusion complexes, Eur J Pharm Biopharm, 57, 263, 10.1016/j.ejpb.2003.10.020
Gupta, 2004, Stability and solubility of celecoxib-PVP amorphous dispersions: a molecular perspective, Pharm Res, 21, 1762, 10.1023/B:PHAM.0000045226.42859.b8
Kaukonen, 2004, Drug solubilization behavior during in vitro digestion of simple triglyceride lipid solution formulations, Pharm Res, 21, 245, 10.1023/B:PHAM.0000016282.77887.1f
Chiu, 2003, Human jejunal permeability of cyclosporin A: influence of surfactants on P-glycoprotein efflux in Caco-2 cells, Pharm Res, 20, 749, 10.1023/A:1023481418576
Inugala, 2015, Solid self-nanoemulsifying drug delivery system (S-SNEDDS) of darunavir for improved dissolution and oral bioavailability: in vitro and in vivo evaluation, Eur J Pharm Sci, 74, 1, 10.1016/j.ejps.2015.03.024
El-Houssieny, 2014, Enhancement of solubility of dexibuprofen applying mixed hydrotropic solubilization technique, Drug Discov Ther, 8, 178, 10.5582/ddt.2014.01019
Rashid, 2015, Effect of hydroxypropylcellulose and Tween 80 on physicochemical properties and bioavailability of ezetimibe-loaded solid dispersion, Carbohydr Polym, 130, 26, 10.1016/j.carbpol.2015.04.071
Azad, 2018, Stable and fast-dissolving amorphous drug composites preparation via impregnation of Neusilin® UFL2, J Pharm Sci, 107, 170, 10.1016/j.xphs.2017.10.007
Alexander, 2012, Effect of temperature, cosolvent, and added drug on Pluronic-flurbiprofen micellization, J Phys Chem B, 116, 11545, 10.1021/jp303185m
Aly, 2003, Enhancement of the dissolution rate and bioavailability of glipizide through cyclodextrin inclusion complex, Pharm Technol, 27, 54
Agrawal, 2015, Self emulsifying drug delivery system for enhanced solubility and dissolution of glipizide, Colloids Surf B Biointerfaces, 126, 553, 10.1016/j.colsurfb.2014.11.022
Ribeiro, 2012, Solubilisation capacity of Brij surfactants, Int J Pharm, 436, 631, 10.1016/j.ijpharm.2012.07.032
Oliveira, 2011, The effect of polymeric additives on the solubilisation of a poorly-soluble drug in micellar solutions of Pluronic F127, Int J Pharm, 409, 206, 10.1016/j.ijpharm.2011.02.025
Wong, 2006, Enhancement of the dissolution rate and oral absorption of a poorly water soluble drug by formation of surfactant-containing microparticles, Int J Pharm, 317, 61, 10.1016/j.ijpharm.2006.03.001
Holm, 2003, Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides, Eur J Pharm Sci, 20, 91, 10.1016/S0928-0987(03)00174-X
Abdul-Fattah, 2002, Preparation and in vitro evaluation of solid dispersions of halofantrine, Int J Pharm, 235, 17, 10.1016/S0378-5173(01)00941-3
Savjani, 2017, Design and optimization of itraconazole tablet employing solid dispersion, Asian J Pharm, 11
Miyake, 1999, Characterization of itraconazole/2-hydroxypropyl-beta-cyclodextrin inclusion complex in aqueous propylene glycol solution, Int J Pharm, 179, 237, 10.1016/S0378-5173(98)00393-7
Dahan, 2010, The solubility-permeability interplay in using cyclodextrins as pharmaceutical solubilizers: mechanistic modeling and application to progesterone, J Pharm Sci, 99, 2739, 10.1002/jps.22033
Sinha, 2010, Solid dispersion as an approach for bioavailability enhancement of poorly water-soluble drug ritonavir, AAPS PharmSciTech, 11, 518, 10.1208/s12249-010-9404-1
Seo, 2015, Solid self-nanoemulsifying drug delivery system (SNEDDS) for enhanced oral bioavailability of poorly water-soluble tacrolimus: physicochemical characterisation and pharmacokinetics, J Microencapsul, 32, 503, 10.3109/02652048.2015.1057252
Modi, 2007, A comparative solubility enhancement profile of valdecoxib with different solubilization approaches, Indian J Pharm Sci, 69, 274, 10.4103/0250-474X.33156
Barakat, 2010, Enhanced oral bioavailability of etodolac by self-emulsifying systems: in-vitro and in-vivo evaluation, J Pharm Pharmacol, 62, 173, 10.1211/jpp.62.02.0004
Singh, 2013, Optimized nanoemulsifying systems with enhanced bioavailability of carvedilol, Colloids Surf B Biointerfaces, 101, 465, 10.1016/j.colsurfb.2012.07.017
Brouwers, 2009, Supersaturating drug delivery systems: the answer to solubility-limited oral bioavailability?, J Pharm Sci, 98, 2549, 10.1002/jps.21650
Ruble, 2006, The effect of commonly used vehicles on canine hematology and clinical chemistry values, J Am Assoc Lab Anim Sci, 45, 25
Tije, 2003, Pharmacological effects of formulation vehicles: implications for cancer chemotherapy, Clin Pharmacokinet, 42, 665, 10.2165/00003088-200342070-00005
Herbrink, 2018, Thermal stability study of crystalline and novel spray-dried amorphous nilotinib hydrochloride, J Pharm Biomed Anal, 148, 182, 10.1016/j.jpba.2017.10.001
Lehmkemper, 2018, Physical stability of API/polymer-blend amorphous solid dispersions, Eur J Pharm Biopharm, 124, 147, 10.1016/j.ejpb.2017.12.002
Lim, 2017, Re-evaluating the presumed superiority of amorphous nanoparticles over amorphous microscale solid dispersion in solubility enhancement of poorly soluble drugs, Eur J Pharm Sci, 109, 455, 10.1016/j.ejps.2017.09.010