Different prognosis of acute myeloid leukemia harboring monosomal karyotype with total or partial monosomies determined by FISH: Retrospective PALG study

Leukemia Research - Tập 37 - Trang 293-299 - 2013
Ewa Wawrzyniak1, Agnieszka Wierzbowska1, Aleksandra Kotkowska2, Monika Siemieniuk-Rys2, Tadeusz Robak1, Wanda Knopinska-Posluszny3, Agnieszka Klonowska4, Mariola Iliszko4, Renata Woroniecka5, Barbara Pienkowska-Grela5, Anna Ejduk6, Malgorzata Wach7, Ewa Duszenko8, Anna Jaskowiec8, Malgorzata Jakobczyk9, Barbara Mucha10, Joanna Kosny1, Agnieszka Pluta1, Sebastian Grosicki11, Jerzy Holowiecki12
1Department of Hematology, Medical University, Lodz, Poland
2Department of Hematology, Copernicus Memorial Hospital, Lodz, Poland
3Department of Hematology and Transplantology, Medical University, Gdansk, Poland
4Department of Biology and Genetics, Medical University, Gdansk, Poland
5Cytogenetic Laboratory, M. Sklodowska-Curie Memorial Cancer Center and Institute, Warsaw, Poland
6Department of Hematology, Institute of Hematology and Blood Transfusion, Warsaw, Poland
7Department of Hematooncology and Bone Marrow Transplantation, Medical University, Lublin, Poland
8Department of Hematology, Medical University, Wroclaw, Poland
9Department of Hematology, Collegium Medicum of Jagiellonian University, Cracow, Poland
10Department of Clinical Genetics, Collegium Medicum of Nicolaus Copernicus University, Bydgoszcz, Poland
11Department of Hematology, City Hospital, Chorzow, Poland
12Department of Bone Marrow Transplantation, Comprehensive Cancer Center, M. Sklodowska-Curie Memorial Institute, Gliwice, Poland

Tài liệu tham khảo

Breems, 2008, Monosomal karyotype in acute myeloid leukemia: a better indicator of poor prognosis than a complex karyotype, J Clin Oncol, 26, 4791, 10.1200/JCO.2008.16.0259 Breems, 2011, Acute myeloid leukemia with monosomal karyotype at the far end of the unfavorable prognostic spectrum, Haematologica, 96, 491, 10.3324/haematol.2011.043208 Grimwade, 2010, Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials, Blood, 116, 354, 10.1182/blood-2009-11-254441 Medeiros, 2010, Prognostic impact of monosomal karyotype in young adult and elderly acute myeloid leukemia: the Southwest Oncology Group (SWOG) experience, Blood, 116, 2224, 10.1182/blood-2010-02-270330 Perrot, 2011, Dismal prognostic value of monosomal karyotype in elderly patients with acute myeloid leukemia: a GOELAMS study of 186 patients with unfavorable cytogenetic abnormalities, Blood, 118, 679, 10.1182/blood-2010-09-307264 Oran, 2011, Monosomal karyotype provides better prognostic prediction after allogeneic stem cell transplantation in patients with acute myelogenous leukemia, Biol Blood Marrow Transplant, 17, 356, 10.1016/j.bbmt.2010.05.012 Göhring, 2010, Complex karyotype newly defined: the strongest prognostic factor in advanced childhood myelodysplastic syndrome, Blood, 116, 3766, 10.1182/blood-2010-04-280313 Patnaik, 2011, Monosomal karyotype in myelodysplastic syndromes, with or without monosomy 7 or 5, is prognostically worse than an otherwise complex karyotype, Leukemia, 25, 266, 10.1038/leu.2010.258 Vaidya, 2011, Monosomal karyotype in primary myelofibrosis is detrimental to both overall and leukemia-free survival, Blood, 117, 5612, 10.1182/blood-2010-11-320002 Mrózek, 2008, Cytogenetic, molecular genetic, and clinical characteristics of acute myeloid leukemia with a complex karyotype, Semin Oncol, 35, 365, 10.1053/j.seminoncol.2008.04.007 Holowiecki, 2012, Cladribine, but not fludarabine, added to daunorubicin and cytarabine during induction prolongs survival of patients with acute myeloid leukemia: multicenter, randomized phase III study, J Clin Oncol, 10, 2441, 10.1200/JCO.2011.37.1286 Shaffer, 2009 Mrózek, 2002, Spectral karyotyping in patients with acute myeloid leukemia and complex karyotype shows hidden aberrations, including recurrent overrepresentation of 21q, 11q, and 22q, Genes Chromosomes Cancer, 34, 137, 10.1002/gcc.10027 Schoch, 2002, Loss of genetic material is more common than gain in acute myeloid leukemia with complex aberrant karyotype: a detailed analysis of 125 cases using conventional chromosome analysis and fluorescence in situ hybridization including 24-color FISH, Genes Chromosomes Cancer, 35, 20, 10.1002/gcc.10088 Rücker, 2012, TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome, Blood, 119, 2114, 10.1182/blood-2011-08-375758 Haferlach, 2012, Prognostic value of “monosomal karyotype” in comparison to “complex aberrant karyotype” in acute myeloid leukemia: study on 824 cases with aberrant karyotype, Blood, 119, 2122, 10.1182/blood-2011-10-385781 Kayser, 2011, Monosomal karyotype in adult acute myeloid leukemia: prognostic impact and outcome after different treatment strategies, Blood, 119, 551, 10.1182/blood-2011-07-367508 Swerdlow, 2008 Galvan, 2010, Does monosomy 5 really exist in myelodysplastic syndromes and acute myeloid leukemia?, Leuk Res, 34, 1242, 10.1016/j.leukres.2010.03.022